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INSIDE BLOOD

Do V_L genes have prognostic relevance?

Alan Solomon

View Articletitled, Do VL genes have prognostic relevance?

Small steps to improve outcome in ALL

Seth J. Corey

View Articletitled, Small steps to improve outcome in ALL

Expanding use of rituximab in immunopathic disorders

Howard A. Liebman

View Articletitled, Expanding use of rituximab in immunopathic disorders

A kinder and gentler CHOP?

Howard Hochster

View Articletitled, A kinder and gentler CHOP?

Rituximab in the very young: benefits in AIHA, at what risk?

Dana C. Matthews

View Articletitled, Rituximab in the very young: benefits in AIHA, at what risk?

Sickle cell mouse models are hot!

Barry S. Coller

View Articletitled, Sickle cell mouse models are hot!

Location, location, location: targeting the endothelium

Samuel A. Santoro,Thomas P. Stricker

View Articletitled, Location, location, location: targeting the endothelium

Therapeutic remodeling of myeloma chromatin

P. Leif Bergsagel

View Articletitled, Therapeutic remodeling of myeloma chromatin

Xenogeneic studies of human stem cell plasticity

Diane S. Krause

View Articletitled, Xenogeneic studies of human stem cell plasticity

REVIEW ARTICLES

The role of the endothelium in severe sepsis and multiple organ dysfunction syndrome

William C. Aird

View Articletitled, The role of the endothelium in severe sepsis and multiple organ dysfunction syndrome

CHEMOKINES

AML-1A and AML-1B regulation of MIP-1α expression in multiple myeloma

Sun J. Choi,Tomoko Oba,Natalie S. Callander,Diane F. Jelinek,G. David Roodman

View Articletitled, AML-1A and AML-1B regulation of MIP-1α expression in multiple myeloma

Functional receptor for C3a anaphylatoxin is expressed by normal hematopoietic stem/progenitor cells, and C3a enhances their homing-related responses to SDF-1

Ryan Reca,Dimitrios Mastellos,Marcin Majka,Leah Marquez,Janina Ratajczak,Silvia Franchini,Aleksandra Glodek,Marek Honczarenko,Lynn A. Spruce,Anna Janowska-Wieczorek,John D. Lambris,Mariusz Z. Ratajczak

View Articletitled, Functional receptor for C3a anaphylatoxin is expressed by normal hematopoietic stem/progenitor cells, and C3a enhances their homing-related responses to SDF-1

CLINICAL OBSERVATIONS, INTERVENTIONS, AND THERAPEUTIC TRIALS

Prognostic significance of cytogenetic clonal evolution in patients with chronic myelogenous leukemia on imatinib mesylate therapy
Clinical Trials & Observations

Jorge E. Cortes,Moshe Talpaz,Francis Giles,Susan O'Brien,Mary Beth Rios,Jianqin Shan,Guillermo Garcia-Manero,Stefan Faderl,Deborah A. Thomas,William Wierda,Allessandra Ferrajoli,Sima Jeha,Hagop M. Kantarjian

View Articletitled, Prognostic significance of cytogenetic clonal evolution in patients with chronic myelogenous leukemia on imatinib mesylate therapy

Immunoglobulin light chain variable (V) region genes influence clinical presentation and outcome in light chain–associated amyloidosis (AL)
Clinical Trials & Observations

Roshini S. Abraham,Susan M. Geyer,Tammy L. Price-Troska,Cristine Allmer,Robert A. Kyle,Morie A. Gertz,Rafael Fonseca

View Articletitled, Immunoglobulin light chain variable (V) region genes influence clinical presentation and outcome in light chain–associated amyloidosis (AL)

Dexamethasone versus prednisone and daily oral versus weekly intravenous mercaptopurine for patients with standard-risk acute lymphoblastic leukemia: a report from the Children's Cancer Group
Clinical Trials & Observations

Bruce C. Bostrom,Martha R. Sensel,Harland N. Sather,Paul S. Gaynon,Mei K. La,Katherine Johnston,Gary R. Erdmann,Stuart Gold,Nyla A. Heerema,Raymond J. Hutchinson,Arthur J. Provisor,Michael E. Trigg

View Articletitled, Dexamethasone versus prednisone and daily oral versus weekly intravenous mercaptopurine for patients with standard-risk acute lymphoblastic leukemia: a report from the Children's Cancer Group

Monoclonal antibody treatment of mixed cryoglobulinemia resistant to interferon α with an anti-CD20
Clinical Trials & Observations

Domenico Sansonno,Valli De Re,Gianfranco Lauletta,Felicia Anna Tucci,Mauro Boiocchi,Franco Dammacco

View Articletitled, Monoclonal antibody treatment of mixed cryoglobulinemia resistant to interferon α with an anti-CD20

Efficacy and safety of rituximab in type II mixed cryoglobulinemia
Clinical Trials & Observations

Francesco Zaja,Salvatore De Vita,Cesare Mazzaro,Stefania Sacco,Daniela Damiani,Ginevra De Marchi,Angela Michelutti,Michele Baccarani,Renato Fanin,Gianfranco Ferraccioli

View Articletitled, Efficacy and safety of rituximab in type II mixed cryoglobulinemia

Unrelated donor stem cell transplantation compared with chemotherapy for children with acute lymphoblastic leukemia in a second remission: a matched-pair analysis
Clinical Trials & Observations

Anja Borgmann,Arend von Stackelberg,Reinhard Hartmann,Wolfram Ebell,Thomas Klingebiel,Christina Peters,Günter Henze,for the Berlin-Frankfurt-Münster Relapse Study Group

View Articletitled, Unrelated donor stem cell transplantation compared with chemotherapy for children with acute lymphoblastic leukemia in a second remission: a matched-pair analysis

CHOP is superior to CNOP in elderly patients with aggressive lymphoma while outcome is unaffected by filgrastim treatment: results of a Nordic Lymphoma Group randomized trial
Clinical Trials & Observations

Eva Ösby,Hans Hagberg,Stein Kvaløy,Lasse Teerenhovi,Harald Anderson,Eva Cavallin-Ståhl,Harald Holte,John Myhre,Hannu Pertovaara,Magnus Björkholm,for the Nordic Lymphoma Group (NLG)

View Articletitled, CHOP is superior to CNOP in elderly patients with aggressive lymphoma while outcome is unaffected by filgrastim treatment: results of a Nordic Lymphoma Group randomized trial

Continuous absence of metaphase-defined cytogenetic abnormalities, especially of chromosome 13 and hypodiploidy, ensures long-term survival in multiple myeloma treated with Total Therapy I: interpretation in the context of global gene expression
Clinical Trials & Observations

View Articletitled, Continuous absence of metaphase-defined cytogenetic abnormalities, especially of chromosome 13 and hypodiploidy, ensures long-term survival in multiple myeloma treated with Total Therapy I: interpretation in the context of global gene expression

Rituximab for the treatment of refractory autoimmune hemolytic anemia in children
Clinical Trials & Observations

Marco Zecca,Bruno Nobili,Ugo Ramenghi,Silverio Perrotta,Giovanni Amendola,Pasquale Rosito,Momcilo Jankovic,Paolo Pierani,Piero De Stefano,Mario Regazzi Bonora,Franco Locatelli

View Articletitled, Rituximab for the treatment of refractory autoimmune hemolytic anemia in children

Granulocyte colony-stimulating factor and the risk of secondary myeloid malignancy after etoposide treatment
Clinical Trials & Observations

Mary V. Relling,James M. Boyett,Javier G. Blanco,Susana Raimondi,Frederick G. Behm,John T. Sandlund,Gaston K. Rivera,Larry E. Kun,William E. Evans,Ching-Hon Pui

View Articletitled, Granulocyte colony-stimulating factor and the risk of secondary myeloid malignancy after etoposide treatment

Gemtuzumab ozogamicin: first clinical experiences in children with relapsed/refractory acute myeloid leukemia treated on compassionate-use basis
Clinical Trials & Observations

Christian M. Zwaan,Dirk Reinhardt,Selim Corbacioglu,Elisabeth R. van Wering,Jos P. M. Bökkerink,Wim J. E. Tissing,Ulf Samuelsson,Jay Feingold,Ursula Creutzig,Gertjan J. L. Kaspers

View Articletitled, Gemtuzumab ozogamicin: first clinical experiences in children with relapsed/refractory acute myeloid leukemia treated on compassionate-use basis

Clonal chromosomal aberrations in bone marrow cells of Fanconi anemia patients: gains of the chromosomal segment 3q26q29 as an adverse risk factor
Clinical Trials & Observations Brief Report

Holger Tönnies,Stefanie Huber,Jörn-Sven Kühl,Antje Gerlach,Wolfram Ebell,Heidemarie Neitzel

View Articletitled, Clonal chromosomal aberrations in bone marrow cells of Fanconi anemia patients: gains of the chromosomal segment 3q26q29 as an adverse risk factor

Utility of FDG-PET scanning in lymphoma by WHO classification
Clinical Trials & Observations Brief Report

Rebecca Elstrom,Liang Guan,Gary Baker,Khozaim Nakhoda,Jo-Anne Vergilio,Hongming Zhuang,Stephanie Pitsilos,Adam Bagg,Lisa Downs,Amit Mehrotra,Scott Kim,Abass Alavi,Stephen J. Schuster

View Articletitled, Utility of FDG-PET scanning in lymphoma by WHO classification

ERRATA

Erratum for vol. 100, p. 3155

View Articletitled, Erratum for vol. 100, p. 3155

HEMATOPOIESIS

Increased sensitivity of Fancc-deficient hematopoietic cells to nitric oxide and evidence that this species mediates growth inhibition by cytokines

Suzana Hadjur,Frank R. Jirik

View Articletitled, Increased sensitivity of Fancc-deficient hematopoietic cells to nitric oxide and evidence that this species mediates growth inhibition by cytokines

Reciprocal effects of C/EBPα and PKCδ on JunB expression and monocytic differentiation depend upon the C/EBPα basic region

Huaitian Liu,Jeffrey R. Keefer,Qian-fei Wang,Alan D. Friedman

View Articletitled, Reciprocal effects of C/EBPα and PKCδ on JunB expression and monocytic differentiation depend upon the C/EBPα basic region

HEMOSTASIS, THROMBOSIS, AND VASCULAR BIOLOGY

Induction of heme oxygenase-1 and stimulation of cGMP production by hemin in aortic tissues from hypertensive rats

Joseph Fomusi Ndisang,Lingyun Wu,Weimin Zhao,Rui Wang

View Articletitled, Induction of heme oxygenase-1 and stimulation of cGMP production by hemin in aortic tissues from hypertensive rats

Hyperhomocysteinemia accelerates atherosclerosis in cystathionine β-synthase and apolipoprotein E double knock-out mice with and without dietary perturbation

Hong Wang,XiaoHua Jiang,Fan Yang,John W. Gaubatz,Lang Ma,Mark J. Magera,XiaoFeng Yang,Peter B. Berger,William Durante,Henry J. Pownall,Andrew I. Schafer

View Articletitled, Hyperhomocysteinemia accelerates atherosclerosis in cystathionine β-synthase and apolipoprotein E double knock-out mice with and without dietary perturbation

Inactivation of the human P2Y₁₂ receptor by thiol reagents requires interaction with both extracellular cysteine residues, Cys17 and Cys270

Zhongren Ding,Soochong Kim,Robert T. Dorsam,Jianguo Jin,Satya P. Kunapuli

View Articletitled, Inactivation of the human P2Y12 receptor by thiol reagents requires interaction with both extracellular cysteine residues, Cys17 and Cys270

Megakaryocytes require thrombospondin-2 for normal platelet formation and function

Themis R. Kyriakides,Ponlapat Rojnuckarin,Michael A. Reidy,Kurt D. Hankenson,Thalia Papayannopoulou,Kenneth Kaushansky,Paul Bornstein

View Articletitled, Megakaryocytes require thrombospondin-2 for normal platelet formation and function

Neonatal or hepatocyte growth factor–potentiated adult gene therapy with a retroviral vector results in therapeutic levels of canine factor IX for hemophilia B

Lingfei Xu,Cuihua Gao,Mark S. Sands,Shi-Rong Cai,Timothy C. Nichols,Dwight A. Bellinger,Robin A. Raymer,Stephanie McCorquodale,Katherine Parker Ponder

View Articletitled, Neonatal or hepatocyte growth factor–potentiated adult gene therapy with a retroviral vector results in therapeutic levels of canine factor IX for hemophilia B

Elevated plasma factor VIII in a mouse model of low-density lipoprotein receptor–related protein deficiency

Niels Bovenschen,Joachim Herz,Jos M. Grimbergen,Peter J. Lenting,Louis M. Havekes,Koen Mertens,Bart J. M. van Vlijmen

View Articletitled, Elevated plasma factor VIII in a mouse model of low-density lipoprotein receptor–related protein deficiency

Regulation of tissue factor and inflammatory mediators by Egr-1 in a mouse endotoxemia model

Rafal Pawlinski,Brian Pedersen,Bettina Kehrle,William C. Aird,Rolf D. Frank,Mausumee Guha,Nigel Mackman

View Articletitled, Regulation of tissue factor and inflammatory mediators by Egr-1 in a mouse endotoxemia model

Targeting of the collagen-binding site on glycoprotein VI is not essential for in vivo depletion of the receptor

Valerie Schulte,Tamer Rabie,Miroslava Prostredna,Barsom Aktas,Sabine Grüner,Bernhard Nieswandt

View Articletitled, Targeting of the collagen-binding site on glycoprotein VI is not essential for in vivo depletion of the receptor

Transgenic sickle mice have vascular inflammation

John D. Belcher,Christopher J. Bryant,Julia Nguyen,Paul R. Bowlin,Miroslaw C. Kielbik,John C. Bischof,Robert P. Hebbel,Gregory M. Vercellotti

View Articletitled, Transgenic sickle mice have vascular inflammation

Src and phosphatidylinositol 3–kinase mediate soluble E-selectin–induced angiogenesis

Pawan Kumar,Mohammad A. Amin,Lisa A. Harlow,Peter J. Polverini,Alisa E. Koch

View Articletitled, Src and phosphatidylinositol 3–kinase mediate soluble E-selectin–induced angiogenesis

Overexpression of the platelet P2X₁ ion channel in transgenic mice generates a novel prothrombotic phenotype

Cécile Oury,Marijke J. E. Kuijpers,Emese Toth-Zsamboki,Arnaud Bonnefoy,Sophie Danloy,Ingrid Vreys,Marion A. H. Feijge,Rita De Vos,Jos Vermylen,Johan W. M. Heemskerk,Marc F. Hoylaerts

View Articletitled, Overexpression of the platelet P2X1 ion channel in transgenic mice generates a novel prothrombotic phenotype

ICAM-directed vascular immunotargeting of antithrombotic agents to the endothelial luminal surface: Presented in part as posters at the American Thoracic Society (ATS) Meeting, May 5-10, 2000, Toronto, ON, Canada.

Juan-Carlos Murciano,Silvia Muro,Lauren Koniaris,Melpo Christofidou-Solomidou,David W. Harshaw,Steven M. Albelda,D. Neil Granger,Douglas B. Cines,Vladimir R. Muzykantov

View Articletitled, ICAM-directed vascular immunotargeting of antithrombotic agents to the endothelial luminal surface: Presented in part as posters at the American Thoracic Society (ATS) Meeting, May 5-10, 2000, Toronto, ON, Canada.

IMMUNOBIOLOGY

Adenosine affects expression of membrane molecules, cytokine and chemokine release, and the T-cell stimulatory capacity of human dendritic cells

Elisabeth Panther,Silvia Corinti,Marco Idzko,Yared Herouy,Matthias Napp,Andrea la Sala,Giampiero Girolomoni,Johannes Norgauer

View Articletitled, Adenosine affects expression of membrane molecules, cytokine and chemokine release, and the T-cell stimulatory capacity of human dendritic cells

Antigen-primed CD8⁺ T cells can mediate resistance, preventing allogeneic marrow engraftment in the simultaneous absence of perforin-, CD95L-, TNFR1-, and TRAIL-dependent killing

Masanobu Komatsu,Michele Mammolenti,Monica Jones,Roland Jurecic,Thomas J. Sayers,Robert B. Levy

View Articletitled, Antigen-primed CD8+ T cells can mediate resistance, preventing allogeneic marrow engraftment in the simultaneous absence of perforin-, CD95L-, TNFR1-, and TRAIL-dependent killing

The heat-shock protein receptor CD91 is up-regulated in monocytes of HIV-1–infected “true” long-term nonprogressors

Justin Stebbing,Brian Gazzard,Louise Kim,Simon Portsmouth,Adrian Wildfire,Ian Teo,Mark Nelson,Mark Bower,Frances Gotch,Sunil Shaunak,Pramod Srivastava,Steve Patterson

View Articletitled, The heat-shock protein receptor CD91 is up-regulated in monocytes of HIV-1–infected “true” long-term nonprogressors

β₂-Microglobulin as a negative regulator of the immune system: high concentrations of the protein inhibit in vitro generation of functional dendritic cells

Jin Xie,Ying Wang,Muta E. Freeman, III,Bart Barlogie,Qing Yi

View Articletitled, β2-Microglobulin as a negative regulator of the immune system: high concentrations of the protein inhibit in vitro generation of functional dendritic cells

Gene expression profiling reveals a highly specialized genetic program of plasma cells

Gregory H. Underhill,David George,Eric G. Bremer,Geoffrey S. Kansas

View Articletitled, Gene expression profiling reveals a highly specialized genetic program of plasma cells

Supplemental data

Responding naive T cells differ in their sensitivity to Fas engagement: early death of many T cells is compensated by costimulation of surviving T cells

Mikael Maksimow,Minna Santanen,Sirpa Jalkanen,Arno Hänninen

View Articletitled, Responding naive T cells differ in their sensitivity to Fas engagement: early death of many T cells is compensated by costimulation of surviving T cells

Chronic lymphocytic leukemia B cells expressing AID display dissociation between class switch recombination and somatic hypermutation
Brief Report

Pablo Oppezzo,Françoise Vuillier,Yuri Vasconcelos,Gérard Dumas,Christian Magnac,Béatrice Payelle-Brogard,Otto Pritsch,Guillaume Dighiero

View Articletitled, Chronic lymphocytic leukemia B cells expressing AID display dissociation between class switch recombination and somatic hypermutation

NEOPLASIA

CD11c gene expression in hairy cell leukemia is dependent upon activation of the proto-oncogenes ras andjunD

Fotini Nicolaou,Jens M. Teodoridis,Heiyoung Park,Alexander Georgakis,Omid C. Farokhzad,Erwin P. Böttinger,Nicolas Da Silva,Philippe Rousselot,Christine Chomienne,Katalin Ferenczi,M. Amin Arnaout,C. Simon Shelley

View Articletitled, CD11c gene expression in hairy cell leukemia is dependent upon activation of the proto-oncogenes ras andjunD

Molecular heterogeneity in MCL defined by the use of specificV_H genes and the frequency of somatic mutations
Clinical Trials & Observations

Francisca I. Camacho,Patrocinio Algara,Antonia Rodrı́guez,Elena Ruı́z-Ballesteros,Manuela Mollejo,Nerea Martı́nez,José A. Martı́nez-Climent,Marcos González,Marisol Mateo,Alessia Caleo,Margarita Sánchez-Beato,J. Menárguez,Javier Garcı́a-Conde,Francesc Solé,Elı́as Campo,Miguel A. Piris

View Articletitled, Molecular heterogeneity in MCL defined by the use of specificVH genes and the frequency of somatic mutations

Mutated V_H genes and preferential V_H3-21 use define new subsets of mantle cell lymphoma
Clinical Trials & Observations

View Articletitled, Mutated VH genes and preferential VH3-21 use define new subsets of mantle cell lymphoma

Molecular sequelae of histone deacetylase inhibition in human malignant B cells

Nicholas Mitsiades,Constantine S. Mitsiades,Paul G. Richardson,Ciaran McMullan,Vassiliki Poulaki,Galinos Fanourakis,Robert Schlossman,Dharminder Chauhan,Nikhil C. Munshi,Teru Hideshima,Victoria M. Richon,Paul A. Marks,Kenneth C. Anderson

View Articletitled, Molecular sequelae of histone deacetylase inhibition in human malignant B cells

Nodular sclerosing Hodgkin disease: new grading predicts prognosis in intermediate and advanced stages
Clinical Trials & Observations

Sabine von Wasielewski,Jeremy Franklin,Robert Fischer,Klaus Hübner,Martin L. Hansmann,Volker Diehl,Axel Georgii,Reinhard von Wasielewski

View Articletitled, Nodular sclerosing Hodgkin disease: new grading predicts prognosis in intermediate and advanced stages

Kaposi sarcoma–associated viral cyclin K overrides cell growth inhibition mediated by oncostatin M through STAT3 inhibition

Amy Lundquist,Benjamin Barré,Frédéric Bienvenu,Jacques Hermann,Sylvie Avril,Olivier Coqueret

View Articletitled, Kaposi sarcoma–associated viral cyclin K overrides cell growth inhibition mediated by oncostatin M through STAT3 inhibition

Arsenic trioxide–induced apoptosis in myeloma cells: p53-dependent G₁ or G₂/M cell cycle arrest, activation of caspase-8 or caspase-9, and synergy with APO2/TRAIL: Presented in preliminary form at the 43rd annual meeting of the American Society of Hematology, Orlando, FL, December 8, 2001.⁴²

Qun Liu,Susan Hilsenbeck,Yair Gazitt

View Articletitled, Arsenic trioxide–induced apoptosis in myeloma cells: p53-dependent G1 or G2/M cell cycle arrest, activation of caspase-8 or caspase-9, and synergy with APO2/TRAIL: Presented in preliminary form at the 43rd annual meeting of the American Society of Hematology, Orlando, FL, December 8, 2001.42

Cell context–specific effects of the BCR-ABL oncogene monitored in hematopoietic progenitors

Stephane Wong,Jami McLaughlin,Donghui Cheng,Owen N. Witte

View Articletitled, Cell context–specific effects of the BCR-ABL oncogene monitored in hematopoietic progenitors

Free radical stress in chronic lymphocytic leukemia cells and its role in cellular sensitivity to ROS-generating anticancer agents

Yan Zhou,Elizabeth O. Hileman,William Plunkett,Michael J. Keating,Peng Huang

View Articletitled, Free radical stress in chronic lymphocytic leukemia cells and its role in cellular sensitivity to ROS-generating anticancer agents

Potentiation of dexamethasone-, paclitaxel-, and Ad-p53–induced apoptosis by Bcl-2 antisense oligodeoxynucleotides in drug-resistant multiple myeloma cells: Presented in abstract form at the 43rd annual meeting of the American Society of Hematology, Orlando, FL, December 10, 2001.³³

Qun Liu,Yair Gazitt

View Articletitled, Potentiation of dexamethasone-, paclitaxel-, and Ad-p53–induced apoptosis by Bcl-2 antisense oligodeoxynucleotides in drug-resistant multiple myeloma cells: Presented in abstract form at the 43rd annual meeting of the American Society of Hematology, Orlando, FL, December 10, 2001.33

Gene expression profile analysis of AIDS-related primary effusion lymphoma (PEL) suggests a plasmablastic derivation and identifies PEL-specific transcripts

Ulf Klein,Annunziata Gloghini,Gianluca Gaidano,Amy Chadburn,Ethel Cesarman,Riccardo Dalla-Favera,Antonino Carbone

View Articletitled, Gene expression profile analysis of AIDS-related primary effusion lymphoma (PEL) suggests a plasmablastic derivation and identifies PEL-specific transcripts

Supplemental data

PDE4 inhibitors activate a mitochondrial apoptotic pathway in chronic lymphocytic leukemia cells that is regulated by protein phosphatase 2A

Eun-Yi Moon,Adam Lerner

View Articletitled, PDE4 inhibitors activate a mitochondrial apoptotic pathway in chronic lymphocytic leukemia cells that is regulated by protein phosphatase 2A

Aberrant DNA methylation of p57KIP2 identifies a cell-cycle regulatory pathway with prognostic impact in adult acute lymphocytic leukemia

LanLan Shen,Minoru Toyota,Yutaka Kondo,Toshiro Obata,Sophia Daniel,Sherry Pierce,Kohzoh Imai,Hagop M. Kantarjian,Jean-Pierre J. Issa,Guillermo Garcia-Manero

View Articletitled, Aberrant DNA methylation of p57KIP2 identifies a cell-cycle regulatory pathway with prognostic impact in adult acute lymphocytic leukemia

Patterns of somatic mutations in V_H genes reveal pathways of clonal transformation from MGUS to multiple myeloma
Brief Report

Niklas Zojer,Heinz Ludwig,Michael Fiegl,Freda K. Stevenson,Surinder S. Sahota

View Articletitled, Patterns of somatic mutations in VH genes reveal pathways of clonal transformation from MGUS to multiple myeloma

PHAGOCYTES

Leukocyte antiadhesive actions of annexin 1: ALXR- and FPR-related anti-inflammatory mechanisms

Felicity N. E. Gavins,Simon Yona,Ahmad M. Kamal,Roderick J. Flower,Mauro Perretti

View Articletitled, Leukocyte antiadhesive actions of annexin 1: ALXR- and FPR-related anti-inflammatory mechanisms

Cytokine-mediated regulation of iron transport in human monocytic cells

Susanne Ludwiczek,Elmar Aigner,Igor Theurl,Günter Weiss

View Articletitled, Cytokine-mediated regulation of iron transport in human monocytic cells

G-protein–coupled receptor signaling in Syk-deficient neutrophils and mast cells

Attila Mócsai,Hong Zhang,Zoltán Jakus,Jiro Kitaura,Toshiaki Kawakami,Clifford A. Lowell

View Articletitled, G-protein–coupled receptor signaling in Syk-deficient neutrophils and mast cells

RED CELLS

Alternative 5′ exons and differential splicing regulate expression of protein 4.1R isoforms with distinct N-termini

Marilyn K. Parra,Sherry L. Gee,Mark J. Koury,Narla Mohandas,John G. Conboy

View Articletitled, Alternative 5′ exons and differential splicing regulate expression of protein 4.1R isoforms with distinct N-termini

Effects of combined chelation treatment with pyridoxal isonicotinoyl hydrazone analogs and deferoxamine in hypertransfused rats and in iron-loaded rat heart cells

Gabriela Link,Prem Ponka,Abraham M. Konijn,William Breuer,Z. Ioav Cabantchik,Chaim Hershko

View Articletitled, Effects of combined chelation treatment with pyridoxal isonicotinoyl hydrazone analogs and deferoxamine in hypertransfused rats and in iron-loaded rat heart cells

A band 3–based macrocomplex of integral and peripheral proteins in the RBC membrane

Lesley J. Bruce,Roland Beckmann,M. Leticia Ribeiro,Luanne L. Peters,Joel A. Chasis,Jean Delaunay,Narla Mohandas,David J. Anstee,Michael J.A. Tanner

View Articletitled, A band 3–based macrocomplex of integral and peripheral proteins in the RBC membrane

Excess hemoglobin digestion and the osmotic stability ofPlasmodium falciparum–infected red blood cells

Virgilio L. Lew,Teresa Tiffert,Hagai Ginsburg

View Articletitled, Excess hemoglobin digestion and the osmotic stability ofPlasmodium falciparum–infected red blood cells

TRANSFUSION MEDICINE

Transfusion-transmitted cytomegalovirus infection after receipt of leukoreduced blood products
Clinical Trials & Observations

W. Garrett Nichols,Thomas H. Price,Ted Gooley,Lawrence Corey,Michael Boeckh

View Articletitled, Transfusion-transmitted cytomegalovirus infection after receipt of leukoreduced blood products

TRANSPLANTATION

Albumin-expressing hepatocyte-like cells develop in the livers of immune-deficient mice that received transplants of highly purified human hematopoietic stem cells

Xiuli Wang,Shundi Ge,George McNamara,Qian-Lin Hao,Gay M. Crooks,Jan A. Nolta

View Articletitled, Albumin-expressing hepatocyte-like cells develop in the livers of immune-deficient mice that received transplants of highly purified human hematopoietic stem cells

Interleukin-7 improves CD4 T-cell reconstitution after autologous CD34 cell transplantation in monkeys

Jan Storek,Thurman Gillespy, III,Hailing Lu,Ansamma Joseph,Monja A. Dawson,Michael Gough,Julia Morris,Robert C. Hackman,Peter A. Horn,George E. Sale,Robert G. Andrews,David G. Maloney,Hans-Peter Kiem

View Articletitled, Interleukin-7 improves CD4 T-cell reconstitution after autologous CD34 cell transplantation in monkeys

Nephrotic syndrome with crescent formation and massive IgA deposition following allogeneic bone marrow transplantation for natural killer cell leukemia/lymphoma
Brief Report

Shinya Kimura,Akeyo Horie,Yoshiyuki Hiki,Chie Yamamoto,Satoru Suzuki,Junya Kuroda,Masayo Deguchi,Gen-ichi Kato,Takahiro Karasuno,Akira Hiraoka,Toshikazu Yoshikawa,Taira Maekawa

View Articletitled, Nephrotic syndrome with crescent formation and massive IgA deposition following allogeneic bone marrow transplantation for natural killer cell leukemia/lymphoma

CORRESPONDENCE

Reassessment of loss of heterozygosity within MLLin childhood acute lymphoblastic leukemia

Carina J. M. van Schooten,Lana M. Ellis,Ian M. Morison

View Articletitled, Reassessment of loss of heterozygosity within MLLin childhood acute lymphoblastic leukemia

The −1C>T mutation in the annexin A5gene does not affect plasma levels of annexin A5

Waander L. van Heerde,Heidi Kenis,Selene Schoormans,Paul Lap,Chris P. M. Reutelingsperger

View Articletitled, The −1C>T mutation in the annexin A5gene does not affect plasma levels of annexin A5

Agranulocytosis unresponsive to growth factors following rituximab in vivo purging

Andrea L. Rose,Alice M. Forsythe,David G. Maloney

View Articletitled, Agranulocytosis unresponsive to growth factors following rituximab in vivo purging

Issue Archive

Table of Contents

INSIDE BLOOD

REVIEW ARTICLES

CHEMOKINES

CLINICAL OBSERVATIONS, INTERVENTIONS, AND THERAPEUTIC TRIALS

Prognostic significance of cytogenetic clonal evolution in patients with chronic myelogenous leukemia on imatinib mesylate therapy Clinical Trials & Observations

Immunoglobulin light chain variable (V) region genes influence clinical presentation and outcome in light chain–associated amyloidosis (AL) Clinical Trials & Observations

Dexamethasone versus prednisone and daily oral versus weekly intravenous mercaptopurine for patients with standard-risk acute lymphoblastic leukemia: a report from the Children's Cancer Group Clinical Trials & Observations

Monoclonal antibody treatment of mixed cryoglobulinemia resistant to interferon α with an anti-CD20 Clinical Trials & Observations

Efficacy and safety of rituximab in type II mixed cryoglobulinemia Clinical Trials & Observations

Unrelated donor stem cell transplantation compared with chemotherapy for children with acute lymphoblastic leukemia in a second remission: a matched-pair analysis Clinical Trials & Observations

CHOP is superior to CNOP in elderly patients with aggressive lymphoma while outcome is unaffected by filgrastim treatment: results of a Nordic Lymphoma Group randomized trial Clinical Trials & Observations

Continuous absence of metaphase-defined cytogenetic abnormalities, especially of chromosome 13 and hypodiploidy, ensures long-term survival in multiple myeloma treated with Total Therapy I: interpretation in the context of global gene expression Clinical Trials & Observations

Rituximab for the treatment of refractory autoimmune hemolytic anemia in children Clinical Trials & Observations

Granulocyte colony-stimulating factor and the risk of secondary myeloid malignancy after etoposide treatment Clinical Trials & Observations

Gemtuzumab ozogamicin: first clinical experiences in children with relapsed/refractory acute myeloid leukemia treated on compassionate-use basis Clinical Trials & Observations

Clonal chromosomal aberrations in bone marrow cells of Fanconi anemia patients: gains of the chromosomal segment 3q26q29 as an adverse risk factor Clinical Trials & Observations Brief Report

Utility of FDG-PET scanning in lymphoma by WHO classification Clinical Trials & Observations Brief Report