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Volume 100, Issue 7

October 1 2002

In this Issue

INSIDE BLOOD
PLENARY PAPERS
ERRATA
REVIEW ARTICLES
CHEMOKINES
CLINICAL OBSERVATIONS, INTERVENTIONS, AND THERAPEUTIC TRIALS
GENE THERAPY
HEMATOPOIESIS
HEMOSTASIS, THROMBOSIS, AND VASCULAR BIOLOGY
IMMUNOBIOLOGY
NEOPLASIA
PHAGOCYTES
RED CELLS
TRANSFUSION MEDICINE
TRANSPLANTATION
BRIEF REPORTS
CORRESPONDENCE

INSIDE BLOOD

Epo-EpoR signaling not required for cardiovascular or neural development

Noëlle Paffett-Lugassy,Leonard I. Zon

View Articletitled, Epo-EpoR signaling not required for cardiovascular or neural development

Clonal lymphocytosis of uncertain significance (CLUS): what clues will CLUS yield?

John C. Byrd

View Articletitled, Clonal lymphocytosis of uncertain significance (CLUS): what clues will CLUS yield?

Murky waters for MRD detection in AML: flightyFLT3/ITDs

D. Gary Gilliland

View Articletitled, Murky waters for MRD detection in AML: flightyFLT3/ITDs

Epo on demand

H. Franklin Bunn

View Articletitled, Epo on demand

PLENARY PAPERS

Erythroid-specific expression of the erythropoietin receptor rescued its null mutant mice from lethality

Norio Suzuki,Osamu Ohneda,Satoru Takahashi,Masato Higuchi,Harumi Y. Mukai,Tatsutoshi Nakahata,Shigehiko Imagawa,Masayuki Yamamoto

View Articletitled, Erythroid-specific expression of the erythropoietin receptor rescued its null mutant mice from lethality

Inherited predisposition to CLL is detectable as subclinical monoclonal B-lymphocyte expansion

Andy C. Rawstron,Martin R. Yuille,Julie Fuller,Matthew Cullen,Ben Kennedy,Stephen J. Richards,Andrew S. Jack,Estella Matutes,Daniel Catovsky,Peter Hillmen,Richard S. Houlston

View Articletitled, Inherited predisposition to CLL is detectable as subclinical monoclonal B-lymphocyte expansion

ERRATA

Erratum for vol. 100, p. 1404

View Articletitled, Erratum for vol. 100, p. 1404

REVIEW ARTICLES

The World Health Organization (WHO) classification of the myeloid neoplasms
Clinical Trials & Observations

James W. Vardiman,Nancy Lee Harris,Richard D. Brunning

View Articletitled, The World Health Organization (WHO) classification of the myeloid neoplasms

Use of epoetin in patients with cancer: evidence-based clinical practice guidelines of the American Society of Clinical Oncology and the American Society of Hematology

J. Douglas Rizzo,Alan E. Lichtin,Steven H. Woolf,Jerome Seidenfeld,Charles L. Bennett,David Cella,Benjamin Djulbegovic,Matthew J. Goode,Ann A. Jakubowski,Stephanie J. Lee,Carole B. Miller,Mark U. Rarick,David H. Regan,George P. Browman,Michael S. Gordon

View Articletitled, Use of epoetin in patients with cancer: evidence-based clinical practice guidelines of the American Society of Clinical Oncology and the American Society of Hematology

CHEMOKINES

CCR5-binding chemokines modulate CXCL12 (SDF-1)–induced responses of progenitor B cells in human bone marrow through heterologous desensitization of the CXCR4 chemokine receptor

Marek Honczarenko,Yi Le,Aleksandra M. Glodek,Marcin Majka,James J. Campbell,Mariusz Z. Ratajczak,Leslie E. Silberstein

View Articletitled, CCR5-binding chemokines modulate CXCL12 (SDF-1)–induced responses of progenitor B cells in human bone marrow through heterologous desensitization of the CXCR4 chemokine receptor

Transgenic overexpression of human IL-17E results in eosinophilia, B-lymphocyte hyperplasia, and altered antibody production

Mee Rhan Kim,Raffi Manoukian,Richard Yeh,Scott M. Silbiger,Dimitry M. Danilenko,Sheila Scully,Jilin Sun,Margaret L. DeRose,Marina Stolina,David Chang,Gwyneth Y. Van,Kristie Clarkin,Hung Q. Nguyen,Yan Bin Yu,Shuqian Jing,Giorgio Senaldi,Gary Elliott,Eugene S. Medlock

View Articletitled, Transgenic overexpression of human IL-17E results in eosinophilia, B-lymphocyte hyperplasia, and altered antibody production

CLINICAL OBSERVATIONS, INTERVENTIONS, AND THERAPEUTIC TRIALS

Successful treatment of posttransplantation lymphoproliferative disorder (PTLD) following renal allografting is associated with sustained CD8⁺ T-cell restoration
Clinical Trials & Observations

Pierluigi Porcu,Charles F. Eisenbeis,Ronald P. Pelletier,Elizabeth A. Davies,Robert A. Baiocchi,Sameek Roychowdhury,Srinivas Vourganti,Gerard J. Nuovo,William L. Marsh,Amy K. Ferketich,Mitchell L. Henry,Ronald M. Ferguson,Michael A. Caligiuri

View Articletitled, Successful treatment of posttransplantation lymphoproliferative disorder (PTLD) following renal allografting is associated with sustained CD8+ T-cell restoration

Immunophenotypic clustering of myelodysplastic syndromes
Clinical Trials & Observations

Marc Maynadié,Françoise Picard,Bernard Husson,Bernard Chatelain,Yvan Cornet,Geneviève Le Roux,Lydia Campos,Alex Dromelet,Pascalle Lepelley,Hélène Jouault,Michèle Imbert,Michelle Rosenwadj,Véronique Vergé,Philippe Bissières,Martine Raphaël,Marie Christine Béné,Jean Feuillard,the Groupe d'Etude Immunologique des Leucémies (GEIL)

View Articletitled, Immunophenotypic clustering of myelodysplastic syndromes

Outcome of treatment in adults with Philadelphia chromosome–positive acute lymphoblastic leukemia—results of the prospective multicenter LALA-94 trial
Clinical Trials & Observations

Hervé Dombret,Jean Gabert,Jean-Michel Boiron,Françoise Rigal-Huguet,Didier Blaise,Xavier Thomas,André Delannoy,Agnès Buzyn,Chrystèle Bilhou-Nabera,Jean-Michel Cayuela,Pierre Fenaux,Jean-Henri Bourhis,Nathalie Fegueux,Christiane Charrin,Claude Boucheix,Véronique Lhéritier,Hélène Espérou,Elizabeth MacIntyre,Jean-Paul Vernant,Denis Fière,for the Groupe d'Etude et de Traitement de la Leucémie Aiguë Lymphoblastique de l'Adulte (GET-LALA Group)

View Articletitled, Outcome of treatment in adults with Philadelphia chromosome–positive acute lymphoblastic leukemia—results of the prospective multicenter LALA-94 trial

Treatment of hemophagocytic lymphohistiocytosis with HLH-94 immunochemotherapy and bone marrow transplantation
Clinical Trials & Observations

Jan-Inge Henter,AnnaCarin Samuelsson-Horne,Maurizio Aricò,R. Maarten Egeler,Göran Elinder,Alexandra H. Filipovich,Helmut Gadner,Shinsaku Imashuku,Diane Komp,Stephan Ladisch,David Webb,Gritta Janka,for the Histiocyte Society

View Articletitled, Treatment of hemophagocytic lymphohistiocytosis with HLH-94 immunochemotherapy and bone marrow transplantation

Current trends in hematopoietic stem cell transplantation in Europe
Clinical Trials & Observations

Alois Gratwohl,Helen Baldomero,Bruno Horisberger,Caroline Schmid,Jakob Passweg,Alvaro Urbano-Ispizua,for the Accreditation Committee of the European Group for Blood and Marrow Transplantation (EBMT)

View Articletitled, Current trends in hematopoietic stem cell transplantation in Europe

Internal tandem duplication of FLT3 in relapsed acute myeloid leukemia: a comparative analysis of bone marrow samples from 108 adult patients at diagnosis and relapse
Clinical Trials & Observations

Lee-Yung Shih,Chein-Fuang Huang,Jin-Hou Wu,Tung-Liang Lin,Po Dunn,Po-Nan Wang,Ming-Chung Kuo,Chang-Liang Lai,Hui-Chin Hsu

View Articletitled, Internal tandem duplication of FLT3 in relapsed acute myeloid leukemia: a comparative analysis of bone marrow samples from 108 adult patients at diagnosis and relapse

Studies of FLT3 mutations in paired presentation and relapse samples from patients with acute myeloid leukemia: implications for the role of FLT3 mutations in leukemogenesis, minimal residual disease detection, and possible therapy with FLT3 inhibitors
Clinical Trials & Observations

Panagiotis D. Kottaridis,Rosemary E. Gale,Stephen E. Langabeer,Marion E. Frew,David T. Bowen,David C. Linch

View Articletitled, Studies of FLT3 mutations in paired presentation and relapse samples from patients with acute myeloid leukemia: implications for the role of FLT3 mutations in leukemogenesis, minimal residual disease detection, and possible therapy with FLT3 inhibitors

Use of peripheral blood instead of bone marrow to monitor residual disease in children with acute lymphoblastic leukemia
Clinical Trials & Observations

Elaine Coustan-Smith,Jose Sancho,Michael L. Hancock,Bassem I. Razzouk,Raul C. Ribeiro,Gaston K. Rivera,Jeffrey E. Rubnitz,John T. Sandlund,Ching-Hon Pui,Dario Campana

View Articletitled, Use of peripheral blood instead of bone marrow to monitor residual disease in children with acute lymphoblastic leukemia

The incidence of venous thromboembolism in thrombophilic children: a prospective cohort study
Clinical Trials & Observations

Daniela Tormene,Paolo Simioni,Paolo Prandoni,Francesca Franz,Patrizia Zerbinati,Giulio Tognin,Antonio Girolami

View Articletitled, The incidence of venous thromboembolism in thrombophilic children: a prospective cohort study

GENE THERAPY

Long-term reversal of chronic anemia using a hypoxia-regulated erythropoietin gene therapy

Katie Binley,Zoe Askham,Sharifah Iqball,Hayley Spearman,Leigh Martin,Mahesh de Alwis,Adrian J. Thrasher,Robin R. Ali,Patrick H. Maxwell,Susan Kingsman,Stuart Naylor

View Articletitled, Long-term reversal of chronic anemia using a hypoxia-regulated erythropoietin gene therapy

HEMATOPOIESIS

S-phase–specific interaction of the Fanconi anemia protein, FANCD2, with BRCA1 and RAD51

Toshiyasu Taniguchi,Irene Garcia-Higuera,Paul R. Andreassen,Richard C. Gregory,Markus Grompe,Alan D. D'Andrea

View Articletitled, S-phase–specific interaction of the Fanconi anemia protein, FANCD2, with BRCA1 and RAD51

Tumor necrosis factor–related apoptosis-inducing ligand induces monocytic maturation of leukemic and normal myeloid precursors through a caspase-dependent pathway

Paola Secchiero,Arianna Gonelli,Prisco Mirandola,Elisabetta Melloni,Loris Zamai,Claudio Celeghini,Daniela Milani,Giorgio Zauli

View Articletitled, Tumor necrosis factor–related apoptosis-inducing ligand induces monocytic maturation of leukemic and normal myeloid precursors through a caspase-dependent pathway

The SCL complex regulates c-kit expression in hematopoietic cells through functional interaction with Sp1

Eric Lécuyer,Sabine Herblot,Marianne Saint-Denis,Richard Martin,C. Glenn Begley,Catherine Porcher,Stuart H. Orkin,Trang Hoang

View Articletitled, The SCL complex regulates c-kit expression in hematopoietic cells through functional interaction with Sp1

Biochemical characterization of PRV-1, a novel hematopoietic cell surface receptor, which is overexpressed in polycythemia rubra vera

Steffen Klippel,Elisabeth Strunck,Christian E. Busse,Dirk Behringer,Heike L. Pahl

View Articletitled, Biochemical characterization of PRV-1, a novel hematopoietic cell surface receptor, which is overexpressed in polycythemia rubra vera

Role of Cbfb in hematopoiesis and perturbations resulting from expression of the leukemogenic fusion gene Cbfb-MYH11

Mondira Kundu,Amy Chen,Stacie Anderson,Martha Kirby,LiPing Xu,Lucio H. Castilla,David Bodine,Pu Paul Liu

View Articletitled, Role of Cbfb in hematopoiesis and perturbations resulting from expression of the leukemogenic fusion gene Cbfb-MYH11

The Fanconi anemia protein, FANCE, promotes the nuclear accumulation of FANCC

Toshiyasu Taniguchi,Alan D. D'Andrea

View Articletitled, The Fanconi anemia protein, FANCE, promotes the nuclear accumulation of FANCC

The antiapoptosis protein survivin is associated with cell cycle entry of normal cord blood CD34⁺ cells and modulates cell cycle and proliferation of mouse hematopoietic progenitor cells

Seiji Fukuda,Richard G. Foster,Scott B. Porter,Louis M. Pelus

View Articletitled, The antiapoptosis protein survivin is associated with cell cycle entry of normal cord blood CD34+ cells and modulates cell cycle and proliferation of mouse hematopoietic progenitor cells

HEMOSTASIS, THROMBOSIS, AND VASCULAR BIOLOGY

Sustained integrin ligation involves extracellular free sulfhydryls and enzymatically catalyzed disulfide exchange

Judith Lahav,Kerstin Jurk,Oded Hess,Michael J. Barnes,Richard W. Farndale,Jacob Luboshitz,Beate E. Kehrel

View Articletitled, Sustained integrin ligation involves extracellular free sulfhydryls and enzymatically catalyzed disulfide exchange

Junctional adhesion molecule-2 (JAM-2) promotes lymphocyte transendothelial migration

Caroline A. Johnson-Léger,Michel Aurrand-Lions,Nicola Beltraminelli,Nicolas Fasel,Beat A. Imhof

View Articletitled, Junctional adhesion molecule-2 (JAM-2) promotes lymphocyte transendothelial migration

Lack of α2-antiplasmin promotes pulmonary heart failure via overrelease of VEGF after acute myocardial infarction

Hiroyuki Matsuno,Osamu Kozawa,Naoki Yoshimi,Shigeru Akamatsu,Akira Hara,Hideki Mori,Kiyotaka Okada,Shigeru Ueshima,Osamu Matsuo,Toshihiko Uematsu

View Articletitled, Lack of α2-antiplasmin promotes pulmonary heart failure via overrelease of VEGF after acute myocardial infarction

Hemin induces neuroglobin expression in neural cells

Yonghua Zhu,Yunjuan Sun,Kunlin Jin,David A. Greenberg

View Articletitled, Hemin induces neuroglobin expression in neural cells

P2X₁-mediated activation of extracellular signal-regulated kinase 2 contributes to platelet secretion and aggregation induced by collagen

Cécile Oury,Emese Toth-Zsamboki,Jos Vermylen,Marc F. Hoylaerts

View Articletitled, P2X1-mediated activation of extracellular signal-regulated kinase 2 contributes to platelet secretion and aggregation induced by collagen

Evidence that α-synuclein functions as a negative regulator of Ca⁺⁺-dependent α-granule release from human platelets

Sang Myun Park,Han Young Jung,Hyun Ok Kim,Hyangshuk Rhim,Seung R. Paik,Kwang Chul Chung,Jeon Han Park,Jongsun Kim

View Articletitled, Evidence that α-synuclein functions as a negative regulator of Ca++-dependent α-granule release from human platelets

Molecular basis of quantitative factor V deficiency associated with factor V R2 haplotype

Tomio Yamazaki,Gerry A. F. Nicolaes,Kristoffer W. Sørensen,Björn Dahlbäck

View Articletitled, Molecular basis of quantitative factor V deficiency associated with factor V R2 haplotype

Biphasic transmittance waveform in the APTT coagulation assay is due to the formation of a Ca⁺⁺-dependent complex of C-reactive protein with very-low–density lipoprotein and is a novel marker of impending disseminated intravascular coagulation
Clinical Trials & Observations

Cheng Hock Toh,John Samis,Colin Downey,John Walker,Lev Becker,Nicole Brufatto,Liliana Tejidor,Greg Jones,Wim Houdijk,Alan Giles,Marlys Koschinsky,Larry O. Ticknor,Ray Paton,Richard Wenstone,Michael Nesheim

View Articletitled, Biphasic transmittance waveform in the APTT coagulation assay is due to the formation of a Ca++-dependent complex of C-reactive protein with very-low–density lipoprotein and is a novel marker of impending disseminated intravascular coagulation

Heparin acts synergistically with interleukin-11 to induce STAT3 activation and in vitro osteoclast formation

Kimberly J. Walton,Joanne M. Duncan,Paula Deschamps,Stephen G. Shaughnessy

View Articletitled, Heparin acts synergistically with interleukin-11 to induce STAT3 activation and in vitro osteoclast formation

IMMUNOBIOLOGY

Creating space: an antigen-independent, CpG-induced peripheral expansion of naive and memory T lymphocytes in a full T-cell compartment

Eduardo Davila,Maria G. Velez,Carrie J. Heppelmann,Esteban Celis

View Articletitled, Creating space: an antigen-independent, CpG-induced peripheral expansion of naive and memory T lymphocytes in a full T-cell compartment

gp120-mediated induction of the MAPK cascade is dependent on the activation state of CD4⁺ lymphocytes

Sandrina Kinet,Fréderic Bernard,Cédric Mongellaz,Matthieu Perreau,Frederick D. Goldman,Naomi Taylor

View Articletitled, gp120-mediated induction of the MAPK cascade is dependent on the activation state of CD4+ lymphocytes

Dendritic cells for NK/LAK activation: rationale for multicellular immunotherapy in neuroblastoma patients

Dominique Valteau-Couanet,Christophe Leboulaire,Kim Maincent,Muriel Tournier,Olivier Hartmann,Jean Bénard,Françoise Beaujean,Catherine Boccaccio,Laurence Zitvogel,Eric Angevin

View Articletitled, Dendritic cells for NK/LAK activation: rationale for multicellular immunotherapy in neuroblastoma patients

Role for granulocyte colony–stimulating factor in the generation of human T regulatory type 1 cells

Sergio Rutella,Luca Pierelli,Giuseppina Bonanno,Simona Sica,Franco Ameglio,Ettore Capoluongo,Andrea Mariotti,Giovanni Scambia,Giuseppe d'Onofrio,Giuseppe Leone

View Articletitled, Role for granulocyte colony–stimulating factor in the generation of human T regulatory type 1 cells

NEOPLASIA

Aberrant DNA methylation ofp57^KIP2 gene in the promoter region in lymphoid malignancies of B-cell phenotype

Yinghua Li,Hirokazu Nagai,Toshihito Ohno,Masaaki Yuge,Sonoko Hatano,Etsuro Ito,Naoyoshi Mori,Hidehiko Saito,Tomohiro Kinoshita

View Articletitled, Aberrant DNA methylation ofp57KIP2 gene in the promoter region in lymphoid malignancies of B-cell phenotype

Characterization of hyaluronan synthase expression and hyaluronan synthesis in bone marrow mesenchymal progenitor cells: predominant expression of HAS1 mRNA and up-regulated hyaluronan synthesis in bone marrow cells derived from multiple myeloma patients

Anthony Calabro,Martin M. Oken,Vincent C. Hascall,Anna M. Masellis

View Articletitled, Characterization of hyaluronan synthase expression and hyaluronan synthesis in bone marrow mesenchymal progenitor cells: predominant expression of HAS1 mRNA and up-regulated hyaluronan synthesis in bone marrow cells derived from multiple myeloma patients

Response to histone deacetylase inhibition of novel PML/RARα mutants detected in retinoic acid–resistant APL cells

Sylvie Côté,Angelika Rosenauer,Andrea Bianchini,Karen Seiter,Jonathan Vandewiele,Clara Nervi,Wilson H. Miller, Jr

View Articletitled, Response to histone deacetylase inhibition of novel PML/RARα mutants detected in retinoic acid–resistant APL cells

CXCR4–SDF-1 signaling is active in rhabdomyosarcoma cells and regulates locomotion, chemotaxis, and adhesion: Presented at the Annual Meeting of the American Society of Hematology, Orlando, FL, December 7-11, 2001.

Jolanta Libura,Justyna Drukala,Marcin Majka,Oana Tomescu,Jean Marc Navenot,Magda Kucia,Leah Marquez,Stephen C. Peiper,Frederic G. Barr,Anna Janowska-Wieczorek,Mariusz Z. Ratajczak

View Articletitled, CXCR4–SDF-1 signaling is active in rhabdomyosarcoma cells and regulates locomotion, chemotaxis, and adhesion: Presented at the Annual Meeting of the American Society of Hematology, Orlando, FL, December 7-11, 2001.

PHAGOCYTES

Role of PI3-kinase–dependent Bad phosphorylation and altered transcription in cytokine-mediated neutrophil survival

Andrew S. Cowburn,Karen A. Cadwallader,Benjamin J. Reed,Neda Farahi,Edwin R. Chilvers

View Articletitled, Role of PI3-kinase–dependent Bad phosphorylation and altered transcription in cytokine-mediated neutrophil survival

Iron transporter Nramp2/DMT-1 is associated with the membrane of phagosomes in macrophages and Sertoli cells

Nada Jabado,François Canonne-Hergaux,Samantha Gruenheid,Virgine Picard,Philippe Gros

View Articletitled, Iron transporter Nramp2/DMT-1 is associated with the membrane of phagosomes in macrophages and Sertoli cells

RED CELLS

Hypoxia-inducible erythropoietin gene expression in human neuroblastoma cells

Ineke Stolze,Utta Berchner-Pfannschmidt,Patricia Freitag,Christoph Wotzlaw,Jochen Rössler,Stilla Frede,Helmut Acker,Joachim Fandrey

View Articletitled, Hypoxia-inducible erythropoietin gene expression in human neuroblastoma cells

A splicing alteration of 4.1R pre-mRNA generates 2 protein isoforms with distinct assembly to spindle poles in mitotic cells

François Delhommeau,Corinne Vasseur-Godbillon,Philippe Leclerc,Pierre-Olivier Schischmanoff,Laure Croisille,Patricia Rince,Madeleine Morinière,Edward J. Benz, Jr,Gil Tchernia,Gabriel Tamagnini,Leticia Ribeiro,Jean Delaunay,Faouzi Baklouti

View Articletitled, A splicing alteration of 4.1R pre-mRNA generates 2 protein isoforms with distinct assembly to spindle poles in mitotic cells

TRANSFUSION MEDICINE

Frequency and load of hepatitis B virus DNA in first-time blood donors with antibodies to hepatitis B core antigen

Holger Hennig,Ines Puchta,Jürgen Luhm,Peter Schlenke,Siegfried Goerg,Holger Kirchner

View Articletitled, Frequency and load of hepatitis B virus DNA in first-time blood donors with antibodies to hepatitis B core antigen

TRANSPLANTATION

Interleukin 7 worsens graft-versus-host disease

Manoj L. Sinha,Terry J. Fry,Daniel H. Fowler,Georgina Miller,Crystal L. Mackall

View Articletitled, Interleukin 7 worsens graft-versus-host disease

Cytokine and chemokine profiles in autologous graft-versus-host disease (GVHD): interleukin 10 and interferon γ may be critical mediators for the development of autologous GVHD

Yuji Miura,Christopher J. Thoburn,Emilie C. Bright,Weiran Chen,Shinji Nakao,Allan D. Hess

View Articletitled, Cytokine and chemokine profiles in autologous graft-versus-host disease (GVHD): interleukin 10 and interferon γ may be critical mediators for the development of autologous GVHD

BRIEF REPORTS

V_H gene analysis of splenic marginal zone lymphomas reveals diversity in mutational status and initiation of somatic mutation in vivo
Brief Report

Delin Zhu,Jennifer Orchard,David G. Oscier,Dennis H. Wright,Freda K. Stevenson

View Articletitled, VH gene analysis of splenic marginal zone lymphomas reveals diversity in mutational status and initiation of somatic mutation in vivo

Placental/umbilical cord blood for unrelated-donor bone marrow reconstitution: relevance of nucleated red blood cells
Clinical Trials & Observations Brief Report

Cladd E. Stevens,Jessica Gladstone,Patricia E. Taylor,Andromachi Scaradavou,Anna Rita Migliaccio,Jan Visser,N. Ludy Dobrila,Carmelita Carrier,Michael Cabbad,Peter Wernet,Joanne Kurtzberg,Pablo Rubinstein

View Articletitled, Placental/umbilical cord blood for unrelated-donor bone marrow reconstitution: relevance of nucleated red blood cells

Evidence that the number of hematopoietic stem cells per animal is conserved in mammals
Brief Report

Janis L. Abkowitz,Sandra N. Catlin,Monica T. McCallie,Peter Guttorp

View Articletitled, Evidence that the number of hematopoietic stem cells per animal is conserved in mammals

Phagocytosing neutrophils down-regulate the expression of chemokine receptors CXCR1 and CXCR2
Brief Report

Tatyana Doroshenko,Yuri Chaly,Valery Savitskiy,Olga Maslakova,Anna Portyanko,Irina Gorudko,Nikolai N. Voitenok

View Articletitled, Phagocytosing neutrophils down-regulate the expression of chemokine receptors CXCR1 and CXCR2

CORRESPONDENCE

Rituximab-induced tumor cell agglutination

Muttuswamy Sivakumaran

View Articletitled, Rituximab-induced tumor cell agglutination

Prognostic factors for acute graft-versus-host disease after donor lymphocyte infusions

Francesco Dazzi,Richard M. Szydlo,Jane F. Apperley,John M. Goldman

View Articletitled, Prognostic factors for acute graft-versus-host disease after donor lymphocyte infusions

Chimerism induction and delayed onset of cytomegalovirus (CMV) infection after allogeneic reduced-intensity stem cell transplantation (RIST)

Kunihisa Nakai,Shin Mineishi,Masahiro Kami,Yoshinobu Kanda,Ryuji Tanosaki,Yoichi Takaue

View Articletitled, Chimerism induction and delayed onset of cytomegalovirus (CMV) infection after allogeneic reduced-intensity stem cell transplantation (RIST)

Warfarin treatment of a patient with coagulation factor IX propeptide mutation causing warfarin hypersensitivity

Søren Risom Kristensen

View Articletitled, Warfarin treatment of a patient with coagulation factor IX propeptide mutation causing warfarin hypersensitivity

Is hemophagocytic lymphohistiocytosis an autoimmune disease?

Volker Schuster,Friedemann Horn,Michael Borte

View Articletitled, Is hemophagocytic lymphohistiocytosis an autoimmune disease?

Autoimmunity in severe combined immunodeficiency (SCID)

Ronit Elhasid,Reuven Bergman,Amos Etzioni

View Articletitled, Autoimmunity in severe combined immunodeficiency (SCID)

Long-term follow-up on a patient with incomplete POEMS syndrome undergoing high-dose therapy and autologous blood stem cell transplantation

Anne Wiesmann,Robert Weissert,Lothar Kanz,Hermann Einsele

View Articletitled, Long-term follow-up on a patient with incomplete POEMS syndrome undergoing high-dose therapy and autologous blood stem cell transplantation

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Issue Archive

Table of Contents

INSIDE BLOOD

PLENARY PAPERS

ERRATA

REVIEW ARTICLES

The World Health Organization (WHO) classification of the myeloid neoplasms Clinical Trials & Observations

CHEMOKINES

CLINICAL OBSERVATIONS, INTERVENTIONS, AND THERAPEUTIC TRIALS

Successful treatment of posttransplantation lymphoproliferative disorder (PTLD) following renal allografting is associated with sustained CD8+ T-cell restoration Clinical Trials & Observations

Immunophenotypic clustering of myelodysplastic syndromes Clinical Trials & Observations

Outcome of treatment in adults with Philadelphia chromosome–positive acute lymphoblastic leukemia—results of the prospective multicenter LALA-94 trial Clinical Trials & Observations

Treatment of hemophagocytic lymphohistiocytosis with HLH-94 immunochemotherapy and bone marrow transplantation Clinical Trials & Observations

Current trends in hematopoietic stem cell transplantation in Europe Clinical Trials & Observations

Internal tandem duplication of FLT3 in relapsed acute myeloid leukemia: a comparative analysis of bone marrow samples from 108 adult patients at diagnosis and relapse Clinical Trials & Observations

Studies of FLT3 mutations in paired presentation and relapse samples from patients with acute myeloid leukemia: implications for the role of FLT3 mutations in leukemogenesis, minimal residual disease detection, and possible therapy with FLT3 inhibitors Clinical Trials & Observations

Use of peripheral blood instead of bone marrow to monitor residual disease in children with acute lymphoblastic leukemia Clinical Trials & Observations

The incidence of venous thromboembolism in thrombophilic children: a prospective cohort study Clinical Trials & Observations