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Volume 100, Issue 6

September 15 2002

In this Issue

INSIDE BLOOD
REVIEW ARTICLES
CHEMOKINES
CLINICAL OBSERVATIONS, INTERVENTIONS, AND THERAPEUTIC TRIALS
GENE THERAPY
HEMATOPOIESIS
HEMOSTASIS, THROMBOSIS, AND VASCULAR BIOLOGY
IMMUNOBIOLOGY
NEOPLASIA
PHAGOCYTES
RED CELLS
TRANSPLANTATION
BRIEF REPORTS
CORRESPONDENCE

INSIDE BLOOD

Starting out right: Kozak sequences and clots

Ellis Neufeld

View Articletitled, Starting out right: Kozak sequences and clots

The mechanism of action of high-dose IgG in idiopathic thrombocytopenic purpura

John G. Kelton

View Articletitled, The mechanism of action of high-dose IgG in idiopathic thrombocytopenic purpura

REVIEW ARTICLES

Natural killer cell receptors: new biology and insights into the graft-versus-leukemia effect

Sherif S. Farag,Todd A. Fehniger,Loredana Ruggeri,Andrea Velardi,Michael A. Caligiuri

View Articletitled, Natural killer cell receptors: new biology and insights into the graft-versus-leukemia effect

CHEMOKINES

CCL19 induces rapid dendritic extension of murine dendritic cells

Yoshiki Yanagawa,Kazunori Onoé

View Articletitled, CCL19 induces rapid dendritic extension of murine dendritic cells

CLINICAL OBSERVATIONS, INTERVENTIONS, AND THERAPEUTIC TRIALS

Racial and ethnic differences in survival of children with acute lymphoblastic leukemia
Clinical Trials & Observations

Smita Bhatia,Harland N. Sather,Nyla A. Heerema,Michael E. Trigg,Paul S. Gaynon,Leslie L. Robison

View Articletitled, Racial and ethnic differences in survival of children with acute lymphoblastic leukemia

A phase 2 study of imatinib in patients with relapsed or refractory Philadelphia chromosome–positive acute lymphoid leukemias
Clinical Trials & Observations

Oliver G. Ottmann,Brian J. Druker,Charles L. Sawyers,John M. Goldman,Jose Reiffers,Richard T. Silver,Sante Tura,Thomas Fischer,Michael W. Deininger,Charles A. Schiffer,Michele Baccarani,Alois Gratwohl,Andreas Hochhaus,Dieter Hoelzer,Sofia Fernandes-Reese,Insa Gathmann,Renaud Capdeville,Stephen G. O'Brien

View Articletitled, A phase 2 study of imatinib in patients with relapsed or refractory Philadelphia chromosome–positive acute lymphoid leukemias

Clinicobiological features and outcome of acute promyelocytic leukemia occurring as a second tumor: the GIMEMA experience
Clinical Trials & Observations

Alessandro Pulsoni,Livio Pagano,Francesco Lo Coco,Giuseppe Avvisati,Luca Mele,Eros Di Bona,Rosangela Invernizzi,Franco Leoni,Filippo Marmont,Alfonso Mele,Lorella Melillo,Anna Maria Nosari,Enrico Maria Pogliani,Marco Vignetti,Giuseppe Visani,Vittorina Zagonel,Giuseppe Leone,Franco Mandelli

View Articletitled, Clinicobiological features and outcome of acute promyelocytic leukemia occurring as a second tumor: the GIMEMA experience

Ursodeoxycholic acid for the prevention of hepatic complications in allogeneic stem cell transplantation
Clinical Trials & Observations

Tapani Ruutu,Britta Eriksson,Kari Remes,Eeva Juvonen,Liisa Volin,Mats Remberger,Terttu Parkkali,Hans Hägglund,Olle Ringdén,for the Nordic Bone Marrow Transplantation Group

View Articletitled, Ursodeoxycholic acid for the prevention of hepatic complications in allogeneic stem cell transplantation

Stanford V regimen and concomitant HAART in 59 patients with Hodgkin disease and HIV infection
Clinical Trials & Observations

Michele Spina,Jean Gabarre,Giuseppe Rossi,Marco Fasan,Clara Schiantarelli,Ezio Nigra,Maurizio Mena,Andrea Antinori,Adriana Ammassari,Renato Talamini,Emanuela Vaccher,Giampiero di Gennaro,Umberto Tirelli

View Articletitled, Stanford V regimen and concomitant HAART in 59 patients with Hodgkin disease and HIV infection

Second malignancy after Hodgkin disease treated with radiation therapy with or without chemotherapy: long-term risks and risk factors
Clinical Trials & Observations

Andrea K. Ng,M. V. Patricia Bernardo,Edie Weller,Kendall Backstrand,Barbara Silver,Karen C. Marcus,Nancy J. Tarbell,Mary Ann Stevenson,Jonathan W. Friedberg,Peter M. Mauch

View Articletitled, Second malignancy after Hodgkin disease treated with radiation therapy with or without chemotherapy: long-term risks and risk factors

Bone marrow transplantation from HLA-identical siblings as treatment for myelodysplasia
Clinical Trials & Observations

Jorge Sierra,Waleska S. Pérez,Ciril Rozman,Enric Carreras,John P. Klein,J. Douglas Rizzo,Stella M. Davies,Hillard M. Lazarus,Christopher N. Bredeson,David I. Marks,Carmen Canals,Marc A. Boogaerts,John Goldman,Richard E. Champlin,Armand Keating,Daniel J. Weisdorf,Theo M. de Witte,Mary M. Horowitz

View Articletitled, Bone marrow transplantation from HLA-identical siblings as treatment for myelodysplasia

High incidence of human herpesvirus 6 infection with a high viral load in cord blood stem cell transplant recipients
Clinical Trials & Observations

Junji Sashihara,Keiko Tanaka-Taya,Shinya Tanaka,Kiyoko Amo,Hiromi Miyagawa,Gaku Hosoi,Tomokuni Taniguchi,Takafumi Fukui,Naoki Kasuga,Toshiya Aono,Masahiro Sako,Junichi Hara,Koichi Yamanishi,Shintaro Okada

View Articletitled, High incidence of human herpesvirus 6 infection with a high viral load in cord blood stem cell transplant recipients

GENE THERAPY

Development of virus vectors for gene therapy of β chain hemoglobinopathies: flanking with a chromatin insulator reduces γ-globin gene silencing in vivo

David W. Emery,Evangelia Yannaki,Julie Tubb,Tamon Nishino,Qiliang Li,George Stamatoyannopoulos

View Articletitled, Development of virus vectors for gene therapy of β chain hemoglobinopathies: flanking with a chromatin insulator reduces γ-globin gene silencing in vivo

Graft-versus-leukemia effect after suicide-gene–mediated control of graft-versus-host disease

Elena Litvinova,Sébastien Maury,Olivier Boyer,Sylvie Bruel,Laurent Benard,Gilbert Boisserie,David Klatzmann,José L. Cohen

View Articletitled, Graft-versus-leukemia effect after suicide-gene–mediated control of graft-versus-host disease

Pharmacologically regulated in vivo selection in a large animal

Tobias Neff,Peter A. Horn,Victor E. Valli,Allen M. Gown,Scott Wardwell,Brent L. Wood,Christof von Kalle,Manfred Schmidt,Laura J. Peterson,Julia C. Morris,Robert E. Richard,Tim Clackson,Hans-Peter Kiem,C. Anthony Blau

View Articletitled, Pharmacologically regulated in vivo selection in a large animal

In vitro phenotypic correction of hematopoietic progenitors from Fanconi anemia group A knockout mice

Paula Rı́o,José Carlos Segovia,Helmut Hanenberg,JoséAntonio Casado,Jesús Martı́nez,Kerstin Göttsche,Ngan Ching Cheng,Henri J. Van de Vrugt,Fré Arwert,Hans Joenje,Juan A. Bueren

View Articletitled, In vitro phenotypic correction of hematopoietic progenitors from Fanconi anemia group A knockout mice

HEMATOPOIESIS

X-linked thrombocytopenia with thalassemia from a mutation in the amino finger of GATA-1 affecting DNA binding rather than FOG-1 interaction

Channing Yu,Kathy K. Niakan,Mark Matsushita,George Stamatoyannopoulos,Stuart H. Orkin,Wendy H. Raskind

View Articletitled, X-linked thrombocytopenia with thalassemia from a mutation in the amino finger of GATA-1 affecting DNA binding rather than FOG-1 interaction

Ectopic expression of Delta4 impairs hematopoietic development and leads to lymphoproliferative disease

Marion Dorsch,Gang Zheng,David Yowe,Prakash Rao,Yanjun Wang,Qiong Shen,Curran Murphy,Ximing Xiong,Qiuju Shi,Jose-Carlos Gutierrez-Ramos,Chris Fraser,Jean-Luc Villeval

View Articletitled, Ectopic expression of Delta4 impairs hematopoietic development and leads to lymphoproliferative disease

A genetic and genomic analysis identifies a cluster of genes associated with hematopoietic cell turnover

Gerald de Haan,Leonid V. Bystrykh,Ellen Weersing,Bert Dontje,Hartmut Geiger,Natalia Ivanova,Ihor R. Lemischka,Edo Vellenga,Gary Van Zant

View Articletitled, A genetic and genomic analysis identifies a cluster of genes associated with hematopoietic cell turnover

The cytoplasmic domain of Mpl receptor transduces exclusive signals in embryonic and fetal hematopoietic cells

Cécile Challier,Laurence Cocault,Rolande Berthier,Nadine Binart,Isabelle Dusanter-Fourt,Georges Uzan,Michèle Souyri

View Articletitled, The cytoplasmic domain of Mpl receptor transduces exclusive signals in embryonic and fetal hematopoietic cells

HEMOSTASIS, THROMBOSIS, AND VASCULAR BIOLOGY

Acute thrombocytopenia after treatment with tirofiban or eptifibatide is associated with antibodies specific for ligand-occupied GPIIb/IIIa

Daniel W. Bougie,Peter R. Wilker,Elizabeth D. Wuitschick,Brian R. Curtis,Mohammad Malik,Stewart Levine,Richard N. Lind,Jaime Pereira,Richard H. Aster

View Articletitled, Acute thrombocytopenia after treatment with tirofiban or eptifibatide is associated with antibodies specific for ligand-occupied GPIIb/IIIa

The caspase inhibitor z-VAD is more effective than CD18 adhesion blockade in reducing muscle ischemia-reperfusion injury: implication for clinical trials

Akiko Iwata,John M. Harlan,Nicholas B. Vedder,Robert K. Winn

View Articletitled, The caspase inhibitor z-VAD is more effective than CD18 adhesion blockade in reducing muscle ischemia-reperfusion injury: implication for clinical trials

A common polymorphism in the annexin V Kozak sequence (−1C>T) increases translation efficiency and plasma levels of annexin V, and decreases the risk of myocardial infarction in young patients
Clinical Trials & Observations

Rocio González-Conejero,Javier Corral,Vanessa Roldán,Constantino Martı́nez,Francisco Marı́n,José Rivera,Juan A. Iniesta,Marı́a L. Lozano,Pascual Marco,Vicente Vicente

View Articletitled, A common polymorphism in the annexin V Kozak sequence (−1C>T) increases translation efficiency and plasma levels of annexin V, and decreases the risk of myocardial infarction in young patients

Effects of intravenous immunoglobulin on platelet count and antiplatelet antibody disposition in a rat model of immune thrombocytopenia

Ryan J. Hansen,Joseph P. Balthasar

View Articletitled, Effects of intravenous immunoglobulin on platelet count and antiplatelet antibody disposition in a rat model of immune thrombocytopenia

Disruption of the long-range GPIIIa Cys₅-Cys₄₃₅ disulfide bond results in the production of constitutively active GPIIb-IIIa (α_IIbβ₃) integrin complexes

Qi-Hong Sun,Chao-Yan Liu,Ronggang Wang,Cathy Paddock,Peter J. Newman

View Articletitled, Disruption of the long-range GPIIIa Cys5-Cys435 disulfide bond results in the production of constitutively active GPIIb-IIIa (αIIbβ3) integrin complexes

Amelioration of the macrothrombocytopenia associated with the murine Bernard-Soulier syndrome

Taisuke Kanaji,Susan Russell,Jerry Ware

View Articletitled, Amelioration of the macrothrombocytopenia associated with the murine Bernard-Soulier syndrome

Effect of hyperhomocysteinemia on protein C activation and activity

Steven R. Lentz,Donald J. Piegors,José A. Fernández,Rochelle A. Erger,Erland Arning,M. René Malinow,John H. Griffin,Teodoro Bottiglieri,William G. Haynes,Donald D. Heistad

View Articletitled, Effect of hyperhomocysteinemia on protein C activation and activity

Normal Arp2/3 complex activation in platelets lacking WASp

Hervé Falet,Karin M. Hoffmeister,Ralph Neujahr,John H. Hartwig

View Articletitled, Normal Arp2/3 complex activation in platelets lacking WASp

IMMUNOBIOLOGY

Identification of tumor-associated antigens in chronic lymphocytic leukemia by SEREX

Angela M. Krackhardt,Mathias Witzens,Sabine Harig,F. Stephen Hodi,A. Jason Zauls,Morgan Chessia,Patrick Barrett,John G. Gribben

View Articletitled, Identification of tumor-associated antigens in chronic lymphocytic leukemia by SEREX

CD8 T-cell responses to Wilms tumor gene product WT1 and proteinase 3 in patients with acute myeloid leukemia

Carmen Scheibenbogen,Anne Letsch,Eckhard Thiel,Alexander Schmittel,Volker Mailaender,Steffi Baerwolf,Dirk Nagorsen,Ulrich Keilholz

View Articletitled, CD8 T-cell responses to Wilms tumor gene product WT1 and proteinase 3 in patients with acute myeloid leukemia

Regulation of FcεRI-mediated degranulation by an adaptor protein 3BP2 in rat basophilic leukemia RBL-2H3 cells

Kiyonao Sada,S. M. Shahjahan Miah,Koichiro Maeno,Shinkou Kyo,Xiujuan Qu,Hirohei Yamamura

View Articletitled, Regulation of FcεRI-mediated degranulation by an adaptor protein 3BP2 in rat basophilic leukemia RBL-2H3 cells

The immunophenotypic and immunogenotypic B-cell differentiation arrest in bone marrow of RAG-deficient SCID patients corresponds to residual recombination activities of mutated RAG proteins

Jeroen G. Noordzij,Sandra de Bruin-Versteeg,Nicole S. Verkaik,Jaak M. J. J. Vossen,Ronald de Groot,Ewa Bernatowska,Anton W. Langerak,Dik C. van Gent,Jacques J. M. van Dongen

View Articletitled, The immunophenotypic and immunogenotypic B-cell differentiation arrest in bone marrow of RAG-deficient SCID patients corresponds to residual recombination activities of mutated RAG proteins

Human fetuses are able to mount an adultlike CD8 T-cell response

Emmanuel Hermann,Carine Truyens,Cristina Alonso-Vega,Jos Even,Patricia Rodriguez,Aurélie Berthe,Eric Gonzalez-Merino,Faustino Torrico,Yves Carlier

View Articletitled, Human fetuses are able to mount an adultlike CD8 T-cell response

Long-term effects of intermittent interleukin 2 therapy in patients with HIV infection: characterization of a novel subset of CD4⁺/CD25⁺ T cells

Irini Sereti,Hector Martinez-Wilson,Julia A. Metcalf,Michael W. Baseler,Claire W. Hallahan,Barbara Hahn,Richard L. Hengel,Richard T. Davey,Joseph A. Kovacs,H. Clifford Lane

View Articletitled, Long-term effects of intermittent interleukin 2 therapy in patients with HIV infection: characterization of a novel subset of CD4+/CD25+ T cells

A prospective study on the evolution of the T-cell repertoire in patients with Sézary syndrome treated by extracorporeal photopheresis
Clinical Trials & Observations

Saskia Ingen-Housz-Oro,Annette Bussel,Béatrice Flageul,Laurence Michel,Louis Dubertret,Philippe Kourilsky,Gabriel Gachelin,Hervé Bachelez,Philippe Musette

View Articletitled, A prospective study on the evolution of the T-cell repertoire in patients with Sézary syndrome treated by extracorporeal photopheresis

NEOPLASIA

A molecular compendium of genes expressed in multiple myeloma

Jaime O. Claudio,Esther Masih-Khan,Hongchang Tang,Jason Gonçalves,Michael Voralia,Zhi Hua Li,Vincent Nadeem,Eva Cukerman,Ofelia Francisco-Pabalan,Choong Chin Liew,James R. Woodgett,A. Keith Stewart

View Articletitled, A molecular compendium of genes expressed in multiple myeloma

2-Methoxyestradiol overcomes drug resistance in multiple myeloma cells

Dharminder Chauhan,Laurence Catley,Teru Hideshima,Guilan Li,Richard Leblanc,Deepak Gupta,Martin Sattler,Paul Richardson,Robert L. Schlossman,Klaus Podar,Edie Weller,Nikhil Munshi,Kenneth C. Anderson

View Articletitled, 2-Methoxyestradiol overcomes drug resistance in multiple myeloma cells

Role for macrophage inflammatory protein (MIP)-1α and MIP-1β in the development of osteolytic lesions in multiple myeloma

Masahiro Abe,Kenji Hiura,Javier Wilde,Keiji Moriyama,Toshihiro Hashimoto,Shuji Ozaki,Shingo Wakatsuki,Masaaki Kosaka,Shinsuke Kido,Daisuke Inoue,Toshio Matsumoto

View Articletitled, Role for macrophage inflammatory protein (MIP)-1α and MIP-1β in the development of osteolytic lesions in multiple myeloma

PHAGOCYTES

Hydrocortisone reduced in vivo, inflammation-induced slow rolling of leukocytes and their extravasation into human conjunctiva

Juha Kirveskari,Maaret Helintö,Jukka A. O. Moilanen,Timo Paavonen,Timo M. T. Tervo,Risto Renkonen

View Articletitled, Hydrocortisone reduced in vivo, inflammation-induced slow rolling of leukocytes and their extravasation into human conjunctiva

RED CELLS

Splenectomy prolongs in vivo survival of erythrocytes differently in spectrin/ankyrin- and band 3–deficient hereditary spherocytosis

Ramune Reliene,Mariagabriella Mariani,Alberto Zanella,Walter H. Reinhart,M. Leticia Ribeiro,Emanuele Miraglia del Giudice,Silverio Perrotta,Achille Iolascon,Stefan Eber,Hans U. Lutz

View Articletitled, Splenectomy prolongs in vivo survival of erythrocytes differently in spectrin/ankyrin- and band 3–deficient hereditary spherocytosis

TRANSPLANTATION

Aberrant regulation of superantigen responses during T-cell reconstitution and graft-versus-host disease in immunodeficient mice

David Spaner,Xiaofang Sheng-Tanner,Andre C. Schuh

View Articletitled, Aberrant regulation of superantigen responses during T-cell reconstitution and graft-versus-host disease in immunodeficient mice

High-level allogeneic chimerism achieved by prenatal tolerance induction and postnatal nonmyeloablative bone marrow transplantation

William H. Peranteau,Satoshi Hayashi,Michael Hsieh,Aimen F. Shaaban,Alan W. Flake

View Articletitled, High-level allogeneic chimerism achieved by prenatal tolerance induction and postnatal nonmyeloablative bone marrow transplantation

Direct evidence for new T-cell generation by patients after either T-cell–depleted or unmodified allogeneic hematopoietic stem cell transplantations: Presented in part in abstract form at the 42nd Annual Meeting of the American Society of Hematology, San Francisco, CA, December 2000.

Sharon R. Lewin,Glenn Heller,Linqi Zhang,Elaine Rodrigues,Eva Skulsky,Marcel R. M. van den Brink,Trudy N. Small,Nancy A. Kernan,Richard J. O'Reilly,David D. Ho,James W. Young

View Articletitled, Direct evidence for new T-cell generation by patients after either T-cell–depleted or unmodified allogeneic hematopoietic stem cell transplantations: Presented in part in abstract form at the 42nd Annual Meeting of the American Society of Hematology, San Francisco, CA, December 2000.

BRIEF REPORTS

Evidence for a graft-versus-leukemia effect after allogeneic peripheral blood stem cell transplantation with reduced-intensity conditioning in acute myelogenous leukemia and myelodysplastic syndromes
Clinical Trials & Observations Brief Report

Rodrigo Martino,Marı́a Dolores Caballero,José Antonio Pérez Simón,Carmen Canals,Carlos Solano,Alvaro Urbano-Ispı́zua,Joan Bargay,Angel Léon,Josep Sarrá,Guillermo F. Sanz,José Marı́a Moraleda,Salut Brunet,Jesús San Miguel,Jorge Sierra,for the AML and alloPBSCT subcommittees of the Spanish Group for Hematopoietic Transplantation (GETH)

View Articletitled, Evidence for a graft-versus-leukemia effect after allogeneic peripheral blood stem cell transplantation with reduced-intensity conditioning in acute myelogenous leukemia and myelodysplastic syndromes

Anemia and iron overload due to compound heterozygosity for novel ceruloplasmin mutations
Brief Report

Sandra Bosio,Marco De Gobbi,Antonella Roetto,Gabriella Zecchina,Eugenio Leonardo,Mario Rizzetto,Claudio Lucetti,Lucia Petrozzi,Ubaldo Bonuccelli,Clara Camaschella

View Articletitled, Anemia and iron overload due to compound heterozygosity for novel ceruloplasmin mutations

Prolongation of cardiac repolarization by arsenic trioxide
Clinical Trials & Observations Brief Report

Chern-En Chiang,Hsiang-Ning Luk,Tsui-Ming Wang,Philip Yu-An Ding

View Articletitled, Prolongation of cardiac repolarization by arsenic trioxide

DNB: a partial D with anti-D frequent in Central Europe
Brief Report

Franz F. Wagner,Nicole I. Eicher,Jan R. Jørgensen,Cornelie B. Lonicer,Willy A. Flegel

View Articletitled, DNB: a partial D with anti-D frequent in Central Europe

Rituximab treatment results in impaired secondary humoral immune responsiveness
Clinical Trials & Observations Brief Report

Lizet E. van der Kolk,Joke W. Baars,Martin H. Prins,Marinus H. J. van Oers

View Articletitled, Rituximab treatment results in impaired secondary humoral immune responsiveness

Rituximab treatment of refractory fludarabine-associated immune thrombocytopenia in chronic lymphocytic leukemia
Clinical Trials & Observations Brief Report

Upendra P. Hegde,Wyndham H. Wilson,Therese White,Bruce D. Cheson

View Articletitled, Rituximab treatment of refractory fludarabine-associated immune thrombocytopenia in chronic lymphocytic leukemia

Polymorphisms of the tumor necrosis factor-α gene promoter predict for outcome after thalidomide therapy in relapsed and refractory multiple myeloma
Clinical Trials & Observations Brief Report

Kai Neben,Joannis Mytilineos,Thomas M. Moehler,Astrid Preiss,Alwin Kraemer,Anthony D. Ho,Gerhard Opelz,Hartmut Goldschmidt

View Articletitled, Polymorphisms of the tumor necrosis factor-α gene promoter predict for outcome after thalidomide therapy in relapsed and refractory multiple myeloma

CORRESPONDENCE

Adult onset and atypical presentation of hemophagocytic lymphohistiocytosis in siblings carryingPRF1 mutations

Rita Clementi,Lorenzo Emmi,Rita Maccario,Francesco Liotta,Lorenzo Moretta,Cesare Danesino,Maurizio Aricò

View Articletitled, Adult onset and atypical presentation of hemophagocytic lymphohistiocytosis in siblings carryingPRF1 mutations

Transcription of AML1/ETO in bone marrow and cord blood of individuals without acute myelogenous leukemia

Jorg Basecke,Lukas Cepek,Christine Mannhalter,Jurgen Krauter,Stefanie Hildenhagen,Guenter Brittinger,Lorenz Trumper,Frank Griesinger

View Articletitled, Transcription of AML1/ETO in bone marrow and cord blood of individuals without acute myelogenous leukemia

Tumor necrosis factor α promoter polymorphisms and liver abnormalities of homozygotes for the 845G>A (C282Y) hereditary hemochromatosis mutation

Ernest Beutler,Terri Gelbart

View Articletitled, Tumor necrosis factor α promoter polymorphisms and liver abnormalities of homozygotes for the 845G>A (C282Y) hereditary hemochromatosis mutation

Glycosylation of V region genes in follicular lymphoma as a result of the somatic hypermutation mechanism

Chrysoula Belessi,Kostas Stamatopoulos,Christos Kosmas

View Articletitled, Glycosylation of V region genes in follicular lymphoma as a result of the somatic hypermutation mechanism

TT virus does not contaminate first-generation recombinant factor VIII concentrate

Thomas R. Kreil,Klaus Zimmermann,Sabrina Pable,Hans Peter Schwarz,Friedrich Dorner

View Articletitled, TT virus does not contaminate first-generation recombinant factor VIII concentrate

Deep-vein thrombosis in patients with multiple myeloma receiving first-line thalidomide-dexamethasone therapy

Michele Cavo,Elena Zamagni,Claudia Cellini,Patrizia Tosi,Delia Cangini,Michela Cini,Lelia Valdrè,Gualtiero Palareti,Luciano Masini,Sante Tura,Michele Baccarani

View Articletitled, Deep-vein thrombosis in patients with multiple myeloma receiving first-line thalidomide-dexamethasone therapy

Involvement of the MLL gene in T-lineage acute lymphoblastic leukemia

Anthony V. Moorman,Sue Richards,Christine J. Harrison

View Articletitled, Involvement of the MLL gene in T-lineage acute lymphoblastic leukemia

Megakaryocytes from chronic myeloproliferative disorders show enhanced nuclear bFGF expression

Oliver Bock,Jerome Schlué,Ulrich Lehmann,Reinhard von Wasielewski,Florian Länger,Hans Kreipe

View Articletitled, Megakaryocytes from chronic myeloproliferative disorders show enhanced nuclear bFGF expression

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Determining Treatment Tolerance and Fitness for Intensive Chemotherapy in Older Adults with AML: A Call to Action

Dual-receptor T cell platform with Ab-TCR and costimulatory receptor achieves specificity and potency against AML

TRANSCRIPTIONAL CONTROL OF LEUKEMOGENESIS BY THE CHROMATIN READER SGF29

CSF1R inhibition promotes neuroinflammation and behavioural deficits during graft-versus-host disease in mice

Impaired O₂ unloading from stored blood results in diffusion-limited O₂ release at tissues: evidence from human kidneys

Issue Archive

Table of Contents

INSIDE BLOOD

REVIEW ARTICLES

CHEMOKINES

CLINICAL OBSERVATIONS, INTERVENTIONS, AND THERAPEUTIC TRIALS

Racial and ethnic differences in survival of children with acute lymphoblastic leukemia Clinical Trials & Observations

A phase 2 study of imatinib in patients with relapsed or refractory Philadelphia chromosome–positive acute lymphoid leukemias Clinical Trials & Observations

Clinicobiological features and outcome of acute promyelocytic leukemia occurring as a second tumor: the GIMEMA experience Clinical Trials & Observations

Ursodeoxycholic acid for the prevention of hepatic complications in allogeneic stem cell transplantation Clinical Trials & Observations

Stanford V regimen and concomitant HAART in 59 patients with Hodgkin disease and HIV infection Clinical Trials & Observations

Second malignancy after Hodgkin disease treated with radiation therapy with or without chemotherapy: long-term risks and risk factors Clinical Trials & Observations

Bone marrow transplantation from HLA-identical siblings as treatment for myelodysplasia Clinical Trials & Observations

High incidence of human herpesvirus 6 infection with a high viral load in cord blood stem cell transplant recipients Clinical Trials & Observations

GENE THERAPY

HEMATOPOIESIS

HEMOSTASIS, THROMBOSIS, AND VASCULAR BIOLOGY

A common polymorphism in the annexin V Kozak sequence (−1C>T) increases translation efficiency and plasma levels of annexin V, and decreases the risk of myocardial infarction in young patients Clinical Trials & Observations

IMMUNOBIOLOGY

A prospective study on the evolution of the T-cell repertoire in patients with Sézary syndrome treated by extracorporeal photopheresis Clinical Trials & Observations

NEOPLASIA

PHAGOCYTES

RED CELLS

TRANSPLANTATION

BRIEF REPORTS

Evidence for a graft-versus-leukemia effect after allogeneic peripheral blood stem cell transplantation with reduced-intensity conditioning in acute myelogenous leukemia and myelodysplastic syndromes Clinical Trials & Observations Brief Report

Anemia and iron overload due to compound heterozygosity for novel ceruloplasmin mutations Brief Report

Prolongation of cardiac repolarization by arsenic trioxide Clinical Trials & Observations Brief Report

DNB: a partial D with anti-D frequent in Central Europe Brief Report

Rituximab treatment results in impaired secondary humoral immune responsiveness Clinical Trials & Observations Brief Report

Rituximab treatment of refractory fludarabine-associated immune thrombocytopenia in chronic lymphocytic leukemia Clinical Trials & Observations Brief Report

Polymorphisms of the tumor necrosis factor-α gene promoter predict for outcome after thalidomide therapy in relapsed and refractory multiple myeloma Clinical Trials & Observations Brief Report

CORRESPONDENCE

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American Society of Hematology

This Feature Is Available To Subscribers Only

Racial and ethnic differences in survival of children with acute lymphoblastic leukemia
Clinical Trials & Observations

A phase 2 study of imatinib in patients with relapsed or refractory Philadelphia chromosome–positive acute lymphoid leukemias
Clinical Trials & Observations

Clinicobiological features and outcome of acute promyelocytic leukemia occurring as a second tumor: the GIMEMA experience
Clinical Trials & Observations

Ursodeoxycholic acid for the prevention of hepatic complications in allogeneic stem cell transplantation
Clinical Trials & Observations

Stanford V regimen and concomitant HAART in 59 patients with Hodgkin disease and HIV infection
Clinical Trials & Observations

Second malignancy after Hodgkin disease treated with radiation therapy with or without chemotherapy: long-term risks and risk factors
Clinical Trials & Observations

Bone marrow transplantation from HLA-identical siblings as treatment for myelodysplasia
Clinical Trials & Observations

High incidence of human herpesvirus 6 infection with a high viral load in cord blood stem cell transplant recipients
Clinical Trials & Observations

A common polymorphism in the annexin V Kozak sequence (−1C>T) increases translation efficiency and plasma levels of annexin V, and decreases the risk of myocardial infarction in young patients
Clinical Trials & Observations

A prospective study on the evolution of the T-cell repertoire in patients with Sézary syndrome treated by extracorporeal photopheresis
Clinical Trials & Observations

Evidence for a graft-versus-leukemia effect after allogeneic peripheral blood stem cell transplantation with reduced-intensity conditioning in acute myelogenous leukemia and myelodysplastic syndromes
Clinical Trials & Observations Brief Report

Anemia and iron overload due to compound heterozygosity for novel ceruloplasmin mutations
Brief Report

Prolongation of cardiac repolarization by arsenic trioxide
Clinical Trials & Observations Brief Report

DNB: a partial D with anti-D frequent in Central Europe
Brief Report

Rituximab treatment results in impaired secondary humoral immune responsiveness
Clinical Trials & Observations Brief Report

Rituximab treatment of refractory fludarabine-associated immune thrombocytopenia in chronic lymphocytic leukemia
Clinical Trials & Observations Brief Report

Polymorphisms of the tumor necrosis factor-α gene promoter predict for outcome after thalidomide therapy in relapsed and refractory multiple myeloma
Clinical Trials & Observations Brief Report