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INSIDE BLOOD

G-CSF and monosomy 7 in marrow failure patients

Neal S. Young

View Articletitled, G-CSF and monosomy 7 in marrow failure patients

PNH cells are hard to kill

Lucio Luzzatto

View Articletitled, PNH cells are hard to kill

Recurrent venous thromboembolism and pregnancy

Barbara Alving

View Articletitled, Recurrent venous thromboembolism and pregnancy

Factor V Leiden and the genetics of myocardial infarction: we need to look elsewhere

Björn Dahlbäck

View Articletitled, Factor V Leiden and the genetics of myocardial infarction: we need to look elsewhere

REVIEW ARTICLES

Role of factor XIII in fibrin clot formation and effects of genetic polymorphisms

Robert A. S. Ariëns,Thung-Shenq Lai,John W. Weisel,Charles S. Greenberg,Peter J. Grant

View Articletitled, Role of factor XIII in fibrin clot formation and effects of genetic polymorphisms

CLINICAL OBSERVATIONS, INTERVENTIONS, AND THERAPEUTIC TRIALS

Autologous stem cell transplantation followed by a dose-reduced allograft induces high complete remission rate in multiple myeloma
Clinical Trials & Observations

Nicolaus Kröger,Rainer Schwerdtfeger,Michael Kiehl,Herbert Gottfried Sayer,Helmut Renges,Tatjana Zabelina,Boris Fehse,Florian Tögel,Georg Wittkowsky,Rolf Kuse,Axel Rolf Zander

View Articletitled, Autologous stem cell transplantation followed by a dose-reduced allograft induces high complete remission rate in multiple myeloma

Transplantation of mobilized peripheral blood cells to HLA-identical siblings with standard-risk leukemia
Clinical Trials & Observations

Norbert Schmitz,Meral Beksac,Dirk Hasenclever,Andrea Bacigalupo,Tapani Ruutu,Arnon Nagler,Eliane Gluckman,Nigel Russell,Jane F. Apperley,Norbert C. Gorin,Jeff Szer,Ken Bradstock,Agnes Buzyn,Peter Clark,Keith Borkett,Alois Gratwohl,for the European Group for Blood and Marrow Transplantation

View Articletitled, Transplantation of mobilized peripheral blood cells to HLA-identical siblings with standard-risk leukemia

Phase II trial of subcutaneous anti-CD52 monoclonal antibody alemtuzumab (Campath-1H) as first-line treatment for patients with B-cell chronic lymphocytic leukemia (B-CLL)
Clinical Trials & Observations

Jeanette Lundin,Eva Kimby,Magnus Björkholm,Per-Anders Broliden,Fredrik Celsing,Viktoria Hjalmar,Lars Möllgård,Peppy Rebello,Geoff Hale,Herman Waldmann,Håkan Mellstedt,Anders Österborg

View Articletitled, Phase II trial of subcutaneous anti-CD52 monoclonal antibody alemtuzumab (Campath-1H) as first-line treatment for patients with B-cell chronic lymphocytic leukemia (B-CLL)

Allogeneic bone marrow transplantation: cure for familial Mediterranean fever
Clinical Trials & Observations

John Milledge,Peter J. Shaw,Albert Mansour,Sarah Williamson,Bruce Bennetts,Tony Roscioli,Julie Curtin,John Christodoulou

View Articletitled, Allogeneic bone marrow transplantation: cure for familial Mediterranean fever

von Willebrand factor cleaving protease (ADAMTS13) is deficient in recurrent and familial thrombotic thrombocytopenic purpura and hemolytic uremic syndrome
Clinical Trials & Observations

Giuseppe Remuzzi,Miriam Galbusera,Marina Noris,Maria Teresa Canciani,Erica Daina,Elena Bresin,Silvia Contaretti,Jessica Caprioli,Sara Gamba,Piero Ruggenenti,Norberto Perico,Pier Mannuccio Mannucci,for the Italian Registry of Recurrent and Familial HUS/TTP

View Articletitled, von Willebrand factor cleaving protease (ADAMTS13) is deficient in recurrent and familial thrombotic thrombocytopenic purpura and hemolytic uremic syndrome

Risk factors for evolution of acquired aplastic anemia into myelodysplastic syndrome and acute myeloid leukemia after immunosuppressive therapy in children
Clinical Trials & Observations

Seiji Kojima,Akira Ohara,Masahiro Tsuchida,Toru Kudoh,Ryoji Hanada,Yuri Okimoto,Takashi Kaneko,Toshikuni Takano,Koichiro Ikuta,Ichiro Tsukimoto,for the Japan Childhood Aplastic Anemia Study Group

View Articletitled, Risk factors for evolution of acquired aplastic anemia into myelodysplastic syndrome and acute myeloid leukemia after immunosuppressive therapy in children

Myelodysplastic syndrome is not merely “preleukemia”
Clinical Trials & Observations

Maher Albitar,Taghi Manshouri,Yu Shen,Diane Liu,Miloslav Beran,Hagop M. Kantarjian,Anna Rogers,Iman Jilani,Chung Wu Lin,Sherry Pierce,Emil J. Freireich,Elihu H. Estey

View Articletitled, Myelodysplastic syndrome is not merely “preleukemia”

Outcome of 154 patients with severe aplastic anemia who received transplants from unrelated donors: the Japan Marrow Donor Program
Clinical Trials & Observations

Seiji Kojima,Takaharu Matsuyama,Shunichi Kato,Hisato Kigasawa,Ryoji Kobayashi,Atsushi Kikuta,Hisashi Sakamaki,Koichiro Ikuta,Masahiro Tsuchida,Yasutaka Hoshi,Yasuo Morishima,Yoshihisa Kodera

View Articletitled, Outcome of 154 patients with severe aplastic anemia who received transplants from unrelated donors: the Japan Marrow Donor Program

Complete allogeneic hematopoietic chimerism achieved by a combined strategy of in utero hematopoietic stem cell transplantation and postnatal donor lymphocyte infusion
Clinical Trials & Observations

Satoshi Hayashi,William H. Peranteau,Aimen F. Shaaban,Alan W. Flake

View Articletitled, Complete allogeneic hematopoietic chimerism achieved by a combined strategy of in utero hematopoietic stem cell transplantation and postnatal donor lymphocyte infusion

GENE THERAPY

Lentiviral vectors containing the human immunodeficiency virus type-1 central polypurine tract can efficiently transduce nondividing hepatocytes and antigen-presenting cells in vivo

Thierry VandenDriessche,Lieven Thorrez,Luigi Naldini,Antonia Follenzi,Lieve Moons,Zwi Berneman,Desire Collen,Marinee K. L. Chuah

View Articletitled, Lentiviral vectors containing the human immunodeficiency virus type-1 central polypurine tract can efficiently transduce nondividing hepatocytes and antigen-presenting cells in vivo

Lentiviral vectors pseudotyped with a modified RD114 envelope glycoprotein show increased stability in sera and augmented transduction of primary lymphocytes and CD34⁺ cells derived from human and nonhuman primates

Virginie Sandrin,Bertrand Boson,Patrick Salmon,Wilfried Gay,Didier Nègre,Roger Le Grand,Didier Trono,François-Loı̈c Cosset

View Articletitled, Lentiviral vectors pseudotyped with a modified RD114 envelope glycoprotein show increased stability in sera and augmented transduction of primary lymphocytes and CD34+ cells derived from human and nonhuman primates

HEMATOPOIESIS

Development of a murine hematopoietic progenitor complementary DNA microarray using a subtracted complementary DNA library

Xianyong Ma,Tupur Husain,Hui Peng,Sharon Lin,Olga Mironenko,Noel Maun,Steven Johnson,David Tuck,Nancy Berliner,Diane S. Krause,Archibald S. Perkins

View Articletitled, Development of a murine hematopoietic progenitor complementary DNA microarray using a subtracted complementary DNA library

Down-regulation of DNA repair in human CD34⁺progenitor cells corresponds to increased drug sensitivity and apoptotic response

Claudia Buschfort-Papewalis,Thomas Moritz,Bernd Liedert,Jürgen Thomale

View Articletitled, Down-regulation of DNA repair in human CD34+progenitor cells corresponds to increased drug sensitivity and apoptotic response

Evaluation of role of G-CSF in the production, survival, and release of neutrophils from bone marrow into circulation

Sunanda Basu,George Hodgson,Melissa Katz,Ashley R. Dunn

View Articletitled, Evaluation of role of G-CSF in the production, survival, and release of neutrophils from bone marrow into circulation

Deregulated expression of HOXB4 enhances the primitive growth activity of human hematopoietic cells

Christian Buske,Michaela Feuring-Buske,Carolina Abramovich,Karsten Spiekermann,Connie J. Eaves,Laure Coulombel,Guy Sauvageau,Donna E. Hogge,R. Keith Humphries

View Articletitled, Deregulated expression of HOXB4 enhances the primitive growth activity of human hematopoietic cells

Functional analysis of human hematopoietic repopulating cells mobilized with granulocyte colony-stimulating factor alone versus granulocyte colony-stimulating factor in combination with stem cell factor

David A. Hess,Krysta D. Levac,Francis N. Karanu,Michael Rosu-Myles,Martin J. White,Lisa Gallacher,Barbara Murdoch,Michael Keeney,Pamela Ottowski,Ronan Foley,Ian Chin-Yee,Mickie Bhatia

View Articletitled, Functional analysis of human hematopoietic repopulating cells mobilized with granulocyte colony-stimulating factor alone versus granulocyte colony-stimulating factor in combination with stem cell factor

HEMOSTASIS, THROMBOSIS, AND VASCULAR BIOLOGY

Pro-oxidant and cytotoxic effects of circulating heme

Viktória Jeney,József Balla,Akihiro Yachie,Zsuzsa Varga,Gregory M. Vercellotti,John W. Eaton,György Balla

View Articletitled, Pro-oxidant and cytotoxic effects of circulating heme

Characterization of Kaposi sarcoma–associated herpesvirus/human herpesvirus–8 infection of human vascular endothelial cells: early events

Bruce J. Dezube,Maria Zambela,David R. Sage,Jian-Feng Wang,Joyce D. Fingeroth

View Articletitled, Characterization of Kaposi sarcoma–associated herpesvirus/human herpesvirus–8 infection of human vascular endothelial cells: early events

Stomatin is a major lipid-raft component of platelet α granules

Mario Mairhofer,Marianne Steiner,Wilhelm Mosgoeller,Rainer Prohaska,Ulrich Salzer

View Articletitled, Stomatin is a major lipid-raft component of platelet α granules

A monoclonal antibody to vascular endothelial–cadherin inhibits tumor angiogenesis without side effects on endothelial permeability

Monica Corada,Lucia Zanetta,Fabrizio Orsenigo,Ferruccio Breviario,Maria Grazia Lampugnani,Sergio Bernasconi,Fang Liao,Daniel J. Hicklin,Peter Bohlen,Elisabetta Dejana

View Articletitled, A monoclonal antibody to vascular endothelial–cadherin inhibits tumor angiogenesis without side effects on endothelial permeability

c-myc proto-oncogene expression in hemophilic synovitis: in vitro studies of the effects of iron and ceramide

Fei-Qiu Wen,Adnan A. Jabbar,Yi-Xin Chen,Tamara Kazarian,Dharmesh A. Patel,Leonard A. Valentino

View Articletitled, c-myc proto-oncogene expression in hemophilic synovitis: in vitro studies of the effects of iron and ceramide

NAD(P)H oxidase–dependent platelet superoxide anion release increases platelet recruitment

Florian Krötz,Hae Young Sohn,Torsten Gloe,Stefan Zahler,Tobias Riexinger,Thomas M. Schiele,Bernhard F. Becker,Karl Theisen,Volker Klauss,Ulrich Pohl

View Articletitled, NAD(P)H oxidase–dependent platelet superoxide anion release increases platelet recruitment

IMMUNOBIOLOGY

Nucleotides induce chemotaxis and actin polymerization in immature but not mature human dendritic cells via activation of pertussis toxin–sensitive P2y receptors

Marco Idzko,Stefan Dichmann,Davide Ferrari,Francesco Di Virgilio,Andrea la Sala,Giampiero Girolomoni,Elisabeth Panther,Johannes Norgauer

View Articletitled, Nucleotides induce chemotaxis and actin polymerization in immature but not mature human dendritic cells via activation of pertussis toxin–sensitive P2y receptors

Epstein-Barr virus–specific CD8⁺ T cells that re-express CD45RA are apoptosis-resistant memory cells that retain replicative potential

Padraic J. Dunne,Jeffery M. Faint,Nancy H. Gudgeon,Jean M. Fletcher,Fiona J. Plunkett,Maria Vieira D. Soares,Andrew D. Hislop,Nicola E. Annels,Alan B. Rickinson,Mike Salmon,Arne N. Akbar

View Articletitled, Epstein-Barr virus–specific CD8+ T cells that re-express CD45RA are apoptosis-resistant memory cells that retain replicative potential

Immunologic mechanisms of extracorporeal photochemotherapy in chronic graft-versus-host disease
Clinical Trials & Observations

Gullu Gorgun,Kenneth B. Miller,Francine M. Foss

View Articletitled, Immunologic mechanisms of extracorporeal photochemotherapy in chronic graft-versus-host disease

Analysis of Vλ-Jλ expression in plasma cells from primary (AL) amyloidosis and normal bone marrow identifies 3r(λIII) as a new amyloid-associated germline gene segment

Vittorio Perfetti,Simona Casarini,Giovanni Palladini,Maurizio Colli Vignarelli,Catherine Klersy,Marta Diegoli,Edoardo Ascari,Giampaolo Merlini

View Articletitled, Analysis of Vλ-Jλ expression in plasma cells from primary (AL) amyloidosis and normal bone marrow identifies 3r(λIII) as a new amyloid-associated germline gene segment

Hematopoietic progenitor kinase 1 supports apoptosis of T lymphocytes

Jan Schulze-Luehrmann,Brigitte Santner-Nanan,Mithilesh Kumar Jha,Anneliese Schimpl,Andris Avots,Edgar Serfling

View Articletitled, Hematopoietic progenitor kinase 1 supports apoptosis of T lymphocytes

NEOPLASIA

Sperm protein 17 (Sp17) is a suitable target for immunotherapy of multiple myeloma

Maurizio Chiriva-Internati,Zhiqing Wang,Emanuela Salati,Klaus Bumm,Bart Barlogie,Seah H. Lim

View Articletitled, Sperm protein 17 (Sp17) is a suitable target for immunotherapy of multiple myeloma

Functional involvement of Akt signaling downstream of Jak1 in v-Abl–induced activation of hematopoietic cells

Shinji Oki,Andre Limnander,Nika N. Danial,Paul B. Rothman

View Articletitled, Functional involvement of Akt signaling downstream of Jak1 in v-Abl–induced activation of hematopoietic cells

MDR1 protein expression is an independent predictor of complete remission in newly diagnosed adult acute lymphoblastic leukemia

View Articletitled, MDR1 protein expression is an independent predictor of complete remission in newly diagnosed adult acute lymphoblastic leukemia

Regulation of leukemic cell adhesion, proliferation, and survival by β-catenin

Eun Joo Chung,Sang-Gu Hwang,PhuongMai Nguyen,Sunmin Lee,Jung-Sik Kim,Jin Woo Kim,Pierre A. Henkart,Donald P. Bottaro,Lilian Soon,Paolo Bonvini,Su-Jae Lee,Judith E. Karp,Ho Jung Oh,Jeffrey S. Rubin,Jane B. Trepel

View Articletitled, Regulation of leukemic cell adhesion, proliferation, and survival by β-catenin

HOX11L2 expression defines a clinical subtype of pediatric T-ALL associated with poor prognosis
Clinical Trials & Observations

Paola Ballerini,Annick Blaise,Maryvonne Busson-Le Coniat,Xin Ying Su,Jessica Zucman-Rossi,Mircea Adam,Jacqueline van den Akker,Christine Perot,Beatrice Pellegrino,Judith Landman-Parker,Luc Douay,Roland Berger,Olivier A. Bernard

View Articletitled, HOX11L2 expression defines a clinical subtype of pediatric T-ALL associated with poor prognosis

Heterozygous PU.1 mutations are associated with acute myeloid leukemia

Beatrice U. Mueller,Thomas Pabst,Motomi Osato,Norio Asou,Lisa M. Johansen,Mark D. Minden,Gerhard Behre,Wolfgang Hiddemann,Yoshiaki Ito,Daniel G. Tenen

View Articletitled, Heterozygous PU.1 mutations are associated with acute myeloid leukemia

Targeted removal of PML-RARα protein is required prior to inhibition of histone deacetylase for overcoming all-trans retinoic acid differentiation resistance in acute promyelocytic leukemia

Yongkui Jing,Lijuan Xia,Samuel Waxman

View Articletitled, Targeted removal of PML-RARα protein is required prior to inhibition of histone deacetylase for overcoming all-trans retinoic acid differentiation resistance in acute promyelocytic leukemia

Several types of mutations of the Abl gene can be found in chronic myeloid leukemia patients resistant to STI571, and they can pre-exist to the onset of treatment

Catherine Roche-Lestienne,Valerie Soenen-Cornu,Nathalie Grardel-Duflos,Jean-Luc Laı̈,Nathalie Philippe,Thierry Facon,Pierre Fenaux,Claude Preudhomme

View Articletitled, Several types of mutations of the Abl gene can be found in chronic myeloid leukemia patients resistant to STI571, and they can pre-exist to the onset of treatment

Engagement of ILT2/CD85j in Sézary syndrome cells inhibits their CD3/TCR signaling

Maria Nikolova,Philippe Musette,Martine Bagot,Laurence Boumsell,Armand Bensussan

View Articletitled, Engagement of ILT2/CD85j in Sézary syndrome cells inhibits their CD3/TCR signaling

PHAGOCYTES

Deletion of leucine 61 in glucose-6-phosphate dehydrogenase leads to chronic nonspherocytic anemia, granulocyte dysfunction, and increased susceptibility to infections

Robin van Bruggen,José M. Bautista,Theoni Petropoulou,Martin de Boer,Rob van Zwieten,Felı́x Gómez-Gallego,Bernd H. Belohradsky,Nico G. Hartwig,David Stevens,Philip J. Mason,Dirk Roos

View Articletitled, Deletion of leucine 61 in glucose-6-phosphate dehydrogenase leads to chronic nonspherocytic anemia, granulocyte dysfunction, and increased susceptibility to infections

RED CELLS

Decreased susceptibility of leukemic cells with PIG-Amutation to natural killer cells in vitro

Shoichi Nagakura,Sonoko Ishihara,Daniel E. Dunn,Jun-ichi Nishimura,Tatsuya Kawaguchi,Kentaro Horikawa,Michihiro Hidaka,Tadashi Kagimoto,Nozomu Eto,Hiroaki Mitsuya,Taroh Kinoshita,Neal S. Young,Hideki Nakakuma

View Articletitled, Decreased susceptibility of leukemic cells with PIG-Amutation to natural killer cells in vitro

Cell-surface expression of RhD blood group polypeptide is posttranscriptionally regulated by the RhAG glycoprotein

Isabelle Mouro-Chanteloup,Anne Marie D'Ambrosio,Pierre Gane,Caroline Le Van Kim,Virginie Raynal,Didier Dhermy,Jean-Pierre Cartron,Yves Colin

View Articletitled, Cell-surface expression of RhD blood group polypeptide is posttranscriptionally regulated by the RhAG glycoprotein

Plasmodium falciparum cysteine protease falcipain-2 cleaves erythrocyte membrane skeletal proteins at late stages of parasite development: Presented in part in abstract form at the 43rd Annual Meeting of the American Society of Hematology, Orlando, FL, 2001.

Manjit Hanspal,Meenakshi Dua,Yuichi Takakuwa,Athar H. Chishti,Akiko Mizuno

View Articletitled, Plasmodium falciparum cysteine protease falcipain-2 cleaves erythrocyte membrane skeletal proteins at late stages of parasite development: Presented in part in abstract form at the 43rd Annual Meeting of the American Society of Hematology, Orlando, FL, 2001.

TRANSFUSION MEDICINE

γ-Globulins prepared from sera of multiparous women bind anti-HLA antibodies and inhibit an established in vivo human alloimmune response

John W. Semple,Michael Kim,Alan H. Lazarus,John Freedman

View Articletitled, γ-Globulins prepared from sera of multiparous women bind anti-HLA antibodies and inhibit an established in vivo human alloimmune response

BRIEF REPORTS

Temporary increase in the risk for recurrence during pregnancy in women with a history of venous thromboembolism
Clinical Trials & Observations Brief Report

Ingrid Pabinger,Helga Grafenhofer,Paul A. Kyrle,Peter Quehenberger,Christine Mannhalter,Klaus Lechner,Alexandra Kaider

View Articletitled, Temporary increase in the risk for recurrence during pregnancy in women with a history of venous thromboembolism

Short deletion within the blood group Dombrock locus causing a Do_null phenotype
Brief Report

Nicole Lucien,Jean-Louis Celton,Pierre-Yves Le Pennec,Jean-Pierre Cartron,Pascal Bailly

View Articletitled, Short deletion within the blood group Dombrock locus causing a Donull phenotype

Complete remission through blast cell differentiation inPLZF/RARα-positive acute promyelocytic leukemia: in vitro and in vivo studies
Clinical Trials & Observations Brief Report

Maria C. Petti,Francesco Fazi,Massimo Gentile,Daniela Diverio,Paolo De Fabritiis,M. Stefania De Propris,Roberto Fiorini,Maria A. Aloe Spiriti,Fabrizio Padula,Pier Giuseppe Pelicci,Clara Nervi,Francesco Lo Coco

View Articletitled, Complete remission through blast cell differentiation inPLZF/RARα-positive acute promyelocytic leukemia: in vitro and in vivo studies

Overcoming STI571 resistance with the farnesyl transferase inhibitor SCH66336
Brief Report

Russell R. Hoover,Francois-Xavier Mahon,Junia V. Melo,George Q. Daley

View Articletitled, Overcoming STI571 resistance with the farnesyl transferase inhibitor SCH66336

A 2-kb c-mpl promoter fragment is sufficient to direct expression to the megakaryocytic lineage and sites of embryonic hematopoiesis in transgenic mice
Brief Report

Sandra Ziegler,Kurt Bürki,Radek C. Skoda

View Articletitled, A 2-kb c-mpl promoter fragment is sufficient to direct expression to the megakaryocytic lineage and sites of embryonic hematopoiesis in transgenic mice

Transferrin receptor 2 (TfR2) and HFEmutational analysis in non-C282Y iron overload: identification of a novel TfR2 mutation
Clinical Trials & Observations Brief Report

Andre Mattman,David Huntsman,Gillian Lockitch,Sylvie Langlois,Noel Buskard,Diana Ralston,Yaron Butterfield,Pedro Rodrigues,Steven Jones,Graça Porto,Marco Marra,Maria De Sousa,Greg Vatcher

View Articletitled, Transferrin receptor 2 (TfR2) and HFEmutational analysis in non-C282Y iron overload: identification of a novel TfR2 mutation

Distinct functions for signal transducer and activator of transcription 1 and PU.1 in transcriptional activation of Fc γ receptor I promoter
Brief Report

Saara Aittomäki,Jie Yang,Edward W. Scott,M. Celeste Simon,Olli Silvennoinen

View Articletitled, Distinct functions for signal transducer and activator of transcription 1 and PU.1 in transcriptional activation of Fc γ receptor I promoter

Vesicle-associated membrane protein 3 (VAMP-3) and VAMP-8 are present in human platelets and are required for granule secretion
Brief Report

János Polgár,Sul-Hee Chung,Guy L. Reed

View Articletitled, Vesicle-associated membrane protein 3 (VAMP-3) and VAMP-8 are present in human platelets and are required for granule secretion

Rapamycin inhibits macropinocytosis and mannose receptor–mediated endocytosis by bone marrow–derived dendritic cells
Brief Report

Holger Hackstein,Timucin Taner,Alison J. Logar,Angus W. Thomson

View Articletitled, Rapamycin inhibits macropinocytosis and mannose receptor–mediated endocytosis by bone marrow–derived dendritic cells

Activity of STI571 in chronic myelomonocytic leukemia with a platelet-derived growth factor β receptor fusion oncogene
Clinical Trials & Observations Brief Report

Magnus K. Magnusson,Kristin E. Meade,Ryotaro Nakamura,John Barrett,Cynthia E. Dunbar

View Articletitled, Activity of STI571 in chronic myelomonocytic leukemia with a platelet-derived growth factor β receptor fusion oncogene

CORRESPONDENCE

CML with an e1a3 BCR-ABL fusion: rare, benign, and a potential diagnostic pitfall

Haifa-Kathria Al-Ali,Sabine Leiblein,Ines Kovacs,Evelin Hennig,Dietger Niederwieser,Michael W. N. Deininger

View Articletitled, CML with an e1a3 BCR-ABL fusion: rare, benign, and a potential diagnostic pitfall

Gene expression changes in blood after phlebotomy: implications for gene expression profiling

Andreas Pahl,Kay Brune

View Articletitled, Gene expression changes in blood after phlebotomy: implications for gene expression profiling

Mutation analysis of transferrin-receptor 2 in patients with atypical hemochromatosis

Wolf-K. Hofmann,Xiang-Jun Tong,Richard S. Ajioka,James P. Kushner,H. Phillip Koeffler

View Articletitled, Mutation analysis of transferrin-receptor 2 in patients with atypical hemochromatosis

CXCR4 expression is associated with survival in familial chronic lymphocytic leukemia, but CD38 expression is not

Naoko Ishibe,Maher Albitar,Iman B. Jilani,Lynn R. Goldin,Gerald E. Marti,Neil E. Caporaso

View Articletitled, CXCR4 expression is associated with survival in familial chronic lymphocytic leukemia, but CD38 expression is not

Leukoencephalopathy and papovavirus infection after treatment with chemotherapy and anti-CD20 monoclonal antibody

Paola Matteucci,Michele Magni,Massimo Di Nicola,Carmelo Carlo-Stella,Caterina Uberti,Alessandro M. Gianni

View Articletitled, Leukoencephalopathy and papovavirus infection after treatment with chemotherapy and anti-CD20 monoclonal antibody

Acquired resistance to imatinib mesylate: selection for pre-existing mutant cells

Lucio Luzzatto,Junia V. Melo

View Articletitled, Acquired resistance to imatinib mesylate: selection for pre-existing mutant cells

Conversion of CD38 and/or myeloid-associated marker expression status during the course of B-CLL: association with a change to an aggressive clinical course

Chung-Che Chang,Ronald P. Cleveland

View Articletitled, Conversion of CD38 and/or myeloid-associated marker expression status during the course of B-CLL: association with a change to an aggressive clinical course

Pathogenic complexity of gastric B-cell lymphoma

Thomas F. E. Barth,Martin Bentz,Frank Leithäuser,Stephan Stilgenbauer,Reiner Siebert,Magdalena Schlotter,Richard F. Schlenk,Hartmut Döhner,Peter Möller

View Articletitled, Pathogenic complexity of gastric B-cell lymphoma

Do B-cell chronic lymphocytic leukemia patients with Ig V_H3-21 genes constitute a new subset of chronic lymphocytic leukemia?

Friedel Nollet,Barbara Cauwelier,Johan Billiet,Dominik Selleslag,Achiel Van Hoof,Andries Louwagie,Arnold Criel

View Articletitled, Do B-cell chronic lymphocytic leukemia patients with Ig VH3-21 genes constitute a new subset of chronic lymphocytic leukemia?

Activating Ras mutations in patients with plasma-cell disorders: a reappraisal

Stéphane Bezieau,Hervé Avet-Loiseau,Jean-Paul Moisan,Régis Bataille

View Articletitled, Activating Ras mutations in patients with plasma-cell disorders: a reappraisal

Issue Archive

Table of Contents

INSIDE BLOOD

REVIEW ARTICLES

CLINICAL OBSERVATIONS, INTERVENTIONS, AND THERAPEUTIC TRIALS

Autologous stem cell transplantation followed by a dose-reduced allograft induces high complete remission rate in multiple myeloma Clinical Trials & Observations

Transplantation of mobilized peripheral blood cells to HLA-identical siblings with standard-risk leukemia Clinical Trials & Observations

Phase II trial of subcutaneous anti-CD52 monoclonal antibody alemtuzumab (Campath-1H) as first-line treatment for patients with B-cell chronic lymphocytic leukemia (B-CLL) Clinical Trials & Observations

Allogeneic bone marrow transplantation: cure for familial Mediterranean fever Clinical Trials & Observations

von Willebrand factor cleaving protease (ADAMTS13) is deficient in recurrent and familial thrombotic thrombocytopenic purpura and hemolytic uremic syndrome Clinical Trials & Observations

Risk factors for evolution of acquired aplastic anemia into myelodysplastic syndrome and acute myeloid leukemia after immunosuppressive therapy in children Clinical Trials & Observations

Myelodysplastic syndrome is not merely “preleukemia” Clinical Trials & Observations

Outcome of 154 patients with severe aplastic anemia who received transplants from unrelated donors: the Japan Marrow Donor Program Clinical Trials & Observations

Complete allogeneic hematopoietic chimerism achieved by a combined strategy of in utero hematopoietic stem cell transplantation and postnatal donor lymphocyte infusion Clinical Trials & Observations

GENE THERAPY

HEMATOPOIESIS

HEMOSTASIS, THROMBOSIS, AND VASCULAR BIOLOGY

IMMUNOBIOLOGY

Immunologic mechanisms of extracorporeal photochemotherapy in chronic graft-versus-host disease Clinical Trials & Observations

NEOPLASIA

HOX11L2 expression defines a clinical subtype of pediatric T-ALL associated with poor prognosis Clinical Trials & Observations

PHAGOCYTES

RED CELLS

TRANSFUSION MEDICINE

BRIEF REPORTS

Temporary increase in the risk for recurrence during pregnancy in women with a history of venous thromboembolism Clinical Trials & Observations Brief Report

Short deletion within the blood group Dombrock locus causing a Donull phenotype Brief Report

Complete remission through blast cell differentiation inPLZF/RARα-positive acute promyelocytic leukemia: in vitro and in vivo studies Clinical Trials & Observations Brief Report

Overcoming STI571 resistance with the farnesyl transferase inhibitor SCH66336 Brief Report

A 2-kb c-mpl promoter fragment is sufficient to direct expression to the megakaryocytic lineage and sites of embryonic hematopoiesis in transgenic mice Brief Report

Transferrin receptor 2 (TfR2) and HFEmutational analysis in non-C282Y iron overload: identification of a novel TfR2 mutation Clinical Trials & Observations Brief Report

Distinct functions for signal transducer and activator of transcription 1 and PU.1 in transcriptional activation of Fc γ receptor I promoter Brief Report

Vesicle-associated membrane protein 3 (VAMP-3) and VAMP-8 are present in human platelets and are required for granule secretion Brief Report

Rapamycin inhibits macropinocytosis and mannose receptor–mediated endocytosis by bone marrow–derived dendritic cells Brief Report

Activity of STI571 in chronic myelomonocytic leukemia with a platelet-derived growth factor β receptor fusion oncogene Clinical Trials & Observations Brief Report