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Research Article December 11 2024
Single-cell epigenetic and clonal analysis decodes disease progression in pediatric acute myeloid leukemia
Research Article December 10 2024
Inflammation-driven NFκB signaling represses Ferroportin transcription in macrophages via HDAC 1 and 3
Research Article December 10 2024
Progressive chromatin rewiring by ETO2::GLIS2 revealed in a human iPSC model of pediatric leukemia initiation
Fabien Boudia,Marie Baille,Loelia Babin,Zakia Aid,Elie Robert,Julie Riviere,Klaudia Galant,Verónica Alonso-Pérez,Laura Anselmi,Brahim Arkoun,Nassera Abermil,Christophe Marzac,Salvatore Nicola Bertuccio,Alexia Regnault de Premesnil,Cecile K. Lopez,Alexandre Eeckhoutte,Audrey Naimo,Betty Leite,Cyril Catelain,Christophe Metereau,Patrick Gonin,Nathalie Gaspar,Juerg Schwaller,Olivier A Bernard,Hana Raslova,Murielle Gaudry,Antonin Marchais,Hélène Lapillonne,Arnaud Petit,Francoise Pflumio,Marie-Laure Arcangeli,Erika Brunet,Thomas Mercher
Research Article December 9 2024
Acute resistance to BET inhibitors remodels compensatory transcriptional programs via p300 coactivation
Viral Shah,George Giotopoulos,Hikari Osaki,Markus Meyerhöfer,Eshwar Meduri,Aaron Gallego-Crespo,Malte Andreas Behrendt,Maria Saura-Pañella,Aarti Tarkar,Benedict Schubert,Haiyang Yun,Sarah J. Horton,Shuchi Agrawal-Singh, Dr,Patricia S Hähnel,Faisal Basheer,Dave Lugo,Ioanna Eleftheriadou,Olena Barbash,Arindam Dhar,Michael Kühn,Borhane Guezguez,Matthias Theobald,Thomas Kindler,Paolo Gallipoli,Paul Sung-Hao Yeh,Mark A. Dawson,Rab K Prinjha,Brian JP Huntly,Daniel Sasca
Research Article December 9 2024
Tumor burden quantified by Soluble B-Cell Maturation Antigen and Metabolic Tumor Volume determine myeloma CAR-T outcomes
Ciara L Freeman,Jerald Noble,Meghan Menges,Ricardo Villanueva,Justyn Y Nakashima,Nicholas B Figura,R. Petter Tonseth,Dietrich Werner Idiaquez,Lawrence Skelson,Eric C Smith,Julieta Abraham-Miranda,Salvatore Corallo,Gabriel De Avila,Omar Castaneda Puglianini,Hien D Liu,Melissa Alsina,Taiga Nishihori,Kenneth H Shain,Rachid C Baz,Brandon J Blue,Ariel Grajales-Cruz,John M. Koomen,Reginald M Atkins,Doris K Hansen,Ariosto Siqueira Silva,Jongphil Kim,Yoganand Balagurunathan,Frederick L Locke
Research Article December 9 2024
Anti-CD19 antibody cotreatment enhances serial killing activity of anti-CD19 CAR-T/-NK cells and reduces trogocytosis
Research Article December 9 2024
The GATA-3-dependent transcriptome and tumor microenvironment are regulated by eIF4E and XPO1 in T-cell lymphomas
Nermin Kady,Suhaib Abdelrahman,Ahmar Rauf,Alyssa Burgess,Jonathan Weiss,Hirushi Gunasekara,Neal Thomas Ramseier,Ira P Maine,Alejandro Zevallos-Morales,Vanessa Perez-Silos,Ashley Wolfe,Alexandra Hristov,Noah A Brown,Kedar V Inamdar,Maria Sverdlov,Ying Samuel Hu,Carlos Murga-Zamalloa,Chenguang Wang,Ryan A Wilcox
Research Article December 9 2024
Efficacy and Safety of Venetoclax Plus Azacitidine for Patients With Treatment-Naive High-Risk Myelodysplastic Syndromes
Research Article December 9 2024
Efficacy and Safety of Daratumumab in Intermediate/High-risk Smoldering Multiple Myeloma: Final Analysis of CENTAURUS
Carl Ola Landgren,Ajai Chari,Yael C. Cohen,Andrew Spencer,Peter M Voorhees,Irwindeep Sandhu,Matthew W Jenner,Dean Smith,Michele Cavo,Niels W.C.J. van de Donk,Meral Beksac,Phillippe Moreau,Hartmut Goldschmidt,Diego Vieyra,Linlin Sha,Liang Li,Els Rousseau,Robyn M. Dennis,Robin Carson,Craig C. Hofmeister
Research Article December 6 2024
A New Severe Congenital Neutropenia Syndrome Associated with Autosomal Recessive COPZ1 Mutations
Natalia Borbaran Bravo,Ekaterina Deordieva,Larissa Doll,Mohammad ElGamacy,Benjamin Dannenmann,Joana Azevedo,Alberto Iannuzzo,Selket Delafontaine,Moritz Lehners,Marius Sebastian Theo Kolodziej,Birte Hernandez Alvarez,Anna-Sophia Hellmuth,Malte Ritter,Betül Findik,Viktoria Zakharova,Sandro Bräuning,Sergey Kandabarau,Claudia Lengerke,Robert Feil,Isabelle Meyts,Jérôme Delon,Markus F. Templin,Marc Sturm,Olaf Rieß,Cornelia Zeidler,Karl Welte,Anna Shcherbina,Maksim Klimiankou,Julia Skokowa
Review Article December 4 2024
Honing CAR T cells to tackle acute myeloid leukemia
Research Article December 4 2024
BRAFV600E induces key features of LCH in iPSCs with cell type-specific phenotypes and drug responses
Research Article December 4 2024
Targeted interferon therapy with modakafusp alfa for relapsed or refractory multiple myeloma
Review Article November 22 2024
The Contribution of the Monocyte‐Macrophage Lineage to Immunotherapy Outcomes
Letter November 22 2024
Beyond static measurements: dynamic frailty improves survival prediction in multiple myeloma
F. Smits,Kaz Groen,Mark-David Levin,Claudia Stege,Roel J.W. van Kampen,Ellen van der Spek,Yavuz M. Bilgin,Noortje Thielen,Inger S. Nijhof,Inge Ludwig,Esther G.M. de Waal,Yorick Sandberg,Alain Kentos,Gert-Jan Timmers,Josien C. Regelink,Matthijs Westerman,Koen de Heer,Marie-Christiane MB Vekemans,Nazik Durdu-Rayman,Nicole C.H.P. de Graauw,Maarten R. Seefat,Niels W.C.J. van de Donk,Paula F Ypma,Kazem Nasserinejad,Sonja Zweegman
Research Article November 22 2024
Itacitinib for Prevention of Graft-Versus-Host Disease and Cytokine Release Syndrome in Haploidentical Transplantation
Research Article November 22 2024
Prothrombotic Antibodies Targeting the Spike Protein's Receptor-Binding Domain in Severe COVID-19
Wen Zhu,Yongwei Zheng,Mei Yu,Nathan Witman,Lu Zhou,Jianhui Wei,Yongguang Zhang,Paytsar Topchyan,Christine Nguyen,Rae Janecke,Anand Padmanabhan,Lisa Baumann Kreuziger,Gilbert C White,Parameswaran Hari,Tongjun Gu,Alexander Thompson Fields,Lucy Kornblith,Richard H Aster,Jieqing Zhu,Weiguo Cui,Shawn M Jobe,Mary Beth Graham,Demin Wang,David Wang,Renren Wen
Research Article November 21 2024
CD70 CAR T cells secreting an anti-CD33/anti-CD3 dual targeting antibody overcome antigen heterogeneity in AML
Research Article November 21 2024
Serum free light chains in a racially diverse population including African Americans and populations from South Africa
Luca Bertamini,Jean-Baptiste Alberge,David Jungpa Lee,Habib El-Khoury,Sungjae Kim,Grace Fleming,Ciara Suen Marie Murphy,Julia Colchie,Maya I Davis,Jacqueline Perry,Elizabeth D Lightbody,Sabine Allam,Lindokuhle N Goqwana,Vinitha Philip,Natalie Anne Smyth, NA,Dhananjay Sakrikar,Mark C Perkins,Stephen Harding,Derek Troske,Gad Getz,Elizabeth W Karlson,Nikhil C. Munshi,Kenneth C. Anderson,Lorenzo Trippa,Catherine R Marinac,Wenlong Carl Chen,Maureen Joffe,Irene M Ghobrial
Letter November 21 2024
Inflammatory Waldenström Macroglobulinemia is associated with clonal hematopoiesis: a multicentric cohort
Pierre-Edouard Debureaux,Stéphanie Poulain,Stephanie Harel,Marie Passet,Marie Templé,Chloe Friedrich,Nathalie Forgeard,Dikelele Elessa,William Plas,Laureen Chat,Gregory Lazarian,Lise Willems,Bruno Royer,Alexis Talbot,Tristan Vaugeois, Dr.,Floriane Theves,Alexandre Terré,Anne C. Brignier,Marion Malphettes,Daphné Krzisch,Laurent Frenzel,Frédéric Davi,Clotilde Bravetti,Florence Nguyen-Khac,Jehan Dupuis,Wendy Cuccuini,Didier Bouscary,Olivier Hermine,Damien Roos-Weil,Olivier Kosmider,Emmanuelle Clappier,Marion Espéli,Karl Balabanian,Bertrand Arnulf
Research Article November 19 2024
Bivalent CD47 Immunotoxin for Targeted Therapy of T-Cell Acute Lymphoblastic Leukemia
Research Article November 19 2024
Development of ALL-Hematotox (ALL-HT): Predicting post CAR T-cell hematotoxicity in B-cell acute lymphoblastic leukemia
Research Article November 19 2024
Preclinical efficacy of CDK7 inhibitor-based combinations against myeloproliferative neoplasms transformed to AML
Warren Fiskus,Christopher P Mill,Prithviraj Bose,Lucia Masarova,Naveen Pemmaraju,Andrew Dunbar,Christine Birdwell,John A Davis,Kaberi Das,Hanxi Hou,Taghi Manshouri,Antrix Jain,Anna Malovannaya,Kevin Philip,Noor Alhamadani,Alicia Matthews,Katie Lin,Lauren Flores,Sanam Loghavi,Courtney D. DiNardo,Xiaoping Su,Raajit K. Rampal,Kapil N Bhalla
Review Article November 14 2024
Approaching a therapeutic inflection point for FLT3-mutated AML
Review Article November 14 2024
Imetelstat: A new addition to the Therapeutic Landscape of Lower-Risk MDS
Research Article November 14 2024
Ferroptosis regulates hemolysis in stored murine and human red blood cells
Angelo D'Alessandro,Gregory R Keele,Ariel M Hay,Travis Nemkov,Eric J Earley,Daniel Stephenson,Matthew Vincent,Xutao Deng,Mars Stone,Monika Dzieciatkowska,Kirk C Hansen,Steven H Kleinman,Steven L Spitalnik,Nareg H Roubinian,Philip J Norris,Michael P Busch,Grier P Page,Brent Stockwell,Gary A Churchill,James C Zimring
Research Article November 1 2024
Safety and efficacy of pegcetacoplan treatment for cold agglutinin disease and warm antibody autoimmune hemolytic anemia
Research Article November 1 2024
Childhood Langerhans cell histiocytosis hematological involvement: severity associated with BRAFV600E loads
Julian Thalhammer,Eric Jeziorski,Perrrine Marec-Berard,Mohamed-Aziz Barkaoui,Anne Pagnier,Pierre-Simon Rohrlich,Aurore Chevallier,Liana Carausu,Nathalie Aladjidi,Charlotte Rigaud,Amaury Leruste,Saba Azarnoush,Thomas Lauvray,Solenne Le Louet,Virginie Gandemer,Pauline Treguier,Ludovic Mansuy,Marlène Pasquet,Laura Olivier,Angélique Rome,Paul Saultier,Florentina Isfan,Cecile Renard,Valérie Li Thiao Te,Alexandra Salmon,Laurence Blanc,Wadih Abou Chahla,Anne Lambilliotte,Jean-Louis Louis Stephan,Frederic Geissmann,Julien Lejeune,Coralie Mallebranche,Yves Reguerre,Audrey Grain,Caroline Thomas,Zofia Hélias-Rodzewicz,Despina Moshous,Odile Fenneteau,Aurore Coulomb-L'hermine,Hélène Lapillonne,Geneviève de Saint Basile,Jean-Francois Emile,Sébastien Héritier,Jean Donadieu
Review Article November 1 2024
Long-term Outcomes of tyrosine kinase inhibitors in chronic myeloid leukemia
Research Article October 24 2024
Cryo-EM structure of the human native plasma coagulation factor XIII complex
Research Article October 24 2024
Long-term 3-year follow-up of mosunetuzumab in relapsed or refractory follicular lymphoma after ≥2 prior therapies
Laurie H. Sehn,Nancy L. Bartlett,Matthew J. Matasar,Stephen J. Schuster,Sarit E. Assouline,Pratyush Giri,John Kuruvilla,Mazyar Shadman,Chan Y Cheah,Sascha Dietrich,Keith Fay,Matthew Ku,Loretta J. Nastoupil,Michael C. Wei,Shen Yin,Iris To,Derrick Kaufman,Antonia Kwan,Elicia Penuel,Christopher R. Bolen,Lihua Elizabeth Budde
Research Article October 23 2024
Antibiotic-induced loss of gut microbiome metabolic output correlates with clinical responses to CAR T-cell therapy
Rishika Prasad,Abdur Rehman,Lubna Rehman,Faezeh Darbaniyan,Viktoria Blumenberg,Maria-Luisa Schubert,Uria Mor,Eli Zamir,Sabine Schmidt,Tomo Hayase,Chang Chia-Chi,Lauren Kelley McDaniel,Ivonne Flores,Paolo Strati,Ranjit Nair,Dai Chihara,Luis E. Fayad,Sairah Ahmed,Swaminathan P. Iyer,Michael L Wang,Preetesh Jain,Loretta J. Nastoupil,Jason R Westin,Reetakshi Arora,Joel Gordon Turner,Fareed Khawaja,Ranran Wu,Jennifer B Dennison,Meghan Menges,Melanie Hidalgo-Vargas,Kayla M. Reid,Marco L. Davila,Peter Dreger,Felix Korell,Anita Schmitt,Mark R Tanner,Richard E. Champlin,Christopher R. Flowers,Elizabeth J Shpall,Samir Hanash,Sattva S. Neelapu,Michael Schmitt,Marion Subklewe,Johannes Fahrmann,Christoph Stein-Thoeringer,Eran Elinav,Michael D Jain,Eiko Hayase,Robert R Jenq,Neeraj Y Saini
Brief Report October 23 2024
CNS Relapse in High-Grade B-cell Lymphoma with MYC and BCL2 Rearrangements and Dark-Zone Signature-Expressing DLBCL
Brief Report October 23 2024
Soluble B-cell maturation antigen levels for disease monitoring in oligosecretory and nonsecretory relapsed multiple myeloma
Research Article October 22 2024
Conserved helical motifs in the IKZF1 disordered region mediate NuRD interaction and transcriptional repression
Research Article October 22 2024
A phase 1 study of the amino acid modulator pegcrisantaspase and venetoclax for relapsed/refractory acute myeloid leukemia
Research Article October 22 2024
Zanubrutinib, Obinutuzumab, and Venetoclax for First-Line Treatment of Mantle Cell Lymphoma with a TP53 Mutation
Anita Kumar,Jacob D. Soumerai,Jeremy S Abramson,Jeffrey A. Barnes,Philip C Caron,Shalini Chhabra,Maria Chabowska,Ahmet Dogan,Lorenzo Falchi,Clare Grieve,J. Erika Haydu,Patrick Connor Johnson,Ashlee Joseph,Hailey Kelly,Alyssa Labarre,Jennifer K Lue,Rosalba Martignetti,Joanna Mi,Alison J Moskowitz,Colette N Owens,Sean Plummer,Madeline Puccio,Gilles A. Salles,Venkatraman E Seshan,Elizabeth Simkins,Natalie Slupe,Honglei Zhang,Andrew D. Zelenetz
Review Article October 7 2024
How I use Maintenance Therapy in Acute Myeloid Leukemia
Review Article October 7 2024
How I treat Blastic Plasmacytoid Dendritic Cell Neoplasm
Research Article October 7 2024
Asciminib plus dasatinib and prednisone for Philadelphia chromosome-positive acute leukemia
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