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Research Article
November 24 2021
Genome-wide CRISPR screen identifies CDK6 as a therapeutic target in Adult T-cell leukemia/lymphoma
Takashi Ishio,Sarvesh Kumar,Joji Shimono,Anusara Daenthanasanmak,Sigrid Dubois,Yuquan Lin,Bonita R Bryant,Michael N. Petrus,Emmanuel Bachy,Da Wei Huang,Yandan Yang,Patrick L Green,Hiroo Hasegawa,Michiyuki Maeda,Hideki Goto,Tomoyuki Endo,Takashi Yokota,Kanako C. Hatanaka,Yutaka Hatanaka,Shinya Tanaka,Yoshihiro Matsuno,Yibin Yang,Satoshi Hashino,Takanori Teshima,Thomas A Waldmann,Louis M Staudt,Masao Nakagawa
Letter
November 24 2021
Antibody Response after 2 and 3 doses of SARS-CoV-2 mRNA Vaccine in Allogeneic Hematopoietic Cell Transplant Recipients
Alexis Maillard,Rabah Redjoul,Marion Klemencie,Helene Labussiere-Wallet,Amandine Le Bourgeois,Maud D'Aveni,Anne Huynh,Ana Berceanu,Tony Marchand,Sylvain P Chantepie,Carmen Botella-Garcia,Michael Loschi,Magalie Joris,Cristina Castilla-Llorente,Anne Thiebaut-Bertand,sylvie SF francois,Mathieu Leclerc,Patrice Chevallier,Stephanie Nguyen
Research Article
November 23 2021
Resolvin T-series Reduce Neutrophil Extracellular Traps
Brief Report
November 19 2021
Systemic IL-15 promotes allogeneic cell rejection in patients treated with natural killer cell adoptive therapy
Melissa M Berrien-Elliott,Michelle Becker-Hapak,Amanda F. Cashen,Miriam T. Jacobs,Pamela Wong,Mark Foster,Ethan McClain,Sweta Desai,Patrick Pence,Sarah Cooley,Claudio G Brunstein,Feng Gao,Camille N Abboud,Geoffrey L. Uy,Peter Westervelt,Meagan A Jacoby,Iskra Pusic,Keith Stockerl-Goldstein,Mark A Schroeder,John F DiPersio,Patrick Soon-Shiong,Jeffrey S. Miller,Todd A Fehniger
Research Article
November 17 2021
PP2A is a therapeutically targetable driver of cell fate decisions via a c-Myc/p21 axis in Acute Myeloid Leukemia
Swagata Goswami,Rajeswaran Mani,Jessica Nunes,Chi-ling Chiang,Kevan Zapolnik,Eileen Y Hu,Frank W. Frissora,Xiaokui M. Mo,Logan A. Walker,Pearlly S. Yan,Ralf Bundschuh,Larry Beaver,Raymond David Devine,Yo-Ting Tsai,Ann Marie Ventura,Zhiliang Xie,Min Chen,Rosa Lapalombella,Alison R. Walker,Alice S. Mims,Karilyn Larkin,Nicole Renee Grieselhuber,Chad Bennett,Mitch A. Phelps,Erin Hertlein,Gregory K Behbehani,Sumithira Vasu,John C Byrd,Natarajan Muthusamy
Brief Report
November 17 2021
Venetoclax plus Dose-Adjusted R-EPOCH (VR-EPOCH) for Richter's Syndrome
Letter
November 17 2021
DNMT3A Overgrowth Syndrome is associated with the development of hematopoietic malignancies in children and young adults
Research Article
November 17 2021
How I Treat Frontline Transplant-eligible Multiple Myeloma
Letter
November 17 2021
Clinical, Pathological and Molecular Features of Myelodysplasia Cutis
Research Article
November 15 2021
An improved index for diagnosis and mortality prediction in malignancy associated hemophagocytic lymphohistiocytosis
Adi Zoref-Lorenz,Jun Murakami,Liron Hofstetter,Swaminathan P. Iyer,Ahmad S. Alotaibi,Shehab Fareed Mohamed,Peter G. Miller,Elad Guber,Shiri Weinstein,Joanne Yacobovich,Sarah Nikiforow,Benjamin L Ebert,Adam Lane,Oren Pasvolsky,Pia Raanani,Arnon Nagler,Nancy Berliner,Naval G. Daver,Martin Ellis,Michael B. Jordan
Research Article
November 15 2021
MS4A3 Promotes Differentiation in Chronic Myeloid Leukemia by Enhancing Common β Chain Cytokine Receptor Endocytosis
Helong Zhao,Anthony D Pomicter,Anna M Eiring,Anca Franzini,Jonathan Ahmann,Jae-Yeon Hwang,Anna V. Senina,Bret Helton,Siddharth M Iyer,Dongqing Yan,Jamshid S Khorashad,Matthew S Zabriskie,Anupriya Agarwal,Hannah M Redwine,Amber D Bowler,Phillip M Clair,Shannon K. McWeeney,Brian J Druker,Jeffrey W Tyner,Derek L Stirewalt,Vivian G. Oehler,Sooryanarayana Varambally,Kristofer C Berrett,Jeffrey M Vahrenkamp,Jason Gertz,Katherine E Varley,Jerald Radich,Michael W Deininger
Research Article
November 15 2021
Phase I/Dose Expansion Trial of Brentuximab vedotin/Lenalidomide in Relapsed or Refractory Diffuse Large B-cell Lymphoma
Jeffrey Ward,Melissa M Berrien-Elliott,Felicia Gomez,Jingqin Luo,Michelle Becker-Hapak,Amanda F Cashen,Nina D. Wagner-Johnston,Kami Maddocks,Matthew Mosior,Mark Foster,Kilannin Krysiak,Alina Schmidt,Zachary L. Skidmore,Sweta Desai,Marcus P. Watkins,Anne Fischer,Malachi Griffith,Obi L. Griffith,Todd A Fehniger,Nancy L. Bartlett
Research Article
November 12 2021
Microlyse; a thrombolytic agent that targets VWF for clearance of microvascular thrombosis
Steven de Maat,Chantal Clark,Arjan D. Barendrecht,Simone Smits,Nadine D van Kleef,Hinde El Otmani,Manon Waning,Marc Vincent Adriaan van Moorsel,Michael Szardenings,Nicolas Delaroque,Kristof Vercruysse,Rolf T Urbanus,Silvie Sebastian,Peter J Lenting,Christoph Eugen Hagemeyer,Thomas Renné,Karen Vanhoorelbeke,Claudia Tersteeg,Coen Maas
Research Article
November 12 2021
Gain-of-Function Mutations in RPA1 Cause a Syndrome with Short Telomeres and Somatic Genetic Rescue
Richa Sharma,Sushree S Sahoo,Masayoshi Honda,Sophie L Granger,Charnise Goodings,Louis Sanchez,Axel Künstner,Hauke Busch,Fabian Beier,Shondra M Pruett-Miller,Marcus Valentine,Alfonso Gonzalez Fernandez,Ti-Cheng Chang,Vincent Géli,Dmitri Churikov,Sandrine Hirschi,Victor B Pastor,Melanie Boerries,Melchior Lauten,Charikleia Kelaidi,Marcin W Wlodarski,Megan Anne Cooper,Sarah K Nicholas,Jill A Rosenfeld,Sophia Polychronopoulou,Caroline Kannengiesser,Carole Saintome,Charlotte M Niemeyer,Patrick Revy,Marc S Wold,Maria Spies,Miriam Erlacher,Stéphane Coulon
Research Article
November 10 2021
The CLL12 trial: Ibrutinib versus placebo in treatment-naïve, early stage chronic lymphocytic leukemia
Petra Langerbeins,Can Zhang,Sandra Robrecht,Paula Cramer,Moritz Fürstenau,Othman Al-Sawaf,Julia von Tresckow,Anna Maria Fink,Karl-Anton Kreuzer,Ursula Vehling-Kaiser,Eugen Tausch,Lothar Müller,Michael J. Eckart,Rudolf Schlag,Werner Freier,Tobias Gaska,Christina Balser,Marcel Reiser,Martina Stauch,Clemens-Martin Wendtner,Kirsten Fischer,Stephan Stilgenbauer,Barbara Eichhorst,Michael Hallek
Brief Report
November 10 2021
Germline GATA1s generating mutations predispose to leukemia with acquired trisomy 21 and Down syndrome-like phenotype
Review Article
November 10 2021
Primary Cutaneous Lymphoma: Recommendations for Clinical Trial Design and Staging Update from the ISCL, USCLC, and EORTC
Elise A. Olsen,Sean Whittaker,Rein Willemze,Lauren Pinter-Brown,Francine M Foss,Larisa J Geskin,Lawrence HOWARD Schwartz,Steven M. Horwitz,Joan Guitart,John Zic,Youn H. Kim,Gary S. Wood,Madeleine Duvic,Weiyun Z. Ai,Michael Girardi,Alejandro Gru,Emmanuella Guenova,Emmilia Hodak,Richard T. Hoppe,Werner Kempf,Ellen J Kim,Mary Jo Lechowicz,Pablo L. Ortiz-Romero,Evangelia Papadavid,Pietro Quaglino,Mark R Pittelkow,H. Miles Prince,Jose Antonio Sanches,Makoto Sugaya,Maarten H. Vermeer,Jasmine Zain,Robert Knobler,Rudolf Stadler,Martine Bagot,Julia J Scarisbrick
Letter
November 10 2021
Neutrophil and platelet increases with luspatercept in lower-risk MDS: secondary endpoints from the MEDALIST trial
Letter
November 8 2021
COVID-19 in vaccinated adult patients with hematological malignancies. Preliminary results from EPICOVIDEHA
Livio Pagano,Jon Salmanton-García,Francesco Marchesi,Alberto Lopez-Garcia,Sylvain Lamure,Federico Itri,Maria Gomes da Silva,Giulia Dragonetti,Iker Falces-Romero,Jaap van Doesum,Uluhan Sili,Jorge Labrador,Maria Calbacho,Yavuz Bilgin,Barbora Weinbergerová,Laura Milena Serrano Gomez,Josep-Maria Ribera,Sandra Malak,Jose Loureiro-Amigo,Andreas Glenthøj,Raul Cordoba,Raquel Nunes Rodrigues,Tomas Jose Gonzalez-Lopez, Dr,Linda Katharina Karlsson,Maria-Jose Jimenez,José-Ángel Hernández-Rivas,Ozren Jaksic,Zdenek Racil,Alessandro Busca,Paolo Corradini,Martin Hoenigl,nikolai Klimko,Philipp Koehler,Antonio Pagliuca,Francesco Passamonti,Oliver Cornely
Research Article
November 5 2021
Infection risk and prophylaxis in patients with lymphoid cancer
Research Article
November 5 2021
The Similarity of Class II HLA Genotypes Defines Patterns of Autoreactivity in Idiopathic Bone Marrow Failure Disorders
Simona Pagliuca,Carmelo Gurnari,Hassan Awada,Ashwin Kishtagari,Sunisa Kongkiatkamon,Laila Terkawi,Misam Zawit,Yihong Guan,Thomas LaFramboise,Babal K Jha,Bhumika J Patel,Betty K Hamilton,Navneet S Majhail,Sofie Lundgren,Satu Mustjoki,Yogen Saunthararajah,Valeria Visconte,Timothy Chan,Chao-Yie Yang,Tobias Lenz,Jaroslaw P. Maciejewski
Research Article
November 2 2021
ALK-positive histiocytosis: a new clinicopathologic spectrum highlighting neurologic involvement and responses to ALK inhibition
Paul Geraeds Kemps,Jennifer Picarsic,Benjamin H. Durham,Zofia Hélias-Rodzewicz,Laura Sophia Hiemcke-Jiwa, Dr,Cor van den Bos,Marianne D. van de Wetering,Carel J.M. van Noesel,Jan AM van Laar,Robert M. Verdijk,Uta E. Flucke,Pancras C.W. Hogendoorn,F.J. Sherida H. Woei-A-Jin,Raf Sciot,Andreas Beilken,Friedrich Feuerhake,Martin Ebinger,Robert Möhle,Falko Fend,Antje Bornemann,Verena Wiegering,Karen Ernestus,Tina Méry,Olga Gryniewicz-Kwiatkowska,Bozenna Dembowska-Baginska,Dmitry A. Evseev,Vsevolod Potapenko,Vadim V. Baykov,Stefania Gaspari,Sabrina Rossi,Marco Gessi,Gianpiero Tamburrini,Sébastien Héritier,Jean Donadieu,Jacinthe Bonneau-Lagacherie,Claire Lamaison,Laure Farnault,Sylvie Fraitag,Marie-Laure Jullie,Julien Haroche, MD, PhD,Matthew Collin,Jackie Allotey,Majid Madni,Kerry Turner,Susan Picton,Pasquale M. Barbaro,Alysa Poulin,Ingrid S. Tam,Dina El Demellawy,Brianna Empringham,James A. Whitlock,Aditya Raghunathan,Amy A. Swanson,Mariko Suchi,Jon M. Brandt,Nabeel R. Yaseen,Joanna L. Weinstein,Irem Eldem,Bryan A. Sisk,Vaish Sridhar,Mandy M Atkinson,Lucas R. Massoth,Jason L. Hornick,Sanda Alexandrescu,Kee Kiat Yeo,Kseniya Petrova-Drus,Stephen Z. Peeke,Laura Munoz-Arcos,Daniel G. Leino,David Douglas Grier,Robert Lorsbach,Somak Roy,Ashish R. Kumar,Shipra Garg,Nishant Tiwari,Kristian T. Schafernak,Michael M Henry,Astrid G.S. van Halteren,Oussama Abla,Eli L. Diamond,Jean-François Emile
Research Article
November 2 2021
How I Treat High-risk Multiple Myeloma
Review Article
November 1 2021
Hemostatic and thrombotic disorders in the pediatric patient
Research Article
November 1 2021
HLA associations, somatic loss of HLA expression, and clinical outcomes in immune aplastic anemia
Research Article
November 1 2021
HLA Informs Risk Predictions after Haploidentical Stem Cell Transplantation with Post-transplantation Cyclophosphamide
Ephraim J Fuchs,Shannon R McCurdy,Scott R Solomon,Tao Wang,Megan M. Herr,Dipenkumar Modi,Michael Richard Grunwald,Taiga Nishihori,Michelle Kuxhausen,Stephanie Fingerson,Caroline McKallor,Asad Bashey,Yvette L Kasamon,Yung-Tsi Bolon,Ayman Saad,Joseph P McGuirk,Sophie Paczesny,Shahinaz M Gadalla,Steven GE Marsh,Bronwen E. Shaw,Stephen R. Spellman,Stephanie J Lee,Effie W Petersdorf
Review Article
November 1 2021
2021 Update Measurable Residual Disease in Acute Myeloid Leukemia: European LeukemiaNet Working Party Consensus Document
Michael Heuser,Sylvie D Freeman,Gert J Ossenkoppele,Francesco Buccisano,Christopher S Hourigan,Lok Lam Ngai,Jesse Marc Tettero,Costa Bachas,Constance Baer,Marie C Béné,Veit Buecklein,Anna Czyz,Barbara Denys,Richard Dillon,Michaela Feuring-Buske,Monica L Guzman,Torsten Haferlach,Lina Han,Julia K Herzig,Jeffrey L Jorgensen,Wolfgang Kern,Marina Y. Konopleva,Francis Lacombe,Marta Libura,Agata Majchrzak,Luca Maurillo,Yishai Ofran,Jan Philippé,Adriana Plesa,Claude Preudhomme,Farhad Ravandi,Christophe Roumier,Marion Subklewe,Felicitas Thol,Arjan A van de Loosdrecht,Bert A. van der Reijden,Adriano Venditti,Agnieszka Wierzbowska,Peter J.M. Valk,Brent L. Wood,Roland B Walter,Christian Thiede,Konstanze Döhner,Gail J. Roboz,Jacqueline Cloos
Research Article
November 1 2021
The histone lysine acetyltransferase HBO1 (KAT7) regulates hematopoietic stem cell quiescence and self-renewal
Letter
October 29 2021
Abatacept is useful in auto-immune cytopenia with immunopathologic manifestations caused by CTLA-4 defects
Chloé Dhunputh,Stéphane Ducassou,Helder Fernandes,Capucine Picard,Frédéric Rieux-Laucat,Jean-François Viallard,Estibaliz Lazaro, Pr,Hermine Olivier,Mathieu Jouvray,Irène Machelart,Anne Lambilliotte,Marion Malphettes,Despina Moshous,Bénédicte Neven,Alexandra Gauthier,Nathalie Garnier,Thierry M Leblanc,Judith Landman-Parker,Guy Leverger,Nathalie Aladjidi
Review Article
October 26 2021
Primary Central Nervous System Lymphoma
Research Article
October 26 2021
Heightened turnover and failed maturation of monocyte-derived macrophages in murine Chronic Granulomatous Disease
Research Article
October 26 2021
Phase 1 TRANSCEND CLL 004 study of lisocabtagene maraleucel in patients with relapsed/refractory CLL or SLL
Research Article
October 26 2021
Asxl1loss cooperates with oncogenic Nras in mice to reprogram immune microenvironment and drive leukemic transformation
Xiaona You,Fabao Liu,Moritz Binder,Alexis Vedder,Terra L Lasho,Zhi Wen, MD & PhD,Xin GAO,Evan Flietner,Adhithi Rajagopalan,Yun Zhou,Christy M. Finke,Abhishek A Mangaonkar,Ruiqi Liao,Guangyao Kong,Erik A. Ranheim,Nathalie M Droin,Anthony M. Hunter,Sergey Nikolaev,Maria E. Balasis,Omar Abdel-Wahab,Ross L. Levine,Britta Will,Kalyan Vara Ganesh Nadiminti,David T Yang,Klaus Geissler,Eric Solary,Wei Xu,Eric Padron,Mrinal M Patnaik,Jing Zhang
Research Article
October 26 2021
Perturbed NK Cell Homeostasis Associated with Disease Severity in Chronic Neutropenia
Research Article
October 25 2021
Two novel high-risk adult B-cell acute lymphoblastic leukemia subtypes with high expression of CDX2 and IDH1/2 mutations
Takahiko Yasuda,Masashi Sanada,Masahito Kawazu,Shinya Kojima,Shinobu Tsuzuki,Hiroo Ueno,Eisuke Iwamoto,Yuka Iijima-Yamashita,Tomomi Yamada,Takashi Kanamori,Rieko Nishimura,Yachiyo Kuwatsuka,Satoru Takada,Masatsugu Tanaka,Shuichi Ota,Nobuaki Dobashi,Etsuko Yamazaki,Asao Hirose,Tohru Murayama,Masahiko Sumi,Shinya Sato,Naoyuki Tange,Yukinori Nakamura,Yuna Katsuoka,Emiko Sakaida,Toyotaka Kawamata,Hiroatsu Iida,Yuichi Shiraishi,Yasuhito Nannya,Seishi Ogawa,Masafumi Taniwaki,Norio Asou,Yoshihiro Hatta,Hitoshi Kiyoi,Itaru Matsumura,Keizo Horibe,Hiroyuki Mano,Tomoki Naoe,Yasushi Miyazaki,Fumihiko Hayakawa
Review Article
October 25 2021
COVID-19 Convalescent plasma
Research Article
October 25 2021
PLCG1 is required for AML1-ETO leukemia stem cell self-renewal
Tina M. Schnoeder,Adrian Schwarzer,Ashok Kumar Jayavelu,Chen-Jen Hsu,Joanna Kirkpatrick,Konstanze Döhner,Florian Perner,Theresa Eifert,Nicolas Huber,Patricia Arreba-Tutusaus,Anna Dolnik,Salam A Assi,Monica Nafria,Lu Jiang,Yu-Ting Dai,Zhu Chen,Sai-Juan Chen,Sophie G. Kellaway,Anetta Ptasinska,Elizabeth S. Ng,Edouard G. Stanley,Andrew G. Elefanty,Marcus Buschbeck,Holger Bierhoff,Steffen Brodt,Georg Matziolis,Klaus-Dieter Fischer,Andreas Hochhaus,Chun-Wei Chen,Olaf Heidenreich,Matthias Mann,Steven W Lane,Lars Bullinger,Alessandro Ori,Björn von Eyss,Constanze Bonifer,Florian Heidel
Research Article
October 25 2021
Whole-genome landscape of adult T-cell leukemia/lymphoma
Yasunori Kogure,Takuro Kameda,Junji Koya,Makoto Yoshimitsu,Kisato Nosaka,Jun-ichirou Yasunaga,Yoshitaka Imaizumi,Mizuki Watanabe,Yuki Saito,Yuta Ito,Marni B McClure,Mariko Tabata,Sumito Shingaki,Kota Yoshifuji,Kenichi Chiba,Ai Okada,Nobuyuki Kakiuchi,Yasuhito Nannya,Ayako Kamiunten,Yuki Tahira,Keiichi Akizuki,Masaaki Sekine,Kotaro Shide,Tomonori Hidaka,Yoko Kubuki,Akira Kitanaka,Michihiro Hidaka,Nobuaki Nakano,Atae Utsunomiya,R. Alejandro Sica,Ana Acuna-Villaorduna,Murali Janakiram,Urvi A Shah,Juan Carlos Ramos,Tatsuhiro Shibata,Kengo Takeuchi,Akifumi Takaori-Kondo,Yasushi Miyazaki,Masao Matsuoka,Kenji Ishitsuka,Yuichi Shiraishi,Satoru Miyano,Seishi Ogawa,B.Hilda Ye,Kazuya Shimoda,Keisuke Kataoka
Research Article
October 22 2021
Therapeutic options for relapsed/refractory mantle cell lymphoma
Letter
October 20 2021
Humoral and cellular responses after COVID-19 vaccination in anti-CD20 treated lymphoma patients
Research Article
October 19 2021
All-trans retinoic acid plus low-dose rituximab vs low-dose rituximab in corticosteroid-resistant or relapsed ITP
Brief Report
October 18 2021
Gene expression-based model predicts outcome in children with intermediate-risk classical Hodgkin lymphoma
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