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Research Article September 30 2022
The proto-oncogene TCL1A deregulates cell cycle and genomic stability in CLL
Johanna Stachelscheid,Qu Jiang,Christoph Markus Aszyk,Kathrin Warner,Nadine Bley,Tony A. Müller,Olga Vydzhak,Konstantinos Symeonidis,Giuliano Crispatzu,Petra Mayer,Stuart James Blakemore,Gudrun Goehring,Sebastian Newrzela,Stephanie Hippler,Sandra Robrecht,Karl-Anton Kreuzer,Christian P Pallasch,Marcus Krüger,Axel Lechner,Kirsten Fischer,Stephan Stilgenbauer,Dirk Beutner,Michael Hallek,Daniel Auguin,Stefan Hüttelmaier,Johannes Bloehdorn,Elena Vasyutina,Marco Herling
Letter September 30 2022
Description of a novel subtype of acute myeloid leukemia defined by recurrent CBFB insertions
Georgina Ryland,Masayuki Umeda,Linda Holmfeldt,Sören Lehmann,Morten Krogh Herlin,Jing J. Ma,Mahsa Khanlari,Jeffrey E. Rubnitz,Rhonda E. Ries,Hansen J Kosasih,Paul G Ekert,Hwee Ngee Goh,Ing Soo Tiong,Sean M Grimmond,Claudia Haferlach,Ryan B Day,Timothy J Ley,Soheil Meshinchi,Xiaotu Ma,Piers Blombery,Jeffery M Klco
Research Article September 23 2022
An Open-Label, Single-Arm, Phase 2 Trial of Valemetostat in Relapsed or Refractory Adult T-Cell Leukemia/Lymphoma
Koji Izutsu,Shinichi Makita,Kisato Nosaka,Makoto Yoshimitsu,Atae Utsunomiya,Shigeru Kusumoto,Satoko Morishima,Kunihiro Tsukasaki,Toyotaka Kawamata,Takaaki Ono,Shinya Rai,Hiroo Katsuya,Jun Ishikawa,Hironori Yamada,Kazunobu Kato,Masaya Tachibana,Yasuyuki Kakurai,Nobuaki Adachi,Kensei Tobinai,Kentaro Yonekura,Kenji Ishitsuka
Letter September 23 2022
Hybrid immunity in immunocompromised patients with CLL after SARS-CoV-2 infection followed by booster mRNA vaccination
Review Article September 21 2022
Genomic Profiling for Clinical Decision Making in Myeloid Neoplasms and Acute Leukemia
Eric J Duncavage,Adam Bagg,Robert P. Hasserjian,Courtney D. DiNardo,Lucy A. Godley,Ilaria Iacobucci,Siddhartha Jaiswal,Luca Malcovati,Alessandro M. Vannucchi,Keyur P Patel,Daniel A. Arber,Maria E Arcila,Rafael Bejar,Nancy Berliner,Michael J. Borowitz,Susan Branford,Anna L Brown,Catherine A Cargo,Hartmut Döhner,Brunangelo Falini,Guillermo Garcia-Manero,Torsten Haferlach,Eva Hellström-Lindberg,Annette S. Kim,Jeffery M Klco,Rami S. Komrokji,Mignon L. Loh,Sanam Loghavi,Charles G. Mullighan,Seishi Ogawa,Ayalew Tefferi,Elli Papaemmanuil,Andreas Reiter,David Morrall Ross,Michael R Savona,Akiko Shimamura,Radek C. Skoda,Francesc Sole,Richard M. Stone,Attilio Orazi,Matthew J Walter,David Wu,Benjamin L. Ebert,Mario Cazzola
Research Article September 21 2022
MRD dynamics during maintenance for improved prognostication of 1280 myeloma patients in TOURMALINE-MM3 and -MM4 trials
Research Article September 20 2022
A MIR17HG-derived Long Noncoding RNA Provides an Essential Chromatin Scaffold for Protein Interaction and Myeloma Growth
Eugenio Morelli,Mariateresa Fulciniti,Mehmet K. Samur,Caroline Ribeiro,Leon Wert-Lamas,Jonathan E Henninger,Annamaria Gulla,Anil Aktas Samur,Katia Todoerti,Srikanth Talluri,Woojun D. Park,Cinzia Federico,Francesca Scionti,Nicola Amodio,Giada Bianchi,Megan Johnstone,Na Liu,Doriana Gramegna,Domenico Maisano,Nicola A Russo,Charles Y. Lin,Yu-Tzu Tai,Antonino Neri,Dharminder Chauhan,Teru Hideshima,Masood A Shammas,Pierfrancesco Tassone,Sergei Gryaznov,Richard Young,Kenneth C. Anderson,Carl D. Novina,Massimo Loda,Nikhil C. Munshi
Research Article September 20 2022
Breakthrough COVID-19 in vaccinated patients with hematologic malignancies: results from EPICOVIDEHA survey
Livio Pagano,Jon Salmanton-García,Francesco Marchesi,Ola Blennow,Maria Gomes da Silva,Andreas Glenthøj,Jaap A. van Doesum,Yavuz M Bilgin,Alberto Lopez-Garcia,Federico Itri,Raquel Nunes Rodrigues,Barbora Weinbergerová,Francesca Farina,Giulia Dragonetti,Caroline Berg Venemyr,Jens Van Praet,Ozren Jaksic,Toni Valkovic,Iker Falces-Romero,Sonia Martin-Perez,Moraima Jiménez,Julio Davila-Valls,Martin Schonlein,Emanuele Ammatuna,Stef Meers,Mario Delia,Zlate Stojanoski,Anna Nordlander,Tobias Lahmer,László Imre Pinczés,Caterina Buquicchio,Klára Piukovics,Irati Ormazabal-Velez,Nicola Stefano Fracchiolla,Michail Samarkos,Gustavo-Adolfo Mendez,José-Ángel Hernández-Rivas,Ildefonso Espigado,Martin Cernan,Verena Petzer,Sylvain Lamure,Roberta Di Blasi,Joyce Marques de Almeida,Michelina Dargenio,Monika Maria Biernat, Dr,Mariarita Sciumè,Cristina de Ramón,Nick Alexander De Jonge,Josip Batinic,Avinash Aujayeb,Monia Marchetti,Guillemette Fouquet,Noemi Fernández Escalada,Giovanni Paolo Maria Zambrotta,Maria Vittoria Sacchi,Anna Guidetti,Fatih Demirken,Lucia Prezioso,Zdenek Racil,Marcio Nucci,Miloš Mladenovic,Raphaël Lievin,Michaela Hanakova,Stefanie K Grafe,Uluhan Sili,Marina Machado,Chiara Cattaneo,Tatjana Adzic-Vukicevic,Luisa Verga,Jorge Labrador,Laman Rahimli,Matteo Bonanni,Francesco Passamonti,Antonio Pagliuca,Paolo Corradini,Martin Hoenigl,Philipp Koehler,Alessandro Busca,Oliver A. Cornely
Research Article September 19 2022
Outcomes of patients with aggressive B-Cell lymphoma after failure of anti-CD19 CAR T-Cell Therapy: A DESCAR-T analysis
Roberta Di Blasi,Steven Le Gouill,Emmanuel Bachy,Guillaume Cartron,David Beauvais,Fabien Le Bras,François-Xavier Gros,Sylvain Choquet,Pierre Bories,Pierre Feugier,Olivier Casasnovas,Jacques-Olivier Bay,Mohamad Mohty,Magalie Joris,Thomas Gastinne,Pierre Sesques,Jean-Jacques Tudesq,Laetitia Vercellino,Franck Morschhauser,Elodie Gat,Florence Broussais,Roch Houot,Catherine Thieblemont
Research Article September 19 2022
Missense mutations in PIEZO1, encoding the Piezo1 mechanosensor protein, define the Er red blood cell antigens
Vanja Karamatic Crew,Louise A Tilley,Timothy J Satchwell,Samah A AlSubhi,Benjamin Jones,Frances A Spring,Piers J Walser,Catarina Martins Freire,Nicoletta Murciano,Maria Giustina Rotordam,Svenja J Woestmann,Marwa Hamed,Reem Alradwan,Mouza AlKhrousey,Ian Skidmore,Sarah Lewis,Shimon Hussain,Jane Jackson,Tom Latham,Mark D Kilby,William Arthur Lester,Nadine Becker,Markus Rapedius,Ashley Mark Toye,Nicole M Thornton
Research Article September 19 2022
Malignant T cells induce skin barrier defects through cytokine-mediated JAK/STAT signalling in cutaneous T-cell lymphoma
Maria Gluud,Emil Marek Heymans Pallesen,Terkild B. Buus,Lise M. R. Gjerdrum,Lise M. Lindahl,Maria R. Kamstrup,Michael Bzorek,Maria Danielsen,Rikke Bech,Madalena N Monteiro,Edda Blümel,Andreas Willerslev-Olsen,Anders Lykkebo-Velløe,Chella Krishna Vadivel,Thorbjørn Krejsgaard,Charlotte M. Bonefeld,Carsten Geisler,Jürgen C. Becker,Sergei B. Koralov,Lars Iversen,Thomas Litman,Anders Woetmann,Niels Odum
Research Article September 16 2022
Tracing the evolutionary history of blood cells to the unicellular ancestor of animals
Letter September 16 2022
Long-term follow-up of VIALE-C in patients with untreated AML ineligible for intensive chemotherapy
Andrew H. Wei,Panayiotis Panayiotidis,Pau Montesinos,Kamel Laribi,Vladimir Ivanov, MD,Inho Kim,Jan Novak,Rebecca Champion,Walter Fiedler,Maria Pagoni,Julie Bergeron, MD,Stephen Ting,JingZhou Hou,Achilles Anagnostopoulos,Andrew McDonald,Vidhya Murthy,Takahiro Yamauchi,Jianxiang Wang,Qi Jiang,Yan Sun,Brenda Chyla,Wellington L Mendes,Courtney D. DiNardo
Letter September 16 2022
iPLAT1: The first-in-human clinical trial of iPSC-derived platelets as a phase 1 autologous transfusion study
Naoshi Sugimoto,Junya Kanda,Sou Nakamura,Toshiyuki Kitano,Masakatsu Hishizawa,Tadakazu Kondo,Shin Shimizu, Mr.,Akiko Shigemasa,Hideyo Hirai,Yasuyuki Arai,Manabu Minami,Harue Tada,Dai Momose,Ki-Ryang Koh,Masayuki Nogawa,Naohide Watanabe,Shinichiro Okamoto,Makoto Handa,Akira Sawaguchi,Nobuki Matsuyama,Mitsunobu Tanaka,Tomoya Hayashi,Akihiro Fuchizaki,Yoshihiko Tani,Akifumi Takaori-Kondo,Koji Eto
Research Article September 15 2022
Dabrafenib plus trametinib in patients with relapsed/refractory BRAF V600E mutation-positive hairy cell leukemia
Research Article September 15 2022
von Willebrand Factor-binding aptamer rondoraptivon pegol as treatment for severe and non-severe hemophilia A
Research Article September 15 2022
Recombinant Erwinia Asparaginase (JZP458) in Acute Lymphoblastic Leukemia: Results from the Phase 2/3 AALL1931 Study
Review Article September 12 2022
The end of the beginning: Application of single cell sequencing to chronic lymphocytic leukemia (CLL)
Research Article September 12 2022
Efficacy and safety of cilta-cel in patients with progressive MM after exposure to other BCMA-targeting agents
Adam D. Cohen,Maria-Victoria Mateos,Yael C. Cohen,Paula Rodriguez-Otero,Bruno Paiva,Niels W.C.J. van de Donk,Thomas G. Martin,Attaya Suvannasankha,Kevin C. De Braganca,Christina Corsale,Jordan M. Schecter,Helen Varsos,William Deraedt,Liwei Wang,Martin Vogel,Tito Roccia,Xiaoying Xu,Pankaj Mistry,Enrique Zudaire,Muhammad Akram,Tonia Nesheiwat,Lida Pacaud,Irit Avivi,Jesus San-Miguel
Research Article September 12 2022
EVI1 drives leukemogenesis through aberrant ERG activation
Research Article September 12 2022
Effective treatment of low risk acute GVHD with itacitinib monotherapy
Aaron M. Etra,Alexandra Capellini,Amin M Alousi,Monzr M. Al Malki,Hannah K Choe,Zachariah DeFilipp,William J Hogan,Carrie L. Kitko,Francis Ayuketang Ayuk,Janna Baez,Isha Gandhi,Stelios Kasikis,Sigrun Gleich,Elizabeth Hexner,Matthias Hoepting, Dr. med,Urvi Kapoor,Steven Kowalyk,Deukwoo Kwon,Amelia Langston,Marco Mielcarek,George Morales,Umut Özbek,Muna Qayed,Ran Reshef,Wolf Roesler,Nikolaos Spyrou,Rachel Young,Yi-Bin Chen,James LM Ferrara,John E Levine
Letter September 12 2022
Risk Factors for Severe Infection and Mortality in COVID-19 and Monoclonal Gammopathy of Undetermined Significance
Matthew Ho,Saurabh Zanwar,Francis K Buadi,Sikander Ailawadhi,Jeremy T Larsen,P Leif Bergsagel,Moritz Binder,Asher A Chanan-Khan,David Dingli,Angela Dispenzieri,Rafael Fonseca,Morie A Gertz,Wilson I Gonsalves,Ronald S. Go,Suzanne R Hayman,Prashant Kapoor,Taxiarchis V. Kourelis,Martha Q Lacy,Nelson Leung,Yi Lin,Eli Muchtar,Vivek Roy,Taimur Sher,Rahma Warsame,Amie L Fonder,Miriam A Hobbs,Yi Lisa Hwa,Robert A Kyle,S. Vincent Rajkumar,Shaji K Kumar
Letter September 12 2022
Clonal Hematopoiesis of Indeterminate Potential and Risk of Death from COVID-19
Peter Grant Miller,Geoffrey Fell,Brody Foy,Allison Scherer,Christopher J. Gibson,Adam S. Sperling,Bala Bharathi Burugula,Tetsushi Nakao,Md Mesbah Uddin,Hailey Warren,Lynn Bry,Olga Pozdnyakova,Matthew J Frigault,Alexander G. Bick,Donna Neuberg,John M Higgins,Michael Mansour,Pradeep Natarajan,Annette S. Kim,Jacob Kitzman,Benjamin L. Ebert
Research Article September 12 2022
Tγδ LGL LEUKEMIA IDENTIFIES A SUBSET WITH MORE SYMPTOMATIC DISEASE: ANALYSIS OF AN INTERNATIONAL COHORT OF 137 PATIENTS
Gregorio Barila',Angela Grassi,HeeJin Cheon,Antonella Teramo,Giulia Calabretto,Jasmanet Singh Chahal,Cristina Vicenzetto,Julia Almeida,Bryna C Shemo,Min Shi,Vanessa Rebecca Rebecca Gasparini,Noemi Munoz-Garcia,Cedric Pastoret,Hideyuki Nakazawa,Kazuo Oshimi,Lubomir Sokol,Fumihiro Ishida,Thierry Lamy,Alberto Orfao,William George Morice,Thomas Loughran,Gianpietro Semenzato,Renato Zambello
Research Article September 9 2022
Macrophage- and BCR- but not TLR-derived signals support the growth of CLL and Richter Syndrome murine models in vivo
Research Article September 9 2022
Detecting measurable residual disease beyond 10-4 through an IGHV leader-based NGS approach improves prognostic stratification in CLL
Research Article September 9 2022
Trafficking between clonally related peripheral T helper cells and tissue-resident T helper cells in chronic GVHD
Research Article September 6 2022
A randomized trial of blood donor iron repletion on red cell quality for transfusion and donor cognition and wellbeing
Eldad A Hod,Gary M Brittenham,Zachary C Bitan,Yona Feit,Jordan I Gaelen,Francesca La Carpia,Luke A Sandoval,Alice T Zhou,Mark Soffing,Akiva Mintz,Joseph Schwartz,Connie Eng,Marta Scotto,Elise Caccappolo,Christian Habeck,Yaakov Stern,Donald J McMahon,Debra Kessler,Beth Shaz,Richard O. Francis,Steven L Spitalnik
Research Article September 2 2022
Perioperative diagnosis and impact of acquired von Willebrand syndrome in infants with congenital heart disease
Research Article September 2 2022
Epo-IGF1R crosstalk expands stress-specific progenitors in regenerative erythropoiesis and myeloproliferative neoplasm
Research Article September 2 2022
Immune thrombocytopenia and pregnancy: an exposed/non-exposed cohort study
Stephanie Guillet,Valentine Loustau,Emmanuelle Boutin,Anissa Zarour,Thibault Comont,Odile Souchaud-Debouverie,Nathalie Costedoat,Brigitte Pan-Petesch,Delphine Gobert,Stéphane Cheze,Jean-François Viallard,Anne-Sophie Morin,Gaetan Sauvetre,Manuel Cliquennois,Bruno Royer,Agathe Masseau,Louis Terriou,Claire Fieschi,Olivier Lambotte,Stéphane Girault,Bertrand Lioger,Sylvain Audia,Karim Sacre,Jean-Christophe Lega,Vincent Langlois,Alexandra Benachi,Corentin Orvain,Alain Devidas,Sebastien Humbert,Nicolas Gambier,Marc Ruivard,Virginie Zarrouk,Mikael Ebbo,Lise Willems,Lauriane Segaux,Matthieu Mahevas,Bassam Haddad,Marc Michel,Florence Canoui-Poitrine,Bertrand Godeau
Research Article August 31 2022
Engineering T cells to suppress acute GvHD and leukemia relapse after allogeneic hematopoietic stem cell transplantation
Research Article August 31 2022
A UNIQUE IMMUNE SIGNATURE IN BLOOD SEPARATES THERAPY-REFRACTORY FROM THERAPY-RESPONSIVE ACUTE GRAFT-VERSUS-HOST DISEASE
Research Article August 30 2022
Hypoxia and low temperature up-regulate transferrin to induce hypercoagulability at high altitude
Research Article August 30 2022
Normalization of cerebral hemodynamics following hematopoietic stem cell transplant in children with sickle cell disease
Letter August 30 2022
CD39/CD73 dysregulation and adenosine metabolism contribute to T cell immunosuppression in patients with Sézary syndrome
Research Article August 29 2022
Chronic Conditions, Late Mortality and Health Status After Childhood AML: A Childhood Cancer Survivor Study Report
Research Article August 26 2022
S100A8/A9 drives the formation of procoagulant platelets through GPIbα
Martina Colicchia,Waltraud C. Schrottmaier,Gina Perrella,Jasmeet S. Reyat,Jenefa Begum,Alexandre Slater,Joshua Price,Joanne C Clark,Zhaogong Zhi,Megan Simpson,Joshua Bourne,Natalie S. Poulter,Abdullah Obaid Khan,Phillip Lindsay Ross Nicolson,Matthew Richard Pugh,Paul Harrison,Asif J Iqbal,George E. Rainger,Steve P Watson,Mark R. Thomas,Nicola J Mutch,Alice Assinger,Julie Rayes
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