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First Edition

Review Article July 11 2025
How I Treat Pediatric Pulmonary Embolism
Ayesha Zia,Neil A Goldenberg,Madhvi Rajpurkar
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Research Article July 11 2025
Profiling the spatial architecture of multiple myeloma in human bone marrow trephine biopsy specimens with spatial transcriptomics
Raymond K.H. Yip,Jeremy Er,Lei Qin,Quoc Hoang Nguyen,Allan Motyer,Joel S Rimes,Amanda Light,Ruvimbo D Mishi,Ling Ling,Casey J.A. Anttila,Ellen Tsui,Daniela Amann-Zalcenstein,Mark R Dowling,Kelly L. Rogers,Rory Bowden,Yunshun Chen,Simon J Harrison,Edwin D Hawkins
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Research Article July 10 2025
Loss of DCAF8 impairs hematopoietic stem cell function with cellular senescence via the DOCK11-CDC42 axis
Pengfei Xu,Xiuli Zhang,Donghe Li,Bo Jiao,Jiawei Nie,Yi Huang,Zhizhou Xia,Jiaoyang Li,Yuqing Dan,Xu Huang,Lei Yan,Rui Zhang,Wei Huang,Xinru Wang,Shiyu Ji,Yong Cang,Ruibao Ren,Ping Liu
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Research Article July 10 2025
Thrombocytopenia in myelofibrosis is characterized by inflammatory megakaryocytes with reduced G6B expression
Lilian Varricchio,Gohar Mosoyan,Sebastian El Ghaity-Beckley,Md. Babu Mia,Shivani Handa,Christian Salib,John O. Mascarenhas,Ronald Hoffman
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Research Article July 10 2025
Matched donor allogeneic CAR-T for adult B-ALL: toxicity, efficacy, repeat dosing, and the importance of lymphodepletion
Claire Roddie,Juliana Dias,Maeve O'Reilly,Mahnaz Abbasian,Amaia Cadinanos-Garai,Ketki Vispute,Leticia Bosshard-Carter,Marina Mitsikakou,Eftychia Charalambous,Vedika Mehra,Harriet Roddy,Gordon Weng-Kit Cheung,John A. Hartley,Nasir Galal Mahmoud,Leah Ensell,Yashma Patel,Maria A. V. Marzolini,Farzin Farzaneh,Lauren Nickolay,Nourredine Himoudi,Farhatullah Syed,Bilyana Popova,Sevasti Galani,Alexander Day,Mark W Lowdell,Karl S Peggs
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Review Article July 10 2025
Structure and interactions of the proteins from the contact system
Jonas Emsley,Yujie Ma,Joost C.M. Meijers
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Research Article July 10 2025
Boosting CAR T-Cell Efficacy by Blocking Proteasomal Degradation of Membrane Antigens
Leonie Rieger,Kilian Irlinger,Franziska Füchsl,Marlene Tietje,Anna Purcarea,Nicolas Mathis Barbian,Melanie Faber,Carolin Vogelsang,Lisa Pfeuffer,Sonja Stotz,Oleksandra Karpiuk,Tobias Schulze,Abirami Augsburger,Nadine Glaisner,Verena Konetzki,Sabrina Friedel,Andrej Besse,Lenka Besse,Christoph Driessen,Maike Buchner,Kristina Schwamborn,Katja Steiger,Piero Giansanti,Sebastian Theurich,Johannes M. Waldschmidt,Klaus Martin Kortüm,Michael Hudecek,Hermann Einsele,Marion Högner,Bernhard Kuster,Angela Krackhardt,Judith S. Hecker,Florian Bassermann
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Research Article July 10 2025
A noncoding mutation in the NOTCH1 gene initiates oncogenic NOTCH signaling via wild-type NICD stabilization in CLL
Min Guo,Tugba Memis,Alena Sophie Ehrmann,Anselm Pittrof,Bernd Baumann,Francesca Ferrante,Eugen Tausch,Kirsten Fischer,Hartmut Döhner,Tilman Borggrefe,Stephan Stilgenbauer,Ulrich Pannicke,Klaus Schwarz,Daniel Mertens,Franz Oswald
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Review Article July 7 2025
Immune Alterations in Myeloma Evolution and Outcomes: Quo Vadis?
Madhav V. Dhodapkar,Bruno Paiva
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Research Article July 7 2025
Outcomes of Allogeneic HCT in Hodgkin Lymphoma in the Era of Checkpoint Inhibitors: A Joint CIBMTR and EBMT Analysis.
Miguel-Angel Perales,Farrukh T Awan,Ariane Boumendil,Jinalben Patel,Luca Castagna,Emanuele Angelucci,Herve Finel,Alexander D. Kulagin,Bertram Glass,Paolo Corradini,Alex F. Herrera,Didier Blaise,Mohamed A Kharfan-Dabaja,Khalid Halahleh,Sairah Ahmed,Carmen Martinez,Sebastian Giebel,Silvia Montoto,Richard J. Jones,Nausheen Ahmed,Ryan C Lynch,Marcos J de Lima,Mazyar Shadman,Craig S. Sauter,Kwang Woo Ahn,Mehdi Hamadani,Ali Bazarbachi,Anna Sureda
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Research Article July 3 2025
Marstacimab Prophylaxis in Hemophilia A/B Without Inhibitors: Results from the Phase 3 BASIS Trial
Davide Matino,Andrew Palladino,Carrie Turich Taylor,Eunhee Hwang,Sangeeta Raje,Satyaprakash Nayak,Regina McDonald,Suchitra Acharya,Johnny Mahlangu,Victor Jiménez-Yuste,Nirmalkumar G Choraria, Dr.,Renchi Yang,Chi-kong Li,Murtadha Al-Khabori,Yasser Ahmed Mohamed Soliman Wali,Javier De Jesus Morales-Adrian,Young-Shil Park,Osman Bülent Zülfikar,John Teeter
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Review Article July 3 2025
Deciphering the dynamics of histone acetylation and chromatin remodeling in multiple myeloma: a tale beyond the tails
Sinan Xiong,Jianbiao Zhou,Wee Joo Chng
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Research Article July 3 2025
Restoring p53 wild-type conformation in TP53-Y220C-mutant acute myeloid leukemia
Bing Z Carter,Po Yee Mak,Edward Ayoub,Xiaogang Wu,Baozhen Ke,Yuki Nishida,Andrew Futreal,Lauren B Ostermann,Andrea D Bedoy,Steffen Boettcher,Courtney D. DiNardo,Anna Puzio-Kuter,Masha V Poyurovsky,Arnold J. Levine,Michael Andreeff
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Research Article June 26 2025
Association of Epstein-Barr virus genomic alterations with human pathologies
Htet Thiri Khine,Yoshitaka Sato,Motoharu Hamada,Miki Umeda,Akira Iizuka,Shika Son,Haruto Arai,Yuki Kojima,Takahiro Watanabe,Azumi Naruse,Kimitoshi Goto,Koichi Ohshima,Yuta Akutsu,Masato Nakaguro,Akira Satou,Hiromi Kataoka,Yoshinori Ito,Akihisa Sawada,Seiichi Kato,Jun-ichi Kawada,Takayuki Murata,Yusuke Okuno,Hiroshi Kimura
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Brief Report June 25 2025
Clinical and molecular features of immunodeficiency in patients with telomere biology disorders
Luiz Fernando B. Catto,Nidhi Aggarwal,Ruba N Shalhoub,Xiaoyang Ma,Ivana Darden,Tania Machado,Yue Zhang,Neelam Redekar,Natthakan Thongon,Simona Colla,Geraldine Aubert,Cynthia E. Dunbar,Colin O. Wu,Neal S. Young,Bhavisha A. Patel,Fernanda Gutierrez-Rodrigues,Emma M Groarke
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Review Article June 25 2025
Inflammatory Memory of Stem Cells: Implications for Hematological Diseases
Dongchang Zhao,Pavan Reddy
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Research Article June 25 2025
Clinical significance of preleukemic somatic GATA1 mutations in children with Down syndrome
Natalina Elliott,Neha Bhatnagar,Gemma Buck,David Cruz Hernandez,Kelly Perkins,Adam J. de Smith,Amélie Chaussade,Nizery Laure,Marlen Metzner,Garnett Catherine,Alice Norton,Kennedy Alison,Triya Chakravorty,Dylan Zhao,Lars Hanssen,Georgina W. Hall,Paresh Vyas,Irene Roberts
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Research Article June 25 2025
Posttranscriptional depletion of ribosome biogenesis factors engenders therapeutic vulnerabilities in NPM1-mutant AML
Aristi Damaskou,Rachael Wilson,Malgorzata Gozdecka,George Giotopoulos,Ryan Asby,Maria Eleftheriou,Muxin Gu,Christian Récher,Véronique Mansat- De Mas,Francois Vergez,Ambrine Sahal,Binje Vick,Evangelia K Papachristou,Ashley Sawle,Eliza Yankova,Monika Dudek,Xiaoxuan Liu,James Russell,Justyna Rak,Christine Hilcenko,Clive S D'Santos,Irmela Jeremias,Jean-Emmanuel Sarry,Konstantinos Tzelepis,Brian JP Huntly,Alan J Warren,Omid Tavana,George S Vassiliou
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Research Article June 25 2025
Deciphering opsonized zymosan-induced phosphorylation of p47phox and NADPH oxidase activation in human neutrophils
Jie Liu,Coralie Pintard,Nathalie Thieblemont,Pham My-Chan Dang,Jamel El Benna
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Research Article June 25 2025
IPSS-M risk and specific sex-associated somatic mutations predict response to ESA therapy in LR-MDS: building a new score
Marco Gabriele Raddi,Sophie Park,Michaela Fontenay,Olivier Kosmider,María Díez-Campelo,Juan Carlos Caballero Berrocal,Marie Sébert,Lionel Adès,Uwe Platzbecker,Matteo G Della Porta,Giorgio Mattiuz,Sven Julien Maria De Pourcq,Lorenzo Tofani,Giulia Maggioni,Elena Tofacchi,Angela Consagra,Luca Rigodanza,Gloria Andreossi,Cristina Amato,Mathieu Meunier,Célia Orlando,Emmanuelle Clappier,Nicolas Chapuis,Pierre Walczak,Katharina Zoldan,Anne Sophie Kubasch,Valeria Santini
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Research Article June 25 2025
The endothelial mTORC2-Foxo1 axis serves as an iron-responsive sensor governing systemic iron homeostasis
Wenting Zhao,Peina Wang,Zhengxun Liu,Dongyuan Zhang,Yi Xia,Teng Xu,Fei Wang,Mingyang Cui,Xu Zhang,Shuaishuai Zhou,Zhixi Wei,Min Ma,Sitong Wan,Jingyi Qi,Zhengyang Zhang,Juan Chen,Libing Liu,Yinhua Zhu,Junjie Luo,Yongting Luo,Peng An
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Research Article June 25 2025
Transposable elements as novel therapeutic targets for PARPi-induced synthetic lethality in PcG-mutated blood cancer
Bernd Zeisig,Chiou-Tsun Tsai,Clemence Virely,Tsz Kan Kan Fung,Ali Tugrul Akin,Estelle Troadec,Bo Jiao,Richard Thompson,Priscilla Nga Ieng Lau,Nanjun Li,Andriani Charalambous,Larissa Bomfim,Jennifer Lynch,Athina Georgiou,Robbert Hoogeboom,Claire Lynn,Si Yi Zhang,Piers EM Patten,Cynthia Fisher,Anna Schuh,Seishi Ogawa,Ghulam J Mufti, Professor,Mohammad M. Karimi,Chi Wai Eric So
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Research Article June 25 2025
Plasminogen as a Ribonucleoprotein: Regulatory small RNA Cargo Modulates Fibrinolysis and Inflammation
Danielle L Michell,Clark Massick,Kaustubh S Koya,Ashley B Cavnar,Elizabeth M Semler,Chase Raby,Breanne H Y Gibson,Stephanie N Moore-Lotridge,Wanying Zhu,Marisol Ramirez-Solano,Quanhu Sheng,Ryan M Allen,MacRae F Linton,Jonathan G Schoenecker,Kasey Vickers
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Research Article June 20 2025
Loss of BAP1 defines a unique subtype of TP53-mutated de novo AML and confers sensitivity to BCL-xL inhibitors
Jaclyn Andricovich,Coen Johannes Lap,Alexandros Tzatsos
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Research Article June 20 2025
LRRC8 complexes are ATP release channels regulating platelet activation and arterial thrombosis
John David Tranter,Ryan Takayuki Mikami,Ashutosh Kumar,Gavriel Brown,Tarek Mohamed Abd El-Aziz,Yonghui Zhao,Prakash Arullampalam,Katrina J Ashworth,Vishwanath Jha,Nihil Abraham,Chloe Meyer,Abigail Ajanel Gomez,Litao Xie,Yongmei Feng,Juan Hong,Haixia Zhang,Tripti Kumari,Adam Balutowski,Alice Liu,David Bark,Vinayak K Nair,Nina M Lasky,Nathan O Stitziel,Daniel J Lerner,Robert A Campbell,Jorge Di Paola,Jaehyung Cho,Rajan Sah
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Research Article June 20 2025
Bone marrow neutrophil progenitors suppress osteoclast formation in murine cortical and trabecular bone
Tsuyoshi Isojima,Blessing Crimeen-Irwin,Narelle E McGregor,Ryan C Chai,Ingrid J Poulton,Emma C Walker,Mriga Dutt,Benjamin L Parker,Natalie A Sims
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Research Article June 20 2025
Somatic IRF4 Mutations and Thymic Tropism in Primary Mediastinal Large B-cell Lymphoma
Shinya Rai,Gerben Duns,Fabian Frontzek,Jasper Chun Hei Wong,Yifan Yin,Michael Y. Li,Makoto Kishida,Manabu Fujisawa,Shannon Healy,Elena Viganò,Aixiang Jiang,Bruce Woolcock,Adèle Telenius,Susana Ben-Neriah,Barbara Meissner,Merrill Boyle,Hisae Nakamura,Luke O`Brien,Claudia Cassidy,Andrew Lytle,Pedro Farinha,Graham W. Slack,Laura K Hilton,Ryan D Morin,Leandro Venturutti,Tomohiro Aoki,Nicole Wretham,Jonathan Willard Bush,Laura Evgin,Kerry J. Savage,David W. Scott,Christian Steidl
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Research Article June 13 2025
TNFα signaling restores steady-state hematopoiesis in a TNFαKO mouse model of anemia of inflammation
Amaliris Guerra,Vania Lo Presti,Ding-Wen Chen,Ana C. Martins,Ariel Rivera,Nolan Hamilton,Pankaj Sharma,Yelena Z Ginzburg,Carlo Castruccio Castracani,Carla Casu,Ritama Gupta,Raffaella Gozzelino,Edward M Behrens,Laura Bennett,Robert F. Paulson,Peter Kurre,Stefano Rivella
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Research Article June 12 2025
A single dose of a CD137 antibody-drug conjugate protects nonhuman primate allogeneic HCT recipients against acute GVHD
Ulrike Gerdemann,Kyle Kimler,Matthew R Warren,Connor McGuckin,Ryan A Fleming,Matthew R D'Ambra,Alal Eran,Alexandre Albanese,Edward Chen,Marlana B Winschel,Lorenzo Cagnin,Jennifer Lane,Lev Gorfinkel,Bartley W. Adams,Jean Kwun,Leanne Lanieri,Megan D Hoban,Tahirih L Lamothe,Sharon L. Hyzy,Lisa M. Olson,Angela Panoskaltsis-Mortari,Susan E Prockop,Bruce R Blazar,Leslie S Kean,Victor Tkachev
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Research Article June 12 2025
RhoA GAP Myo9b regulates β2-integrin activity and neutrophil recruitment during murine acute kidney injury
Anika Cappenberg,Marina Oguama,Mathis Richter,Andreas Margraf,Wida Amini,Pia Lindental,Sina Mersmann,Bernadette Bardel,Helena Block,Thomas Vogl,Oliver Soehnlein,Klaus Ley,Jan Rossaint,Alexander Zarbock
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Research Article June 12 2025
Remission conversion drives outcomes after CAR T-cell therapy for multiple myeloma: a registry analysis from the DRST
Maximilian Merz,Nico Gagelmann,Samih Smaili,Sarah Flossdorf,Sandra Sauer,Christof Scheid,Bastian von Tresckow,Gerald Georg Wulf,Katja C Weisel,Igor Blau,Monika Engelhardt,Ralph Wäsch,Natalie Schub,Raphael Teipel,Judith S. Hecker,Johannes M. Waldschmidt,Britta Besemer,Ben-Niklas Baermann,Simon Call,Leo Hansmann,Francis Ayuketang Ayuk,Marc S. Raab,Hermann Einsele,Uwe Platzbecker,Nicolaus Kröger
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Brief Report June 12 2025
Comparison of the safety profiles of CD19-targeting CAR T-cell therapy in patients with SLE and B-cell lymphoma
Fabian Müller,Nora Rebecca Schwingen,Melanie Hagen,Julia Katharina Scholz,Michael Aigner,Andreas Wirsching,Jule Taubmann,Sascha Kretschmann,Soraya Kharboutli,Tobias Krickau,Nora Naumann-Bartsch,Giulia Benintende,Silvia Spoerl,Tobias Rothe,Heiko Bruns,Ricardo Grieshaber-Bouyer,Markus Metzler,David B. Blumenthal,Frederik Graw,Georg Schett,Andreas Mackensen,Simon Völkl
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Research Article June 11 2025
Combined PET and ctDNA response as a predictor of POD24 for follicular lymphoma after first-line induction treatment
Alexis Claudel,Anne-Ségolène Cottereau,Emmanuel Bachy,Emmanuel Itti,Pierre Feugier,Cédric Rossi,Francois Lemonnier,Vincent Camus,Nicolas Daguindau,Guillaume Cartron,Emmanuelle Nicolas Virelizier,Diana Laure Mbouma,Christophe Cardoso,Côme Bommier,Benoit Tessoulin,Christophe Fruchart,Adrien Gilbert,Eric Durot,Emmanuel Fleck,Gian Matteo Pica,Hacene Zerazhi,Stéphanie Guidez,Morgane Cheminant,Clémentine Sarkozy,Luc Xerri,Laetitia Vercellino,Nesrine Trabelsi,Lucie Gomes,Cedric Portugues,Pierre-Julien Viailly,Marie-Helene Delfau-Larue,Franck Morschhauser
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Research Article June 11 2025
Array Genotyping of Transfusion Relevant Blood Cell Antigens in 6946 Ancestrally Diverse Subjects
Nicholas S Gleadall,Lianne Koets,Olga Shamardina,Jeremy Gollub,Aaron J Gottschalk,Orod Razeghi,Gorka Ochoa,Jonathan Stephens,Ram Varma,Jennifer Martin,Elias Allara,Colin J Brown,James Daly,Emanuele Di Angelantonio,Shane Grimsley,W Martin Howell,Kati Hyvärinen,Ute Jentsch,Nathalie Kingston,Celina Montemayor,Celeste Moya-Valera,John Ord,Jukka Partanen,David J Roberts,Kathleen E. Stirrups,Sunitha Vege,Lindsay Walker,Andrea Harmer,Shantanu Kaushikkar,Willem H Ouwehand,C Ellen van der Schoot,Connie M Westhoff,Barbera Veldhuisen,William J Lane
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Research Article June 11 2025
High-dose busulfan-melphalan vs melphalan and reinforced VRD for newly diagnosed multiple myeloma: a phase 3 GEM trial
Juan-Jose Lahuerta,Jesús F. San-Miguel,Ana Jiménez-Ubieto,Rafael Alonso Fernández,Bruno Paiva,Noemi Puig,Maria-Teresa Cedena,Norma C Gutierrez,Maria José Calasanz,Manuela Fernandez,Rafael Ríos-Tamayo,Albert Oriol,María-Jesús Blanchard,Estrella Carrillo-Cruz,Rafael Martínez-Martínez,Joan Bargay,Anna Sureda,Javier de la Rubia,Miguel-Teodoro T. Hernandez Garcia,Valentín Cabañas,Luis Felipe Casado Montero,Luis Palomera Bernal,Yolanda Gonzalez-Montes,Joaquín Martínez-López,Paula Rodriguez-Otero,Isabel Krsnik,Jose M Arguiñano,María Esther Gonzalez-Garcia,Enrique M. Ocio,Javier de la Cruz,Maria-Victoria Mateos,Laura Rosiñol,Joan Bladé
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Research Article June 11 2025
Correlates and Consequences of Clonal Hematopoiesis Expansion Rate: A 16-Year Longitudinal Study of 6976 Women
Yash Pershad,Md Mesbah Uddin,Liying Xue,Jeffrey Haessler,Jason M Collins,Taralynn Mack,Elena Glick,Veronica Glaser,Kun Zhao,Siddhartha Jaiswal,JoAnn E Manson,Urvashi Pandey,Pinkal Desai,Pradeep Natarajan,Michael C. Honigberg,Charles Kooperberg,Eric A Whitsel,Jacob Kitzman,Alexander G. Bick,Alex P Reiner
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Research Article June 10 2025
Single-cell and clonal analysis of AL amyloidosis plasma cells and their bone marrow microenvironment
Nicolas A. Gort-Freitas,Maria Moscvin,Matteo Claudio Da Viá,Francesca Lazzaroni,Alice Nevone,Sam Sadigh,Samuel Boullt,Benjamin Evans,Tianzeng Chen,Tanya T Karagiannis,Albert Tai,Sean Rowell,Srinidhi Raghav,Antonia Faustina Chen,Jacob P Laubach,Caitlin Edwards,Jon C Aster,Zizhang Sheng,Joao A Paulo,Chi N Chan,Mario Nuvolone,Niccolò Bolli,Raymond L. Comenzo,Allon Klein,Giada Bianchi
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Research Article June 10 2025
An in vivo barcoded CRISPR-Cas9 screen identifies Ncoa4-mediated ferritinophagy as a dependence in Tet2-deficient hematopoiesis
Justin Loke,Peter Geon Kim,Thuy T.P. Nguyen,Meaghan Boileau,Marie McConkey,Aidan P Miller,Wesley Shin,Christopher B Hergott,Maria Ericsson,Anja Nordstrom,Paula Montero-Llopis,Scott A. Armstrong,Joseph D. Mancias,Benjamin L Ebert
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Research Article June 10 2025
Biallelic antigen escape is a mechanism of resistance to anti-CD38 antibodies in multiple myeloma.
Benjamin T. Diamond,Linda B Baughn,Mansour Poorebrahim,Alexandra M Poos,Holly Lee,Marcella Kaddoura,J Erin Wiedmeier-Nutor,Michael A. Durante,Gregory E Otteson,Dragan Jevremovic,Hongwei Tang,Stefan Fröhling,Marc-Andrea Baertsch,Marios Papadimitriou,Bachisio Ziccheddu,Tomas Jelínek,Cendrine Lemoine,Alexey Rak,Damian J Green,Carl Ola Landgren,Paola Neri,Peter Leif Bergsagel,Esteban Braggio,Shaji K Kumar,Marc S. Raab,Rafael Fonseca,Nizar Bahlis,Niels Weinhold,Francesco Maura
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Research Article June 10 2025
The T follicular helper/T follicular helper regulatory pathway in FVIII immune responses in mice
Weiqing Jing,Jocelyn A Schroeder,Saurabh Kumar,Juan Chen,Yuanhua Cai,Lynn M Malec,Alexander L. Dent,Weiguo Cui,Qizhen Shi
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Brief Report June 9 2025
Eliminating The Need for Sequential Confirmation of Response in Multiple Myeloma
Jean-Sébastien Claveau,Prashant Kapoor,Moritz Binder,Francis K Buadi,David Dingli,Angela Dispenzieri,Amie L Fonder,Morie A Gertz,Wilson I Gonsalves,Suzanne R Hayman,Miriam A Hobbs,Lisa Hwa Christenson,Taxiarchis V. Kourelis,Martha Q Lacy,Nelson Leung,Yi Lin,Rahma Warsame,Robert A Kyle,S. Vincent Rajkumar,Shaji K Kumar
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Discussion June 9 2025
Challenges in GVHD and GVL after hematopoietic stem cell transplantation for myeloid malignancies
Gérard Socié
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Discussion June 2 2025
Hitting the Therapeutic Bullseye with Targeted Therapy for Patients with Chronic Lymphocytic Leukemia
William G. Wierda,Barbara F. Eichhorst,Michael J Hallek
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Research Article June 2 2025
Reactivation of developmentally silenced globin genes through forced linear recruitment of remote enhancers
Anna-Karina Felder,Sjoerd J.D. Tjalsma,Han J.M.P. Verhagen,Rezin Majied,Marjon J.A.M. Verstegen,Thijs C.J. Verheul,Jeffrey van Haren,Rebecca Mohnani,Richard Gremmen,Peter H.L. Krijger,Sjaak Philipsen,Emile van den Akker,Wouter de Laat
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Research Article May 30 2025
Phase 1/2 Trial of Anti-CD7 Allogeneic WU-CART-007 in patients with Relapsed/Refractory T-cell Malignancies
Armin Ghobadi,Ibrahim Aldoss,Shannon L. Maude,Deepa Bhojwani,Alan S. Wayne,Ashish Bajel,Bhagirathbhai Dholaria,Rawan G. Faramand,Ryan J Mattison,Anita W Rijneveld,C. Michel Zwaan,Friso G. Calkoen,André Baruchel,Nicolas Boissel,Michael P Rettig,Brent Wood,Kenneth Jacobs,Stephanie Christ,Haley Irons,Ben Capoccia,Deborah Masters,Justo Gonzalez,Tony Wu,Maria del Rosario,Alexander Hamil,Ouiam Bakkacha,John Muth,Brett Ramsey,Eileen McNulty,Jan Baughman,Matthew L Cooper,Jan K Davidson-Moncada,John F. DiPersio
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Research Article May 28 2025
Differentiation-dependent EBF1 Activity Determines CD22 Transcription and Leukemia Sensitivity to Inotuzumab Ozogamicin
Carolin S. Escherich,Zhenhua Li,Kelly R Barnett,Yizhen Li,Megan Walker,Satoshi Yoshimura,Wenjian Yang,Xin Huang,Jiyang Yu,Wendy Stock,Elisabeth Paietta,Marina Y. Konopleva,Steven M Kornblau,Elias Jabbour,Mark R Litzow,Hiroto Inaba,Ching-Hon Pui,Mignon L. Loh,William E. Evans,Daniel Savic,Jun J Yang
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Research Article May 28 2025
RBM15-MKL1 fusion protein promotes leukemia via m6A methylation and WNT pathway activation
Madeline Y Mayday,Giulia Biancon,Manyi Wei,Christian Ramirez,Irene Moratti,Andreas P Pintado-Urbanc,Jether Amos Espinosa,Mi Chen,Lin Wang,Matthew D Simon,Yaara Ofir-Rosenfeld,Oliver Rausch,Toma Tebaldi,Stephanie Halene,Diane S Krause
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Research Article May 28 2025
PERK Maintains Hematopoietic Stem Cell Pool Integrity under Endoplasmic Reticulum Stress by Promoting Proliferation
Manxi Zheng,Qinlu Peng,Erin M Kropp,Zhejuan Shen,Suxuan Liu,Zhengyou Yin,Sho Matono,Takao Iwawaki,Xiang Wang,Ken Inoki,Yang Mei,Qing Li,Lu Liu
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Research Article May 22 2025
Sequential combinations of rapid immunoassays for prompt recognition of heparin-induced thrombocytopenia
Thomas Steinauer,Elena Matthey-Guirao,Francisco Javier Gomez,Luana Rittener-Ruf,Matteo Marchetti,Matthew Goodyer,Mitja Nabergoj,Stefano Barelli,Francesco Grandoni,Maxime Grégoire Zermatten,Lorenzo Alberio
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Research Article May 22 2025
Imaging Mass Cytometry Reveals the Order of Events in the Pathogenesis of Immune-Mediated Aplastic Anemia
Emma S. Pool,Sietse J. Luk,Marieke E. IJsselsteijn,Vincent van Unen,Noel F.C.C. de Miranda,J.H. Frederik Falkenburg,Frits Koning,Mirjam H.M. Heemskerk,Jennifer M-L. Tjon
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