First Edition
Research Article
January 24 2020
The complement C5 inhibitor crovalimab in paroxysmal nocturnal hemoglobinuria
Alexander Röth,Jun-ichi Nishimura,Zsolt Nagy,Julia Gaal-Weisinger,Jens Peter Panse,Sung-Soo Yoon,Miklos Egyed,Satoshi Ichikawa,Yoshikazu Ito,Jin Seok Kim,Haruhiko Ninomiya,Hubert Schrezenmeier,Simona Sica,Kensuke Usuki,Flore Sicre de Fontbrune,Juliette Soret-Dulphy,Alexandre Sostelly,James Higginson,Andreas Dieckmann,Brittany Gentile,Judith Anzures-Cabrera,Kenji Shinomiya,Gregor Jordan,Marta Biedzka-Sarek,Barbara Klughammer,Angelika Jahreis,Christoph Bucher,Régis Peffault de Latour
Brief Report
January 24 2020
MPL Mutations in Essential Thrombocythemia Uncover A Common Path of Activation with Eltrombopag Dependent on W491
Research Article
January 24 2020
High total metabolic tumor volume at baseline allows discrimination of survival even in patients aged 60 to 80 years responding to R-CHOP
Laetitia Vercellino,Anne-Ségolène Cottereau,Rene-Olivier Casasnovas,Herve Tilly,Pierre Feugier,Loic Chartier,C. Fruchart,Louise Roulin,Lucie Obéric,Gian Matteo Pica,Vincent Ribrag,Julie Abraham,Marc Simon,Hugo Gonzalez,Reda Bouabdallah,Olivier Fitoussi,Catherine j Sebban,Armando López-Guillermo,Laurence Sanhes,Franck Morschhauser,Judith Trotman,Bernadette Corront,Bachra Choufi,Sylvia Snauwaert,Pascal Godmer,Josette Briere,Gilles Andre Salles,Philippe Gaulard,Michel Meignan,Catherine Thieblemont
Research Article
January 24 2020
How I Treat Obese Patients with Oral Anticoagulants
Research Article
January 23 2020
Assessment of ST2 for risk of death following graft-versus-host disease in the pediatric and adult age groups
Research Article
January 23 2020
Feed-forward Regulatory Loop Driven by IRF4 and NF-κB in Adult T-cell Leukemia/Lymphoma
Letter
January 23 2020
Outcomes of rare patients with a primary cutaneous CD30+ lymphoproliferative disorder developing extracutaneous disease
Letter
January 23 2020
Co-occurrence of DNMT3A, NPM1, FLT3 mutations identifies a subset of acute myeloid leukemia with adverse prognosis
Matheus F Bezerra,Aleide Santos Lima,Maria-Riera Piqué-Borràs,Douglas RA Silveira,Juan Luiz Coelho-Silva,Diego A Pereira-Martins,Isabel Weinhäuser,Pedro Luiz Franca Neto,Lynn Quek,Anna Corby,Mayara Matias Oliveira,Marinus Lima,Reijane Alves de Assis,Paula De Melo Campos,Bruno Kosa Lino Duarte,Israel Bendit,Vanderson Rocha,Eduardo M. Rego,Fabiola Traina,Sara Olalla Saad,Eduardo Beltrao,Marcos Bezerra,Antonio R. Lucena-Araujo
Research Article
January 23 2020
Avadomide monotherapy in relapsed/refractory DLBCL: Safety, efficacy, and a predictive gene classifier
Cecilia Carpio,Reda Bouabdallah,Loïc Ysebaert,Juan-Manuel Sancho,Gilles Andre Salles,Raul Cordoba,Antonio Pinto,Mecide Gharibo,Drew Rasco,Carlos Panizo,Jose A Lopez-Martin,Armando Santoro,Antonio Salar,Silvia Damian,Alejandro Martin Garcia-Sancho,Gregor Verhoef,Eric W Van Den Neste,Maria Wang,Suzana Couto,Soraya Carrancio,Andrew Weng,Xuehai Wang,Frank Schmitz,Xin Wei,Kristen M Hege,Matthew William Burnell Trotter,Alberto Risueno,Tonia Buchholz,Patrick Ryan Hagner,Anita Krithivas Gandhi,Michael Pourdehnad,Vincent Ribrag
Research Article
January 23 2020
Leveraging Gene Expression Subgroups to Classify DLBCL Patients and Enrich for Clinical Benefit to a Novel Agent
Research Article
January 23 2020
How I Treat the Toxicities of Pegasparaginase in Adults with Acute Lymphoblastic Leukemia
Research Article
January 23 2020
Protein C activator AB002 rapidly interrupts thrombus development in baboons and appears safe in a first-in-human trial
Research Article
January 22 2020
Subclonal NT5C2 mutations are associated with poor outcomes after relapse of pediatric acute lymphoblastic leukemia
Research Article
January 22 2020
Red Blood Cell Microvesicles Activate The Contact System Leading To Factor IX Activation Via Two Independent Pathways
Letter
January 21 2020
Long-term outcomes of Sleeping Beauty generated CD19specific CAR T-cell therapy for relapsed-refractory B-cell lymphomas
Samer Srour,Harjeet Singh,Jessica McCarty,Eleanor de Groot,Helen Huls,Gabriela Rondon,Muzaffar H Qazilbash,Stefan O. Ciurea,Geraldine Bardelli,Jill Buck,Amin Alousi,Yago Nieto,Katy Rezvani,David Marin,Uday Popat,Chitra Hosing,Elizabeth J Shpall,William George Wierda,Hagop Kantarjian,Richard Champlin,Laurence Cooper,Partow Kebriaei
Research Article
January 21 2020
Rare and private spliceosomal gene mutations drive partial, complete, and dual phenocopies of hotspot alterations
Research Article
January 21 2020
Progressive or Relapsed Burkitt Lymphoma or Leukemia in Children and Adolescents after BFM-type First-line Therapy
Research Article
January 17 2020
How I assess and manage the risk of bleeding during treatment of patients with venous thromboembolism
Letter
January 17 2020
Multiple BCL2 mutations co-occurring with Gly101Val emerge in chronic lymphocytic leukemia progression on venetoclax
Research Article
January 16 2020
Brentuximab vedotin with chemotherapy for Stage III/IV classical Hodgkin lymphoma: 3-year update of the ECHELON-1 study
David J. Straus,Monika Długosz-Danecka,Sergеу Alekseev,Arpad Illes,Marco Picardi,Ewa Lech-Maranda,Tatyana Feldman,Piotr Smolewski,Kerry J. Savage,Nancy L. Bartlett,Jan Walewski,Radhakrsihnan Ramchandren,Pier Luigi Zinzani,Martin Hutchings,Joseph M. Connors,John Radford,Javier Munoz,Won S Kim,Ranjana Advani,Stephen M. Ansell,Anas Younes,Harry Miao,Rachael Liu,Keenan Fenton,Andres Forero,Andrea Gallamini
Review Article
January 15 2020
Virus specific T-cell Therapies for Patients with Primary Immune Deficiency
Review Article
January 15 2020
Increased activation of PI3 kinase-δ predisposes to B cell lymphoma.
Research Article
January 14 2020
High-Parametric Evaluation of Human Invariant Natural Killer T Cells to Delineate Heterogeneity in Allo- and Autoimmunity
Research Article
January 13 2020
IGHV sequencing reveals acquired N-glycosylation sites as a clonal and stable event during follicular lymphoma evolution
Research Article
January 13 2020
Improved transplant survival and long-term disease outcome in children with MHC class II deficiency
Su Han Lum,Claire Anderson,Peter McNaughton,Karin Regine Engelhardt,Brigid MacKenzie,Helen Watson,Hamoud A Al-Mousa,Waleed Al Herz,Bandar Al-Saud,Reem Mohammed,Daifulah M Al-Zahrani, Assistant prof.,Hamza AlGhamdi,Loie Goronfolah,Zohreh Nademi,Sahar Habibollah,Aisling M Flinn,Benjamin Shillitoe,Stephen Owens,Eleri Williams,Marieke Emonts,Sophie Hambleton,Mario Abinun,Terence Flood,Andrew Cant,Andrew R Gennery,Mary Slatter
Research Article
January 13 2020
External Validation of Models for KIR2DS1/KIR3DL1-informed Selection of Hematopoietic Cell Donors fails
Johannes Schetelig,Henning Baldauf,Falk Heidenreich,Carolin Massalski,Sandra Frank,Jürgen Sauter,Matthias Stelljes,Francis Ayuk,Wolfgang Andreas Bethge,Gesine Bug,Stefan Klein,Sarah Wendler,Vinzenz Lange,Liesbeth C. de Wreede,Daniel Fuerst,Guido Kobbe,Hellmut D Ottinger,Dietrich W. Beelen,Joannis Mytilineos,Katharina Fleischhauer,Alexander H Schmidt,Martin Bornhauser
Research Article
January 13 2020
Molecular MRD status and outcome after transplantation in NPM1 mutated AML: results from the UK NCRI AML17 study
Richard Dillon,Robert K Hills,Sylvie D Freeman,Nicola Potter,Jelena Jovanovic,Adam Ivey,Anju Shankar Kanda,Manohursingh Runglall,Nicola Foot,Mikel Valganon,Asim Khwaja,Jamie Cavenagh,Matthew L Smith,Hans Beier Ommen,Ulrik Overgaard,Mike Dennis,Steven Knapper,Harpreet Kaur,David C Taussig,Priyanka Mehta,Kavita Raj,Igor Novitzky-Basso,Emmanouil Nikolousis,Robert D Danby,Pramila Krishnamurthy,Kate Hill,Damian Finnegan,Samah Alimam,Erin Hurst,Peter Johnson,Anjum Bashir Khan,Rahuman Salim,Charles F Craddock,Ruth Lilian Spearing, Dr,Amanda Frances Gilkes,Rosemary E Gale,Alan Kenneth Burnett, -,Nigel H. Russell,David Grimwade
Research Article
January 13 2020
Dnmt3a loss and Idh2 neomorphic mutations mutually potentiate malignant hematopoiesis
Letter
January 13 2020
Prevalence and disease predisposition of p.A91V perforin in an aged Caucasian population
Research Article
January 13 2020
Molecular patterns of response and treatment failure after frontline venetoclax combinations in older patients with AML
Courtney D. DiNardo,Ing Soo Tiong,Anna Quaglieri,Sarah MacRaild,Sanam Loghavi,Fiona C Brown,Rachel Thijssen,Giovanna Pomilio,Adam Ivey,Jessica Salmon,Christina Glytsou,Shaun Alan Fleming,Qi Zhang,Helen Ma,Keyur P Patel,Steven M Kornblau,Zhen Xu,Chong Chyn Chua,X Chen,Piers Blombery,Christoffer Flensburg,Nik Cummings,Iannis Aifantis,Hagop Kantarjian,David Ching Siang Huang, Professor,Andrew W. Roberts,Ian J Majewski,Marina Konopleva,Andrew H Wei
Research Article
January 13 2020
Complement blockade for TA-TMA: lessons learned from large pediatric cohort treated with eculizumab
Review Article
January 9 2020
Managing Thromboembolic Risk in Patients with Hereditary and Acquired Thrombophilias
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