Human cyclic neutropenia shows many features in common with the animal model of cyclic neutropenia in grey collie dogs. Until now, however, evidence was lacking that cyclic neutropenia in man as in the dog is caused by a defect in a transplantable hematopoietic stem cell. A patient is presented who, while undergoing bone marrow transplantation as treatment for acute lymphoblastic leukemia in relapse, acquired cyclic neutropenia from her histocompatible sibling donor.
Human cyclic neutropenia transferred by allogeneic bone marrow grafting
- Share Icon Share
- Tools Icon Tools
- Search Site
- PDF LinkPDF
RA Krance, WE Spruce, SJ Forman, RB Rosen, T Hecht, WP Hammond, KG Blume; Human cyclic neutropenia transferred by allogeneic bone marrow grafting. Blood 1982; 60 (6): 1263–1266. doi: https://doi.org/10.1182/blood.V60.6.1263.bloodjournal6061263
Download citation file: