Blood smears of 27 cases of hemolytic disease of the newborn were studied intensively for erythrophagocytes. In 25 cases, the smears were positive for this phenomenon.
In a control series of 30 normal newborn infants, these cells were not found.
Prolonged search and optimum magnification of the smears were important factors in determining the presence or absence of erythrophagocytes in the cases under study.
ACKNOWLEDGMENTS For help and interest in this study, grateful acknowledgment is made to the late Dr. William A. Groat, to Dr. Tyree C. Wyatt, to Dr. Eugene L. Lozner and to the pediatric services of Crouse-Irving Hospital, Syracuse Memorial Hospital and The General Hospital of Syracuse. Special thanks are given to Viola Grant for technical assistance and to Stella Zimmer for the photomicrographs.