RICHARD M. ANGLE, HOWARD L. ALT; THROMBOCYTOPENIC PURPURA COMPLICATING INFECTIOUS MONONUCLEOSIS : REPORT OF A CASE AND SERIAL PLATELET COUNTS DURING THE COURSE OF INFECTIOUS MONONUCLEOSIS. Blood 1950; 5 (5): 449–457. doi: https://doi.org/10.1182/blood.V5.5.449.449
A case has been presented in which thrombocytopenic purpura was a complication of infectious mononucleosis. A review of the literature revealed 6 other cases in which there was an association between these conditions. Serial platelet counts were made in 7 consecutive cases of infectious mononucleosis. There was a slight depression of the platelets early in the illness, followed by a thrombocytosis and a subsequent return to normal. Hypersplenism is considered as a possible cause for the thrombocytopenia in infectious mononucleosis.