MURRAY WEINER, SHEPARD SHAPIRO; INFLUENCE OF FIBRINOGEN CONCENTRATION UPON PLASMA PROTHROMBIN TIME. Blood 1949; 4 (8): 977–981. doi: https://doi.org/10.1182/blood.V4.8.977.977
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The effect of the normal variations of fibrinogen concentration (180 mg. per cent to 650 mg. per cent) on the diluted (12.5 per cent) plasma prothrombin time in man, as observed in this study, is not significant.
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