OBSERVATIONS ON THE EFFECT OF AN ANIMAL PROTEIN FACTOR CONCENTRATE ON PERSONS WITH THE MACROCYTIC ANEMIA OF PERNICIOUS ANEMIA, OF NUTRITIONAL MACROCYTIC ANEMIA AND OF SPRUE, AND ON PERSONS WITH NUTRITIONAL GLOSSITIS

The intramuscular injection of animal protein factor concentrate to 5 cases of pernicious anemia in relapse, 4 cases of nutritional macrocytic anemia in relapse, and 3 cases of tropical sprue in relapse was followed by a positive hematologic response in each case as is illustrated in figures 1, 2, and 4, respectively. The parenteral administration of this material to 3 patients with nutritional glossitis unassociated with anemia was followed by the disappearance of the redness and soreness of the tongue.