Highly satisfactory results obtained with 50 mg./week nandrolone decanoate (Deca-Durabolin) for 3-16 months are reported in 10 cases of aplastic anemia. In the series thus treated there were only two deaths, occurring after only a few months of treatment. All other cases benefited to a large degree: in six, normalization was achieved, and a distinct improvement was seen in two still under treatment. Once therapy had been commenced, there was a period of latency which fluctuated between 1 and 9 months. Except for one patient with Fanconi’s anemia, the other normalized cases have not relapsed after suspension of the drug.