Abstract

The literature pertaining to the association of chronic leg ulcer with diseases of the blood other than sickle cell anemia has been reviewed.

Two patients with this association have been presented. One patient had a hemolytic anemia and the other a pancytopenia (secondary hypersplenism) in association with congestive splenomegaly due to cirrhosis of the liver.

It is suggested that the association of leg ulcer with these various diseases of the blood is related in an unknown manner to either splenomegaly or hyperfunction of the spleen (hypersplenism).

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