1. A case of myelomatosis with "a2-type" myeloma protein in the serum is described.
2. Previously reported cases of myelomatosis with this rare type of serum protein pattern have been reviewed.
3. It is concluded from the limited data available that the clinical features of cases with the "a2-type" serum protein pattern and the prognosis are, in general, not different from those of patients with other protein abnormalities.