It has been shown that red cells sensitized with anti-Rh antibody are agglutinated by anti-γ-globulin sera, regardless of the "order" of Rh antibody activity. Red cells sensitized with anti-Lewis antibody, on the other hand, are agglutinated by anti-sera to non-γ-globulin substances. Of six other blood group antibodies studied, five provided γ-globulin red cell coating materials and one, an anti-Kidd, a non-γ-globulin material. The participation of complement, or complement-like, substances was shown in some instances.
Various pitfalls in the technics employed in absorbing Coombs sera so as to render them immunochemically specific are discussed.
This content is only available as a PDF.
© 1957 by American Society of Hematology, Inc.
This feature is available to Subscribers OnlySign In or Create an Account Close Modal