Therapeutic options for patients (pts) with relapsed/refractory B-NHL and poor bone marrow reserve are limited. Denileukin diftitox (DD), a recombinant fusion protein, which when given at the standard dose, is not myelosuppressive and achieved a response rate of 25% in pts with relapsed/refractory B-NHL (
Disclosures: The study of ONTAK in the treatment of B-cell lymphoma patients with limited bone marrow reserve.; Mark Acosta employed at Ligand Pharmaceuticals.; Mark Acosta has stock options but currently does not own any stock.; M. Czuczman: Clinical research funding.; Lauren Pinter-Brown has spoken/presented on behalf of Ligand.