Abstract
The cell cycle inhibitor FL targets cyclin-dependent kinases, induces checkpoint arrest and interrupts transcriptional elongation. We demonstrated in an in vitro model that F causes apoptosis in leukemic blasts and increases A cytotoxicity in remaining blasts (
Clin Cancer Res
9
: 307
–315, 2003
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Corresponding author
2005, The American Society of Hematology
2005