A new type of abnormal fetal hemoglobin, identified in Rome from the cord blood hemolysate of a healthy newborn girl, is described. This abnormal hemoglobin, which the authors provisionally name Hb FRoma, has an electrophoretic mobility at alkaline pH identical to that of Hb Bart’s and a spectrum in the U. V. of the fetal type. It is, however, composed of normal alpha chains and altered gamma chains. Hb FRoma, which was present at birth in the portion of 17 per cent, disappeared completely during the 5th month of life. No abnormal hemoglobins were identified in the parents.

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© 1963 by American Society of Hematology, Inc.
1963

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