A severe form of hypersensitivity to para-aminosalicylic acid in patients with tuberculosis was studied. The blood picture, lymph node biopsies, and imprints are described. The similarities between this hypersensitivity to a simple chemical and infectious mononucleosis and infectious hepatitis are discussed. The possibility is suggested that some of the findings in viral diseases are due to hypersensitivity to chemical substances derived from the virus rather than to infection per se.

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