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October 28, 2020
A remarkable case of HbH disease illustrates the relative contributions of the α-globin enhancers to gene expression
Mohsin Badat,
Mohsin Badat
MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, United Kingdom
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James Davies,
James Davies
University of Oxford, Oxford, United Kingdom
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Christopher Fisher,
Christopher Fisher
MRC Weatherall Institute for Molecular Medicine, University of Oxford, Oxford, United Kingdom
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Damien J Downes,
Damien J Downes
MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, United Kingdom
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Anna Rose,
Anna Rose
Oxford University, Oxford, United Kingdom
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Andreas Glenthøj,
Andreas Glenthøj
Rigshospitalet, Copenhagen, Denmark
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Eduard J van Beers,
Eduard J van Beers
University Medical Center Utrecht, Utrecht, Netherlands
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Cornelis L. Harteveld,
Cornelis L. Harteveld
Leiden University Medical Center, Leiden, Netherlands
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Douglas R Higgs
MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, United Kingdom
* Corresponding Author; email: doug.higgs@imm.ox.ac.uk
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Blood blood.2020006680.
Article history
Submitted:
May 15, 2020
Revision Received:
September 28, 2020
Accepted:
October 2, 2020
Citation
Mohsin Badat, James Davies, Christopher Fisher, Damien J Downes, Anna Rose, Andreas Glenthøj, Eduard J van Beers, Cornelis L. Harteveld, Douglas R Higgs; A remarkable case of HbH disease illustrates the relative contributions of the α-globin enhancers to gene expression. Blood 2020; blood.2020006680. doi: https://doi.org/10.1182/blood.2020006680
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