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Issue Highlights
- XIAP deficiency is associated with defective autophagy and IL-1–mediated inflammation
- Phase 1 study of CAR-37 T cells for R/R lymphoid malignancy
- T-cell states influence outcomes of patients with AML
- ATM variants affect outcomes in children with ataxia-telangiectasia and hematologic malignancy
- Preclinical study of a novel menin-KMT2A inhibitor in KMT2A- and NPM1-mutant leukemias
- Molecular and clinical presentation of UBA1-mutated MDS
- Special Report: 100 years of progress and treatment for TTP
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