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Clotting Disorders

December 20, 2021

A collection of features and news articles published in ASH Clinical News related to clotting disorders.


Site of Cancer Could Predict VTE Recurrence After Anticoagulation Cessation

Despite having active cancer, patients who have surgery-associated venous thromboembolism (VTE) may only require time-limited anticoagulation ...

Recombinant ADAMTS13 Yielded Higher ADAMTS13 Exposure Compared With Plasma Exchange for iTTP

Recombinant ADAMTS13 (rADAMTS13) plus plasma exchange increased ADAMTS13 exposure in patients with immune-​mediated thrombotic thrombocytopenic purpura (iTTP) compared with placebo plus plasma exchange ...

Efgartigimod Shows Long-Term Safety, Efficacy in Long-Standing Primary ITP

An interim analysis of the open-label extension ADVANCE+ study suggests that long-term efgartigimod has an acceptable side effect profile and is not associated with increased exposure-adjusted risk ...

Silent Cerebral Infarction During iTTP Can Affect Cognition

Silent cerebral infarction (SCI) refers to the often-​incidental finding of brain infarction in the absence of overt neurologic deficits. Magnetic resonance imaging (MRI) evidence suggests that ...

COVID-19 Bivalent Boosters Associated With Few Definitive Hematologic AEs

A cross-sectional study of U.S. safety data found few hematologic adverse events (AEs) after administration of the authorized COVID-19 bivalent booster vaccines from Pfizer-BioNTech and Moderna ...

VTE Linked to Double the Risk for Depression

Acute venous thromboembolism (VTE) was associated with a more than doubled risk for depression, according to results from a Danish study ...

Consensus Guidelines Outline Treatment of ITP Related to SARS-CoV-2 Infection, Vaccination

A group of experts from Spain recently released consensus guidelines on the management of patients with immune thrombocytopenia (ITP) in the context of infection with and vaccination ...

Better Recognition Needed for Early Diagnosis of hTTP

More recognition of hereditary thrombotic thrombocytopenic purpura (hTTP) is needed for patients to receive timely care, according to findings presented at ...

Racial and Socioeconomic Disparities Persist in U.S.-Based PE Care and Outcomes

Several racial and socioeconomic inequities continue to drive disparities in care and outcomes among patients with pulmonary embolism (PE) in the U.S. ...

Dalteparin to Apixaban for Upper Extremity DVT in Patients With Cancer

Dalteparin followed by apixaban was effective for treating deep vein thrombosis (DVT) and preserving central venous catheter (CVC) function in patients with cancer ...



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